TMCC1 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_0007029Biological processendoplasmic reticulum organization
GO_0097750Biological processendosome membrane tubulation
GO_0016197Biological processendosomal transport
GO_0140285Biological processendosome fission
GO_0090148Biological processmembrane fission
GO_0140284Cellular componentendoplasmic reticulum-endosome membrane contact site
GO_0005791Cellular componentrough endoplasmic reticulum
GO_0005829Cellular componentcytosol
GO_0012505Cellular componentendomembrane system
GO_0005789Cellular componentendoplasmic reticulum membrane
GO_0042802Molecular functionidentical protein binding
GO_0005515Molecular functionprotein binding

IV. Literature review

[source]
Gene nameTMCC1
Protein nameTransmembrane and coiled-coil domains protein 1
Transmembrane and coiled-coil domain family 1
TMCC1 protein
Transmembrane and coiled-coil domain family 1 (cDNA FLJ42680 fis, clone BRAMY2040592, highly similar to Transmembrane and coiled-coil domains protein 1)
SynonymsDKFZp686H13261
KIAA0779
DescriptionFUNCTION: Endoplasmic reticulum membrane protein that promotes endoplasmic reticulum-associated endosome fission . Localizes to contact sites between the endoplasmic reticulum and endosomes and acts by promoting recruitment of the endoplasmic reticulum to endosome tubules for fission . Endosome membrane fission of early and late endosomes is essential to separate regions destined for lysosomal degradation from carriers to be recycled to the plasma membrane . .

AccessionsENST00000432054.6
A0A8V8TLJ9
ENST00000505616.5
D6RH19
ENST00000510323.1
ENST00000648771.1
ENST00000393238.8 [O94876-1]
D6RBT7
ENST00000426664.6
ENST00000698215.1 [O94876-2]
ENST00000698214.1
Q8N4H2
Q6N039
E9PC87
O94876