Name | Number of supported studies | Average coverage | |
---|---|---|---|
oligodendrocyte | 8 studies | 28% ± 10% | |
glutamatergic neuron | 7 studies | 39% ± 25% | |
endothelial cell | 6 studies | 26% ± 7% | |
microglial cell | 6 studies | 24% ± 5% | |
oligodendrocyte precursor cell | 6 studies | 29% ± 11% | |
astrocyte | 6 studies | 32% ± 13% | |
macrophage | 6 studies | 20% ± 3% | |
GABAergic neuron | 5 studies | 41% ± 18% | |
epithelial cell | 4 studies | 30% ± 4% | |
ciliated cell | 4 studies | 19% ± 2% | |
interneuron | 4 studies | 40% ± 20% | |
classical monocyte | 3 studies | 20% ± 5% | |
non-classical monocyte | 3 studies | 22% ± 4% | |
retina horizontal cell | 3 studies | 18% ± 2% | |
fibroblast | 3 studies | 19% ± 3% | |
dendritic cell | 3 studies | 26% ± 6% | |
basal cell | 3 studies | 26% ± 5% | |
goblet cell | 3 studies | 23% ± 8% | |
adipocyte | 3 studies | 21% ± 2% | |
neuron | 3 studies | 26% ± 10% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
prostate | 100% | 1731.86 | 245 / 245 | 100% | 9.35 | 501 / 502 |
uterus | 100% | 1671.39 | 170 / 170 | 100% | 9.39 | 458 / 459 |
brain | 100% | 1431.57 | 2635 / 2642 | 100% | 9.53 | 705 / 705 |
breast | 100% | 1827.65 | 459 / 459 | 100% | 10.85 | 1114 / 1118 |
thymus | 100% | 1659.07 | 653 / 653 | 100% | 11.14 | 602 / 605 |
lung | 99% | 1372.85 | 575 / 578 | 100% | 7.62 | 1152 / 1155 |
bladder | 100% | 1852.00 | 21 / 21 | 99% | 7.27 | 500 / 504 |
pancreas | 99% | 1006.02 | 326 / 328 | 99% | 7.00 | 177 / 178 |
esophagus | 100% | 1510.83 | 1445 / 1445 | 98% | 6.64 | 179 / 183 |
kidney | 100% | 1245.51 | 89 / 89 | 98% | 6.91 | 880 / 901 |
liver | 100% | 887.75 | 226 / 226 | 98% | 4.72 | 396 / 406 |
ovary | 100% | 1723.18 | 180 / 180 | 97% | 5.28 | 419 / 430 |
intestine | 100% | 1634.42 | 966 / 966 | 97% | 5.80 | 512 / 527 |
stomach | 100% | 1224.26 | 359 / 359 | 97% | 5.53 | 276 / 286 |
skin | 100% | 1685.73 | 1809 / 1809 | 94% | 8.04 | 446 / 472 |
adrenal gland | 100% | 1366.10 | 258 / 258 | 94% | 5.55 | 217 / 230 |
adipose | 100% | 1807.34 | 1204 / 1204 | 0% | 0 | 0 / 0 |
blood vessel | 100% | 2151.43 | 1335 / 1335 | 0% | 0 | 0 / 0 |
lymph node | 0% | 0 | 0 / 0 | 100% | 8.32 | 29 / 29 |
muscle | 100% | 2409.48 | 803 / 803 | 0% | 0 | 0 / 0 |
spleen | 100% | 1664.24 | 241 / 241 | 0% | 0 | 0 / 0 |
tonsil | 0% | 0 | 0 / 0 | 100% | 10.04 | 45 / 45 |
ureter | 0% | 0 | 0 / 0 | 100% | 2.91 | 1 / 1 |
peripheral blood | 98% | 1760.36 | 913 / 929 | 0% | 0 | 0 / 0 |
heart | 97% | 1602.70 | 833 / 861 | 0% | 0 | 0 / 0 |
eye | 0% | 0 | 0 / 0 | 71% | 3.43 | 57 / 80 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
GO_0045824 | Biological process | negative regulation of innate immune response |
GO_0098535 | Biological process | de novo centriole assembly involved in multi-ciliated epithelial cell differentiation |
GO_0051301 | Biological process | cell division |
GO_0050821 | Biological process | protein stabilization |
GO_0051225 | Biological process | spindle assembly |
