Name | Number of supported studies | Average coverage | |
---|---|---|---|
macrophage | 40 studies | 42% ± 13% | |
conventional dendritic cell | 28 studies | 37% ± 16% | |
classical monocyte | 24 studies | 40% ± 14% | |
monocyte | 21 studies | 33% ± 12% | |
non-classical monocyte | 20 studies | 33% ± 10% | |
plasmacytoid dendritic cell | 14 studies | 34% ± 9% | |
dendritic cell | 14 studies | 39% ± 22% | |
myeloid cell | 13 studies | 42% ± 18% | |
regulatory T cell | 12 studies | 20% ± 3% | |
B cell | 10 studies | 20% ± 2% | |
endothelial cell | 9 studies | 20% ± 4% | |
alveolar macrophage | 8 studies | 35% ± 14% | |
CD16-positive, CD56-dim natural killer cell, human | 8 studies | 21% ± 5% | |
natural killer cell | 8 studies | 18% ± 3% | |
memory B cell | 7 studies | 20% ± 6% | |
platelet | 6 studies | 22% ± 7% | |
mononuclear phagocyte | 6 studies | 36% ± 16% | |
leukocyte | 6 studies | 23% ± 7% | |
astrocyte | 5 studies | 23% ± 5% | |
gamma-delta T cell | 5 studies | 17% ± 1% | |
naive B cell | 4 studies | 23% ± 5% | |
CD8-positive, alpha-beta T cell | 4 studies | 18% ± 3% | |
epithelial cell | 4 studies | 31% ± 13% | |
fibroblast | 4 studies | 21% ± 7% | |
neutrophil | 4 studies | 21% ± 5% | |
hematopoietic precursor cell | 3 studies | 37% ± 4% | |
common myeloid progenitor | 3 studies | 25% ± 12% | |
microglial cell | 3 studies | 33% ± 8% | |
tissue-resident macrophage | 3 studies | 44% ± 15% | |
abnormal cell | 3 studies | 31% ± 9% | |
intermediate monocyte | 3 studies | 47% ± 20% | |
inflammatory macrophage | 3 studies | 32% ± 11% | |
GABAergic neuron | 3 studies | 27% ± 7% | |
glutamatergic neuron | 3 studies | 34% ± 10% | |
enterocyte | 3 studies | 20% ± 3% | |
hematopoietic stem cell | 3 studies | 30% ± 5% | |
CD8-positive, alpha-beta memory T cell | 3 studies | 22% ± 5% | |
double negative thymocyte | 3 studies | 17% ± 1% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
esophagus | 100% | 7683.65 | 1445 / 1445 | 100% | 99.00 | 183 / 183 |
brain | 100% | 9055.90 | 2638 / 2642 | 100% | 123.93 | 705 / 705 |
thymus | 100% | 8479.98 | 653 / 653 | 100% | 79.53 | 604 / 605 |
liver | 100% | 6366.82 | 226 / 226 | 100% | 86.20 | 405 / 406 |
skin | 100% | 8828.20 | 1808 / 1809 | 100% | 254.04 | 471 / 472 |
stomach | 100% | 6705.47 | 359 / 359 | 100% | 89.79 | 285 / 286 |
intestine | 100% | 10513.03 | 966 / 966 | 100% | 73.08 | 525 / 527 |
adrenal gland | 100% | 24020.82 | 258 / 258 | 100% | 129.47 | 229 / 230 |
kidney | 100% | 9519.52 | 89 / 89 | 99% | 139.30 | 896 / 901 |
ovary | 100% | 8111.42 | 180 / 180 | 99% | 58.52 | 426 / 430 |
prostate | 100% | 7051.88 | 244 / 245 | 99% | 67.25 | 499 / 502 |
lung | 100% | 14270.92 | 578 / 578 | 99% | 86.63 | 1143 / 1155 |
breast | 100% | 7893.42 | 459 / 459 | 99% | 80.51 | 1106 / 1118 |
uterus | 100% | 10813.56 | 170 / 170 | 98% | 54.82 | 450 / 459 |
bladder | 100% | 8797.90 | 21 / 21 | 95% | 57.75 | 480 / 504 |
pancreas | 97% | 3452.77 | 319 / 328 | 98% | 71.38 | 174 / 178 |
adipose | 100% | 10713.38 | 1204 / 1204 | 0% | 0 | 0 / 0 |
eye | 0% | 0 | 0 / 0 | 100% | 264.44 | 80 / 80 |
lymph node | 0% | 0 | 0 / 0 | 100% | 110.40 | 29 / 29 |
spleen | 100% | 22824.70 | 241 / 241 | 0% | 0 | 0 / 0 |
ureter | 0% | 0 | 0 / 0 | 100% | 31.26 | 1 / 1 |
