TIMM10 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_0007605Biological processsensory perception of sound
GO_0006626Biological processprotein targeting to mitochondrion
GO_0045039Biological processprotein insertion into mitochondrial inner membrane
GO_0042721Cellular componentTIM22 mitochondrial import inner membrane insertion complex
GO_0005758Cellular componentmitochondrial intermembrane space
GO_0042719Cellular componentmitochondrial intermembrane space protein transporter complex
GO_0005739Cellular componentmitochondrion
GO_0005743Cellular componentmitochondrial inner membrane
GO_0005744Cellular componentTIM23 mitochondrial import inner membrane translocase complex
GO_0042803Molecular functionprotein homodimerization activity
GO_0051087Molecular functionprotein-folding chaperone binding
GO_0032977Molecular functionmembrane insertase activity
GO_0005515Molecular functionprotein binding
GO_0008270Molecular functionzinc ion binding

IV. Literature review

[source]
Gene nameTIMM10
Protein nameMitochondrial import inner membrane translocase subunit Tim10
SynonymsTIM10
DescriptionFUNCTION: Mitochondrial intermembrane chaperone that participates in the import and insertion of multi-pass transmembrane proteins into the mitochondrial inner membrane. May also be required for the transfer of beta-barrel precursors from the TOM complex to the sorting and assembly machinery (SAM complex) of the outer membrane. Acts as a chaperone-like protein that protects the hydrophobic precursors from aggregation and guide them through the mitochondrial intermembrane space. .

AccessionsENST00000257245.9
ENST00000525158.1
P62072
ENST00000525587.1