TRAIL-activated apoptotic signaling pathway

I. Involved cell types

Genes
Cell types
No. of supported studies
Group 1
TNFRSF10ATNFRSF10B
epithelial cell
6 studies
Group 2
SPI1ZDHHC3
myeloid cellclassical monocyte
10 studies
Group 3
CASP8
lymphocyteepithelial cell
31 studies

II. Literature review

[source]
NameTRAIL-activated apoptotic signaling pathway
IDGO_0036462
collection_id

Biological process

Exact synonym

TRAIL-activated extrinsic apoptotic signaling pathway, TRAIL-induced apoptotic signaling pathway, tumor necrosis factor-related apoptosis-inducing ligand apoptotic signaling pathway

Description

An extrinsic apoptotic signaling pathway initiated by the binding of the ligand TRAIL (tumor necrosis factor-related apoptosis-inducing ligand) to a death receptor on the cell surface.

External URL
Genes
TNFRSF10ASPI1TNFRSF10CTNFRSF10BFADDCASP8ZDHHC3