ZNF609 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_2000291Biological processregulation of myoblast proliferation
GO_2001224Biological processpositive regulation of neuron migration
GO_0007517Biological processmuscle organ development
GO_0045944Biological processpositive regulation of transcription by RNA polymerase II
GO_0006357Biological processregulation of transcription by RNA polymerase II
GO_0005654Cellular componentnucleoplasm
GO_0005634Cellular componentnucleus
GO_1990841Molecular functionpromoter-specific chromatin binding
GO_0046872Molecular functionmetal ion binding

IV. Literature review

[source]
Gene nameZNF609
Protein nameZinc finger protein 609
ZNF609 protein
Alternative protein ZNF609
SynonymsKIAA0295
DescriptionFUNCTION: Transcription factor, which activates RAG1, and possibly RAG2, transcription. Through the regulation of RAG1/2 expression, may regulate thymocyte maturation. Along with NIPBL and the multiprotein complex Integrator, promotes cortical neuron migration during brain development by regulating the transcription of crucial genes in this process. Preferentially binds promoters containing paused RNA polymerase II. Up-regulates the expression of SEMA3A, NRP1, PLXND1 and GABBR2 genes, among others. .; FUNCTION: [Isoform 2]: Involved in the regulation of myoblast proliferation during myogenesis. .

AccessionsENST00000326648.5 [O15014-1]
E7ERY8
A5PKW6
L8ECF6
O15014
ENST00000416172.1