GO_0042770 | Biological process | signal transduction in response to DNA damage |
GO_0007099 | Biological process | centriole replication |
GO_1900045 | Biological process | negative regulation of protein K63-linked ubiquitination |
GO_0000077 | Biological process | DNA damage checkpoint signaling |
GO_0005814 | Cellular component | centriole |
GO_0005813 | Cellular component | centrosome |
GO_0005829 | Cellular component | cytosol |
GO_0000922 | Cellular component | spindle pole |
GO_0034451 | Cellular component | centriolar satellite |
GO_0060090 | Molecular function | molecular adaptor activity |
GO_0005515 | Molecular function | protein binding |
Gene name | CEP63 |
Protein name | Centrosomal protein of 63 kDa Centrosomal protein of 63 kDa (Cep63) |
Synonyms | |
Description | FUNCTION: Required for normal spindle assembly . Plays a key role in mother-centriole-dependent centriole duplication; the function seems also to involve CEP152, CDK5RAP2 and WDR62 through a stepwise assembled complex at the centrosome that recruits CDK2 required for centriole duplication . Reported to be required for centrosomal recruitment of CEP152; however, this function has been questioned . Also recruits CDK1 to centrosomes . Plays a role in DNA damage response . Following DNA damage, such as double-strand breaks (DSBs), is removed from centrosomes; this leads to the inactivation of spindle assembly and delay in mitotic progression . Promotes stabilization of FXR1 protein by inhibiting FXR1 ubiquitination . . |
Accessions | H0YAE6 ENST00000684574.1 A0A804HKH7 A0A804HL17 ENST00000684256.1 ENST00000682689.1 ENST00000683608.1 [Q96MT8-2] ENST00000683931.1 ENST00000683190.1 A0A804HHU4 ENST00000683177.1 [Q96MT8-3] ENST00000682402.1 ENST00000683949.1 A0A804HKF0 ENST00000682458.1 ENST00000684170.1 ENST00000682858.1 [Q96MT8-3] ENST00000683940.1 ENST00000682670.1 ENST00000683861.1 [Q96MT8-3] ENST00000683118.1 A0A804HKM0 ENST00000511574.6 A0A804HJI5 A0A804HJT2 A0A3B3IT05 ENST00000684492.1 ENST00000354446.7 [Q96MT8-4] A0A804HJ73 A0A804HK67 ENST00000682316.1 ENST00000682937.1 ENST00000682593.1 ENST00000683556.1 ENST00000513612.7 [Q96MT8-1] ENST00000513295.2 ENST00000682007.1 ENST00000684777.1 ENST00000682042.1 [Q96MT8-3] ENST00000683732.1 ENST00000684588.1 ENST00000606977.5 [Q96MT8-1] ENST00000682685.1 ENST00000684481.1 ENST00000508778.2 ENST00000682190.1 ENST00000684217.1 [Q96MT8-2] A0A804HI78 H0Y900 A0A804HIX3 ENST00000675561.1 [Q96MT8-1] ENST00000514678.2 ENST00000383229.8 [Q96MT8-2] ENST00000682822.1 A0A804HJ63 ENST00000684677.1 [Q96MT8-2] ENST00000332047.10 [Q96MT8-3] A0A804HJF9 A0A804HKK0 ENST00000682013.1 ENST00000682800.1 [Q96MT8-3] ENST00000504929.6 ENST00000620544.5 [Q96MT8-4] ENST00000684060.1 Q96MT8 A0A804HI22 ENST00000512894 ENST00000683245.1 A0A804HKQ7 ENST00000683997.1 ENST00000512894.6 [Q96MT8-4] ENST00000682954.1 ENST00000682717.1 A0A804HJF1 D6R9Q4 ENST00000683596.1 [Q96MT8-1] D6RAY6 ENST00000650279.2 A0A804HJP1 A0A804HKR1 H0YAL1 |