STX16 report

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I. Expression across cell types

Cell ontologyData table

Name	Number of supported studies	Average coverage
endothelial cell	9 studies	25% ± 8%	Explore
regulatory T cell	9 studies	19% ± 3%	Explore
naive thymus-derived CD4-positive, alpha-beta T cell	7 studies	21% ± 8%	Explore
classical monocyte	7 studies	25% ± 12%	Explore
astrocyte	7 studies	36% ± 16%	Explore
CD16-negative, CD56-bright natural killer cell, human	6 studies	19% ± 3%	Explore
CD4-positive, alpha-beta T cell	6 studies	21% ± 5%	Explore
naive thymus-derived CD8-positive, alpha-beta T cell	6 studies	22% ± 9%	Explore
oligodendrocyte	6 studies	36% ± 14%	Explore
ciliated cell	5 studies	26% ± 9%	Explore
GABAergic neuron	5 studies	29% ± 13%	Explore
oligodendrocyte precursor cell	5 studies	39% ± 15%	Explore
plasmacytoid dendritic cell	5 studies	18% ± 4%	Explore
T cell	4 studies	17% ± 3%	Explore
natural killer cell	4 studies	17% ± 2%	Explore
non-classical monocyte	4 studies	27% ± 11%	Explore
B cell	4 studies	18% ± 1%	Explore
retinal bipolar neuron	4 studies	18% ± 2%	Explore
myeloid cell	4 studies	24% ± 2%	Explore
epithelial cell	4 studies	31% ± 10%	Explore
CD8-positive, alpha-beta T cell	4 studies	18% ± 2%	Explore
interneuron	4 studies	37% ± 26%	Explore
microglial cell	4 studies	34% ± 8%	Explore
CD4-positive, alpha-beta memory T cell	3 studies	24% ± 11%	Explore
CD16-positive, CD56-dim natural killer cell, human	3 studies	22% ± 4%	Explore
hematopoietic precursor cell	3 studies	23% ± 10%	Explore
mature NK T cell	3 studies	16% ± 1%	Explore
mucosal invariant T cell	3 studies	18% ± 2%	Explore
retinal cone cell	3 studies	18% ± 2%	Explore
fibroblast	3 studies	19% ± 4%	Explore
lymphocyte	3 studies	28% ± 4%	Explore
dendritic cell	3 studies	32% ± 15%	Explore
CD8-positive, alpha-beta memory T cell	3 studies	24% ± 8%	Explore
T follicular helper cell	3 studies	21% ± 5%	Explore
gamma-delta T cell	3 studies	25% ± 8%	Explore
macrophage	3 studies	25% ± 2%	Explore
glutamatergic neuron	3 studies	39% ± 16%	Explore

II. Expression across tissues

sc-RNAseq dataData table

Name	Number of supported studies	Average coverage
brain	7 studies	33% ± 17%	Explore
peripheral blood	3 studies	28% ± 3%	Explore
lung	3 studies	16% ± 1%	Explore

Bulk RNAseq dataData table

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
bladder	100%	12610.43	21 / 21	100%	46.81	504 / 504
esophagus	100%	10735.04	1445 / 1445	100%	40.41	183 / 183
prostate	100%	12944.04	245 / 245	100%	35.39	502 / 502
lung	100%	10497.74	578 / 578	100%	45.79	1154 / 1155
uterus	100%	14365.15	170 / 170	100%	47.87	458 / 459
brain	100%	9274.24	2636 / 2642	100%	52.12	705 / 705
thymus	100%	12239.36	653 / 653	100%	47.54	603 / 605
intestine	100%	11544.24	966 / 966	100%	46.54	525 / 527
adrenal gland	100%	9667.30	258 / 258	100%	40.88	229 / 230
breast	100%	10543.61	459 / 459	100%	46.72	1113 / 1118
ovary	100%	13107.45	180 / 180	99%	34.96	427 / 430
stomach	100%	8100.28	359 / 359	99%	44.06	284 / 286
kidney	100%	8310.12	89 / 89	99%	39.65	894 / 901
pancreas	100%	6295.13	327 / 328	99%	43.43	176 / 178
skin	100%	10305.73	1808 / 1809	99%	48.24	465 / 472
liver	100%	5427.92	226 / 226	97%	24.50	393 / 406
adipose	100%	9282.76	1204 / 1204	0%	0	0 / 0
lymph node	0%	0	0 / 0	100%	44.36	29 / 29
spleen	100%	15132.85	241 / 241	0%	0	0 / 0
tonsil	0%	0	0 / 0	100%	35.93	45 / 45
ureter	0%	0	0 / 0	100%	18.39	1 / 1
blood vessel	100%	9871.07	1334 / 1335	0%	0	0 / 0
muscle	99%	4518.27	795 / 803	0%	0	0 / 0
peripheral blood	99%	10280.37	917 / 929	0%	0	0 / 0
heart	99%	5627.05	849 / 861	0%	0	0 / 0
eye	0%	0	0 / 0	94%	31.61	75 / 80
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
gingiva	0%	0	0 / 0	0%	0	0 / 0
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0