blood vessel | 100% | 8780.60 | 1333 / 1335 | 0% | 0 | 0 / 0 |
peripheral blood | 100% | 12019.52 | 927 / 929 | 0% | 0 | 0 / 0 |
heart | 98% | 6233.59 | 844 / 861 | 0% | 0 | 0 / 0 |
tonsil | 0% | 0 | 0 / 0 | 98% | 54.17 | 44 / 45 |
muscle | 94% | 2995.14 | 755 / 803 | 0% | 0 | 0 / 0 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
GO_0007040 | Biological process | lysosome organization |
GO_0030855 | Biological process | epithelial cell differentiation |
GO_0050885 | Biological process | neuromuscular process controlling balance |
GO_0070198 | Biological process | protein localization to chromosome, telomeric region |
GO_0006508 | Biological process | proteolysis |
GO_0030163 | Biological process | protein catabolic process |
GO_0045453 | Biological process | bone resorption |
GO_0007417 | Biological process | central nervous system development |
GO_1905146 | Biological process | lysosomal protein catabolic process |
GO_0007399 | Biological process | nervous system development |
GO_0006629 | Biological process | lipid metabolic process |
GO_0043171 | Biological process | peptide catabolic process |
GO_0045121 | Cellular component | membrane raft |
GO_0055037 | Cellular component | recycling endosome |
GO_0005764 | Cellular component | lysosome |
GO_0070062 | Cellular component | extracellular exosome |
GO_0005794 | Cellular component | Golgi apparatus |
GO_0043202 | Cellular component | lysosomal lumen |
GO_0042470 | Cellular component | melanosome |
GO_0008233 | Molecular function | peptidase activity |
GO_0004175 | Molecular function | endopeptidase activity |
GO_0004252 | Molecular function | serine-type endopeptidase activity |
GO_0008240 | Molecular function | tripeptidyl-peptidase activity |
GO_0042277 | Molecular function | peptide binding |
GO_0008236 | Molecular function | serine-type peptidase activity |
GO_0120146 | Molecular function | sulfatide binding |
GO_0046872 | Molecular function | metal ion binding |
GO_0035727 | Molecular function | lysophosphatidic acid binding |
GO_0005515 | Molecular function | protein binding |
Gene name | TPP1 |
Protein name | Tripeptidyl-peptidase 1 (EC 3.4.14.9) (Tripeptidyl aminopeptidase) (Tripeptidyl-peptidase I) Tripeptidyl peptidase 1 Tripeptidyl-peptidase 1 (TPP-1) (EC 3.4.14.9) (Cell growth-inhibiting gene 1 protein) (Lysosomal pepstatin-insensitive protease) (LPIC) (Tripeptidyl aminopeptidase) (Tripeptidyl-peptidase I) (TPP-I) |
Synonyms | UNQ267/PRO304 GIG1 CLN2 |
Description | FUNCTION: Lysosomal serine protease with tripeptidyl-peptidase I activity . May act as a non-specific lysosomal peptidase which generates tripeptides from the breakdown products produced by lysosomal proteinases . Requires substrates with an unsubstituted N-terminus . . |
Accessions | A0A2R8YE64 A0A804HJ17 ENST00000436873.7 ENST00000642892.1 [O14773-2] A0A2R8Y7I4 E9PME9 ENST00000299427.12 [O14773-1] ENST00000644810.1 ENST00000533371.6 [O14773-2] ENST00000682424.1 ENST00000644218.1 ENST00000645620.1 [O14773-2] ENST00000643342.1 ENST00000645285.1 A0A2R8YD45 ENST00000643516.1 A0A2R8Y6T9 A0A2R8YD72 A0A2R8Y7U1 E7EV34 A0A2R8YGD1 ENST00000528657.2 E9PPA4 ENST00000643439.1 A0A2R8YCK4 ENST00000647209.1 O14773 ENST00000644683.1 ENST00000644933.1 ENST00000531754.2 ENST00000647152.1 [O14773-2] A0A2R8YDY1 ENST00000528571.6 |