TIMM10B report

I. Expression across cell types

II. Expression across tissues

sc-RNAseq data

Insufficient scRNA-seq data for expression of TIMM10B at tissue level.

III. Associated gene sets

GO_0007160Biological processcell-matrix adhesion
GO_0045039Biological processprotein insertion into mitochondrial inner membrane
GO_0042721Cellular componentTIM22 mitochondrial import inner membrane insertion complex
GO_0005758Cellular componentmitochondrial intermembrane space
GO_0042719Cellular componentmitochondrial intermembrane space protein transporter complex
GO_0005743Cellular componentmitochondrial inner membrane
GO_0051082Molecular functionunfolded protein binding
GO_0005515Molecular functionprotein binding
GO_0046872Molecular functionmetal ion binding

IV. Literature review

[source]
Gene nameTIMM10B
Protein nameMitochondrial import inner membrane translocase subunit Tim10 B (Fracture callus protein 1) (FxC1) (Mitochondrial import inner membrane translocase subunit Tim9 B) (TIMM10B) (Tim10b)
Translocase of inner mitochondrial membrane 10B
SynonymsFXC1
TIM9B
TIMM9B
DescriptionFUNCTION: Component of the TIM22 complex, a complex that mediates the import and insertion of multi-pass transmembrane proteins into the mitochondrial inner membrane. The TIM22 complex forms a twin-pore translocase that uses the membrane potential as the external driving force. In the TIM22 complex, it may act as a docking point for the soluble 70 kDa complex that guides the target proteins in transit through the aqueous mitochondrial intermembrane space. .

AccessionsENST00000533379.1
F2Z2B0
ENST00000254616.11
Q9Y5J6
ENST00000531462.5
ENST00000530751.1
ENST00000639224.1