immunoglobulin V(D)J recombination

I. Involved cell types

Genes
Cell types
No. of supported studies
Group 1
TCF3PRKDC
B cellprecursor B cellplasma cellplasmablast
16 studies
Group 2
LIG4XRCC4
dopaminergic neuronglutamatergic neuron
6 studies
Group 3
CYREN
epithelial cellhematopoietic stem cellneuronglial cell
10 studies

II. Literature review

[source]
Nameimmunoglobulin V(D)J recombination
IDGO_0033152
collection_id

Biological process

Exact synonym

immunoglobulin V(D)J joining

Description

The process in which immunoglobulin gene segments are recombined within a single locus utilizing the conserved heptamer and nonomer recombination signal sequences (RSS). For immunoglobulin heavy chains V, D, and J gene segments are joined, and for immunoglobulin light chains V and J gene segments are joined.

External URL
Genes
LIG4PRKDCXRCC4NHEJ1TCF3CYREN