Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| endothelial cell | 21 studies | 28% ± 13% | |
| fibroblast | 13 studies | 23% ± 14% | |
| macrophage | 12 studies | 25% ± 9% | |
| pericyte | 10 studies | 23% ± 11% | |
| epithelial cell | 10 studies | 38% ± 21% | |
| ciliated cell | 10 studies | 31% ± 13% | |
| astrocyte | 9 studies | 28% ± 12% | |
| microglial cell | 8 studies | 28% ± 9% | |
| B cell | 7 studies | 23% ± 6% | |
| basal cell | 7 studies | 42% ± 18% | |
| adipocyte | 7 studies | 26% ± 6% | |
| monocyte | 7 studies | 23% ± 6% | |
| T cell | 6 studies | 19% ± 4% | |
| type I pneumocyte | 6 studies | 24% ± 6% | |
| classical monocyte | 6 studies | 27% ± 11% | |
| non-classical monocyte | 6 studies | 29% ± 15% | |
| CD4-positive, alpha-beta T cell | 6 studies | 23% ± 5% | |
| goblet cell | 6 studies | 32% ± 21% | |
| club cell | 6 studies | 26% ± 10% | |
| dendritic cell | 6 studies | 27% ± 17% | |
| myeloid cell | 6 studies | 22% ± 5% | |
| smooth muscle cell | 6 studies | 25% ± 10% | |
| respiratory goblet cell | 5 studies | 29% ± 11% | |
| naive thymus-derived CD4-positive, alpha-beta T cell | 5 studies | 21% ± 1% | |
| retinal cone cell | 5 studies | 33% ± 13% | |
| retinal pigment epithelial cell | 5 studies | 50% ± 22% | |
| regulatory T cell | 5 studies | 20% ± 4% | |
| endothelial cell of lymphatic vessel | 5 studies | 28% ± 11% | |
| squamous epithelial cell | 4 studies | 52% ± 17% | |
| naive B cell | 4 studies | 19% ± 2% | |
| effector memory CD8-positive, alpha-beta T cell | 4 studies | 20% ± 3% | |
| mucosal invariant T cell | 4 studies | 19% ± 3% | |
| lymphocyte | 4 studies | 31% ± 10% | |
| type II pneumocyte | 4 studies | 20% ± 4% | |
| oligodendrocyte precursor cell | 4 studies | 30% ± 9% | |
| leukocyte | 4 studies | 23% ± 4% | |
| neuron | 4 studies | 30% ± 14% | |
| platelet | 3 studies | 23% ± 3% | |
| mesothelial cell | 3 studies | 18% ± 3% | |
| secretory cell | 3 studies | 35% ± 11% | |
| CD8-positive, alpha-beta memory T cell | 3 studies | 22% ± 2% | |
| memory B cell | 3 studies | 21% ± 6% | |
| cholangiocyte | 3 studies | 42% ± 22% | |
| GABAergic neuron | 3 studies | 47% ± 4% | |
| glutamatergic neuron | 3 studies | 57% ± 8% | |
| CD8-positive, alpha-beta T cell | 3 studies | 20% ± 5% | |
| enterocyte | 3 studies | 22% ± 3% | |
| myofibroblast cell | 3 studies | 24% ± 4% | |
| alveolar macrophage | 3 studies | 33% ± 11% | |
| capillary endothelial cell | 3 studies | 24% ± 6% | |
| renal alpha-intercalated cell | 3 studies | 19% ± 5% | |
| mural cell | 3 studies | 36% ± 8% | |
| mucus secreting cell | 3 studies | 23% ± 4% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| stomach | 100% | 3031.67 | 359 / 359 | 100% | 31.22 | 286 / 286 |
| intestine | 100% | 4418.22 | 965 / 966 | 100% | 31.69 | 525 / 527 |
| esophagus | 100% | 5409.36 | 1444 / 1445 | 99% | 36.16 | 182 / 183 |
| ovary | 100% | 2757.76 | 180 / 180 | 99% | 21.66 | 425 / 430 |
| lung | 99% | 3622.65 | 575 / 578 | 99% | 23.47 | 1147 / 1155 |
