TIM22 mitochondrial import inner membrane insertion complex

I. Literature review

[source]
NameTIM22 mitochondrial import inner membrane insertion complex
IDGO_0042721
collection_id

Cellular component

Exact synonym

Tim22 complex, mitochondrial inner membrane protein insertion complex

Description

A multi-subunit complex embedded in the mitochondrial inner membrane that mediates the inner membrane insertion of multi-transmembrane spanning proteins that contain internal targeting elements. In yeast cells, TIM22 is a 300-kDa complex, consisting of four membrane integral subunits, Tim22, Tim54, Tim18 and Sdh3, and a peripheral chaperone complex consisting of the small TIM proteins, Tim9-Tim10-Tim12.

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Genes