ZNF462 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_0006325Biological processchromatin organization
GO_0045944Biological processpositive regulation of transcription by RNA polymerase II
GO_0005654Cellular componentnucleoplasm
GO_0005634Cellular componentnucleus
GO_0003677Molecular functionDNA binding
GO_0005515Molecular functionprotein binding
GO_0046872Molecular functionmetal ion binding

IV. Literature review

[source]
Gene nameZNF462
Protein nameZinc finger protein 462
Zinc finger protein 462 (Zinc finger PBX1-interacting protein) (ZFPIP)
SynonymsKIAA1803
DescriptionFUNCTION: Zinc finger nuclear factor involved in transcription by regulating chromatin structure and organization . Involved in the pluripotency and differentiation of embryonic stem cells by regulating SOX2, POU5F1/OCT4, and NANOG . By binding PBX1, prevents the heterodimerization of PBX1 and HOXA9 and their binding to DNA (By similarity). Regulates neuronal development and neural cell differentiation . .

AccessionsQ96JM2
H3BLX4
ENST00000472574.1
ENST00000441147.6 [Q96JM2-2]
H0Y6H9
U3KQU3
ENST00000427098.1
ENST00000277225.10 [Q96JM2-1]
ENST00000374686.6