I. Expression across cell types
Name | Number of supported studies  | Average coverage | |
|---|---|---|---|
| neutrophil | 3 studies | 23% ± 2% |
Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| neutrophil | 3 studies | 23% ± 2% |
Insufficient scRNA-seq data for expression of TNFRSF10C at tissue level.
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| thymus | 99% | 154.04 | 645 / 653 | 90% | 11.67 | 545 / 605 |
| kidney | 100% | 161.18 | 89 / 89 | 85% | 5.22 | 769 / 901 |
| lung | 100% | 510.65 | 578 / 578 | 70% | 3.94 | 814 / 1155 |
| breast | 99% | 99.23 | 453 / 459 | 54% | 2.10 | 608 / 1118 |
| adrenal gland | 99% | 138.90 | 256 / 258 | 49% | 1.84 | 113 / 230 |
| pancreas | 70% | 49.44 | 230 / 328 | 71% | 2.18 | 127 / 178 |
| stomach | 67% | 57.88 | 242 / 359 | 65% | 2.85 | 185 / 286 |
| bladder | 86% | 77.38 | 18 / 21 | 41% | 1.80 | 207 / 504 |
| prostate | 93% | 93.65 | 227 / 245 | 29% | 0.65 | 148 / 502 |
| uterus | 86% | 72.54 | 147 / 170 | 34% | 1.02 | 154 / 459 |
| intestine | 63% | 51.48 | 612 / 966 | 53% | 2.07 | 278 / 527 |
| spleen | 100% | 1297.08 | 241 / 241 | 0% | 0 | 0 / 0 |
| brain | 49% | 34.37 | 1294 / 2642 | 51% | 1.52 | 358 / 705 |
| adipose | 99% | 166.55 | 1189 / 1204 | 0% | 0 | 0 / 0 |
| liver | 77% | 58.91 | 174 / 226 | 21% | 1.03 | 85 / 406 |
| peripheral blood | 97% | 14777.75 | 897 / 929 | 0% | 0 | 0 / 0 |
| esophagus | 50% | 32.07 | 718 / 1445 | 39% | 1.12 | 72 / 183 |
| heart | 87% | 73.78 | 751 / 861 | 0% | 0 | 0 / 0 |
| blood vessel | 81% | 90.41 | 1086 / 1335 | 0% | 0 | 0 / 0 |
| ovary | 50% | 26.09 | 90 / 180 | 25% | 0.57 | 108 / 430 |
| skin | 42% | 60.49 | 762 / 1809 | 26% | 0.66 | 125 / 472 |
| lymph node | 0% | 0 | 0 / 0 | 48% | 0.89 | 14 / 29 |
| tonsil | 0% | 0 | 0 / 0 | 40% | 0.86 | 18 / 45 |
| eye | 0% | 0 | 0 / 0 | 20% | 0.55 | 16 / 80 |
| muscle | 17% | 8.77 | 140 / 803 | 0% | 0 | 0 / 0 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
| GO_0036462 | Biological process | TRAIL-activated apoptotic signaling pathway |
| GO_0043065 | Biological process | positive regulation of apoptotic process |
| GO_0009986 | Cellular component | cell surface |
| GO_0098552 | Cellular component | side of membrane |
| GO_0005886 | Cellular component | plasma membrane |
| GO_0004888 | Molecular function | transmembrane signaling receptor activity |
| GO_0045569 | Molecular function | TRAIL binding |
| GO_0005515 | Molecular function | protein binding |
| Gene name | TNFRSF10C |
| Protein name | TNFRSF10C protein TNF receptor superfamily member 10c Tumor necrosis factor receptor superfamily member 10C (Antagonist decoy receptor for TRAIL/Apo-2L) (Decoy TRAIL receptor without death domain) (Decoy receptor 1) (DcR1) (Lymphocyte inhibitor of TRAIL) (TNF-related apoptosis-inducing ligand receptor 3) (TRAIL receptor 3) (TRAIL-R3) (TRAIL receptor without an intracellular domain) (CD antigen CD263) |
| Synonyms | UNQ321/PRO366 TRAILR3 LIT DCR1 TRID |
| Description | FUNCTION: Receptor for the cytotoxic ligand TRAIL. Lacks a cytoplasmic death domain and hence is not capable of inducing apoptosis. May protect cells against TRAIL mediated apoptosis by competing with TRAIL-R1 and R2 for binding to the ligand. |
| Accessions | Q05D71 E5RJI1 ENST00000517558.1 ENST00000356864.4 O14798 |
