DEUP1 | OmnibusX

Name	Number of supported studies	Average coverage
deuterosomal cell	4 studies	33% ± 1%	Explore

sc-RNAseq data

Insufficient scRNA-seq data for expression of DEUP1 at tissue level.

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
prostate	86%	57.42	210 / 245	39%	1.01	194 / 502
adrenal gland	92%	34.22	238 / 258	31%	0.79	72 / 230
thymus	98%	38.57	642 / 653	7%	0.15	45 / 605
ovary	67%	12.17	121 / 180	38%	1.09	164 / 430
pancreas	86%	14.93	282 / 328	9%	0.16	16 / 178
kidney	73%	11.28	65 / 89	5%	0.10	44 / 901
lung	53%	22.78	309 / 578	23%	0.54	261 / 1155
breast	45%	12.09	207 / 459	12%	0.31	132 / 1118
uterus	43%	10.51	73 / 170	12%	0.29	56 / 459
stomach	40%	3.89	142 / 359	3%	0.05	8 / 286
brain	42%	15.64	1098 / 2642	0%	0.01	2 / 705
bladder	19%	1.24	4 / 21	5%	0.24	27 / 504
esophagus	13%	1.40	191 / 1445	9%	0.19	16 / 183
intestine	16%	1.44	156 / 966	3%	0.07	18 / 527
skin	17%	1.66	306 / 1809	0%	0.01	2 / 472
spleen	13%	1.05	32 / 241	0%	0	0 / 0
liver	11%	1.02	24 / 226	2%	0.04	8 / 406
tonsil	0%	0	0 / 0	11%	0.18	5 / 45
blood vessel	11%	0.95	147 / 1335	0%	0	0 / 0
heart	8%	0.60	69 / 861	0%	0	0 / 0
peripheral blood	8%	0.96	71 / 929	0%	0	0 / 0
adipose	5%	0.62	65 / 1204	0%	0	0 / 0
muscle	2%	0.56	19 / 803	0%	0	0 / 0
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
eye	0%	0	0 / 0	0%	0	0 / 80
gingiva	0%	0	0 / 0	0%	0	0 / 0
lymph node	0%	0	0 / 0	0%	0	0 / 29
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0
ureter	0%	0	0 / 0	0%	0	0 / 1

GO_0098535	Biological process	de novo centriole assembly involved in multi-ciliated epithelial cell differentiation
GO_1903251	Biological process	multi-ciliated epithelial cell differentiation
GO_0030030	Biological process	cell projection organization
GO_0007099	Biological process	centriole replication
GO_0005814	Cellular component	centriole
GO_0098536	Cellular component	deuterosome
GO_0005737	Cellular component	cytoplasm
GO_0042802	Molecular function	identical protein binding
GO_0005515	Molecular function	protein binding

Gene name	DEUP1
Protein name	Deuterosome assembly protein 1 Deuterosome assembly protein 1 (Coiled-coil domain-containing protein 67)
Synonyms	CCDC67
Description	FUNCTION: Key structural component of the deuterosome, a structure that promotes de novo centriole amplification in multiciliated cells. Deuterosome-mediated centriole amplification occurs in terminally differentiated multiciliated cells and can generate more than 100 centrioles. Probably sufficient for the specification and formation of the deuterosome inner core. Interacts with CEP152 and recruits PLK4 to activate centriole biogenesis (By similarity). .
Accessions	ENST00000532819.5 E9PLX9 ENST00000298050.9 [Q05D60-1] A0A5H1ZRS0 A0A0A0MTD8 Q05D60 ENST00000530273.5 E9PIY2 ENST00000525646.1 A0A087WVI3 ENST00000530862.6 ENST00000531792.5 A0A088AWP1 ENST00000527307.2 ENST00000618031.4 E9PPB2 ENST00000531448.5 E9PMP4 ENST00000534747.5 E9PLL9

DEUP1 report