ZNF593 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_0042254Biological processribosome biogenesis
GO_1903026Biological processnegative regulation of RNA polymerase II regulatory region sequence-specific DNA binding
GO_0045944Biological processpositive regulation of transcription by RNA polymerase II
GO_0005730Cellular componentnucleolus
GO_0005654Cellular componentnucleoplasm
GO_0005737Cellular componentcytoplasm
GO_0003677Molecular functionDNA binding
GO_1990275Molecular functionpreribosome binding
GO_0005515Molecular functionprotein binding
GO_0008270Molecular functionzinc ion binding

IV. Literature review

[source]
Gene nameZNF593
Protein nameZinc finger protein 593 (Zinc finger protein T86)
Zinc finger protein 593
SynonymsZT86
DescriptionFUNCTION: Involved in pre-60S ribosomal particles maturation by promoting the nuclear export of the 60S ribosome . Negatively modulates the DNA binding activity of Oct-2 and therefore its transcriptional regulatory activity . .

AccessionsENST00000270812.6
ENST00000374266.7
A9J4F5
O00488