Name | Number of supported studies | Average coverage | |
---|---|---|---|
endothelial cell | 18 studies | 38% ± 14% | |
fibroblast | 12 studies | 27% ± 8% | |
astrocyte | 9 studies | 43% ± 17% | |
adipocyte | 7 studies | 23% ± 4% | |
pericyte | 7 studies | 30% ± 13% | |
smooth muscle cell | 7 studies | 28% ± 7% | |
endothelial cell of lymphatic vessel | 7 studies | 35% ± 12% | |
type II pneumocyte | 6 studies | 39% ± 10% | |
epithelial cell | 5 studies | 35% ± 9% | |
basal cell | 5 studies | 42% ± 24% | |
connective tissue cell | 4 studies | 23% ± 6% | |
club cell | 4 studies | 27% ± 10% | |
podocyte | 3 studies | 50% ± 21% | |
vein endothelial cell | 3 studies | 28% ± 16% | |
endothelial cell of vascular tree | 3 studies | 37% ± 16% | |
retinal pigment epithelial cell | 3 studies | 32% ± 18% | |
myofibroblast cell | 3 studies | 29% ± 9% | |
respiratory goblet cell | 3 studies | 31% ± 18% | |
mesothelial cell | 3 studies | 26% ± 6% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
breast | 100% | 5012.52 | 459 / 459 | 88% | 27.67 | 982 / 1118 |
uterus | 100% | 4276.09 | 170 / 170 | 86% | 32.66 | 394 / 459 |
lung | 100% | 2623.07 | 576 / 578 | 86% | 23.75 | 992 / 1155 |
prostate | 100% | 3032.09 | 244 / 245 | 84% | 10.35 | 423 / 502 |
ovary | 100% | 3750.79 | 180 / 180 | 80% | 24.15 | 343 / 430 |
thymus | 100% | 4777.29 | 653 / 653 | 79% | 20.79 | 476 / 605 |
esophagus | 98% | 3144.64 | 1412 / 1445 | 80% | 18.68 | 147 / 183 |
kidney | 100% | 1987.88 | 89 / 89 | 67% | 10.31 | 602 / 901 |
skin | 78% | 1350.98 | 1407 / 1809 | 88% | 19.16 | 416 / 472 |
liver | 88% | 896.78 | 198 / 226 | 77% | 12.98 | 311 / 406 |
brain | 55% | 423.35 | 1448 / 2642 | 98% | 32.25 | 694 / 705 |
bladder | 100% | 2627.05 | 21 / 21 | 49% | 10.03 | 247 / 504 |
intestine | 95% | 2805.04 | 922 / 966 | 36% | 3.53 | 190 / 527 |
adrenal gland | 69% | 597.97 | 178 / 258 | 50% | 4.94 | 116 / 230 |
stomach | 64% | 1192.84 | 231 / 359 | 46% | 5.82 | 132 / 286 |
adipose | 100% | 4866.92 | 1204 / 1204 | 0% | 0 | 0 / 0 |
blood vessel | 100% | 4839.26 | 1335 / 1335 | 0% | 0 | 0 / 0 |
eye | 0% | 0 | 0 / 0 | 100% | 24.59 | 80 / 80 |
spleen | 100% | 1699.55 | 241 / 241 | 0% | 0 | 0 / 0 |
heart | 99% | 1647.76 | 851 / 861 | 0% | 0 | 0 / 0 |
muscle | 95% | 1221.67 | 760 / 803 | 0% | 0 | 0 / 0 |
pancreas | 14% | 102.79 | 46 / 328 | 80% | 8.91 | 142 / 178 |
tonsil | 0% | 0 | 0 / 0 | 93% | 23.07 | 42 / 45 |
lymph node | 0% | 0 | 0 / 0 | 41% | 2.94 | 12 / 29 |
peripheral blood | 0% | 2.39 | 3 / 929 | 0% | 0 | 0 / 0 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
GO_0006325 | Biological process | chromatin organization |
GO_0030111 | Biological process | regulation of Wnt signaling pathway |
GO_0006355 | Biological process | regulation of DNA-templated transcription |
GO_0060070 | Biological process | canonical Wnt signaling pathway |
GO_0006357 | Biological process | regulation of transcription by RNA polymerase II |
GO_1990907 | Cellular component | beta-catenin-TCF complex |
GO_0005654 | Cellular component | nucleoplasm |
GO_0005829 | Cellular component | cytosol |
GO_0000785 | Cellular component | chromatin |
GO_0005634 | Cellular component | nucleus |
GO_0003677 | Molecular function | DNA binding |
GO_1990837 | Molecular function | sequence-specific double-stranded DNA binding |
GO_0000978 | Molecular function | RNA polymerase II cis-regulatory region sequence-specific DNA binding |
GO_0003700 | Molecular function | DNA-binding transcription factor activity |
GO_0005515 | Molecular function | protein binding |
GO_0000981 | Molecular function | DNA-binding transcription factor activity, RNA polymerase II-specific |
Gene name | TCF7L1 |
Protein name | Transcription factor 7 like 1 Uncharacterized protein TCF7L1 Transcription factor 7-like 1 (HMG box transcription factor 3) (TCF-3) |
Synonyms | TCF3 |
Description | FUNCTION: Participates in the Wnt signaling pathway. Binds to DNA and acts as a repressor in the absence of CTNNB1, and as an activator in its presence. Necessary for the terminal differentiation of epidermal cells, the formation of keratohyalin granules and the development of the barrier function of the epidermis (By similarity). Down-regulates NQO1, leading to increased mitomycin c resistance. . |
Accessions | C9JPE3 Q9HCS4 ENST00000709854.1 Q53T87 ENST00000282111.4 ENST00000442813.1 |