| skin | 100% | 7613.59 | 1809 / 1809 | 98% | 24.43 | 463 / 472 |
| bladder | 100% | 5041.38 | 21 / 21 | 98% | 28.75 | 493 / 504 |
| breast | 100% | 4265.22 | 459 / 459 | 97% | 19.53 | 1085 / 1118 |
| pancreas | 97% | 1853.31 | 319 / 328 | 98% | 23.07 | 175 / 178 |
| uterus | 100% | 3630.54 | 170 / 170 | 95% | 23.91 | 437 / 459 |
| thymus | 100% | 3283.81 | 652 / 653 | 95% | 17.65 | 574 / 605 |
| prostate | 100% | 3202.76 | 245 / 245 | 94% | 13.34 | 472 / 502 |
| kidney | 100% | 3407.17 | 89 / 89 | 93% | 14.90 | 837 / 901 |
| brain | 84% | 1356.05 | 2216 / 2642 | 94% | 8.65 | 664 / 705 |
| adrenal gland | 99% | 2089.78 | 256 / 258 | 70% | 5.66 | 161 / 230 |
| liver | 70% | 881.03 | 159 / 226 | 66% | 7.02 | 269 / 406 |
| adipose | 100% | 4264.36 | 1204 / 1204 | 0% | 0 | 0 / 0 |
| blood vessel | 100% | 4268.24 | 1335 / 1335 | 0% | 0 | 0 / 0 |
| eye | 0% | 0 | 0 / 0 | 100% | 27.38 | 80 / 80 |
| spleen | 100% | 2837.17 | 241 / 241 | 0% | 0 | 0 / 0 |
| muscle | 98% | 1844.57 | 786 / 803 | 0% | 0 | 0 / 0 |
| peripheral blood | 95% | 2939.45 | 887 / 929 | 0% | 0 | 0 / 0 |
| tonsil | 0% | 0 | 0 / 0 | 93% | 24.19 | 42 / 45 |
| heart | 89% | 1804.24 | 767 / 861 | 0% | 0 | 0 / 0 |
| lymph node | 0% | 0 | 0 / 0 | 83% | 13.16 | 24 / 29 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
| GO_0007165 | Biological process | signal transduction |
| GO_0009267 | Biological process | cellular response to starvation |
| GO_0048679 | Biological process | regulation of axon regeneration |
| GO_0034599 | Biological process | cellular response to oxidative stress |
| GO_0048680 | Biological process | positive regulation of axon regeneration |
| GO_0097194 | Biological process | execution phase of apoptosis |
| GO_0030336 | Biological process | negative regulation of cell migration |
| GO_0006468 | Biological process | protein phosphorylation |
| GO_0008631 | Biological process | intrinsic apoptotic signaling pathway in response to oxidative stress |
| GO_0046777 | Biological process | protein autophosphorylation |
| GO_0005730 | Cellular component | nucleolus |
| GO_0090443 | Cellular component | FAR/SIN/STRIPAK complex |
| GO_0070062 | Cellular component | extracellular exosome |
| GO_0005654 | Cellular component | nucleoplasm |
| GO_0005794 | Cellular component | Golgi apparatus |
| GO_0000139 | Cellular component | Golgi membrane |
| GO_0005829 | Cellular component | cytosol |
| GO_0005737 | Cellular component | cytoplasm |
| GO_0005634 | Cellular component | nucleus |
| GO_0106310 | Molecular function | protein serine kinase activity |
| GO_0045296 | Molecular function | cadherin binding |
| GO_0004674 | Molecular function | protein serine/threonine kinase activity |
| GO_0004672 | Molecular function | protein kinase activity |
| GO_0046872 | Molecular function | metal ion binding |
| GO_0005524 | Molecular function | ATP binding |
| GO_0005515 | Molecular function | protein binding |
| Gene name | STK24 |
| Protein name | Alternative protein STK24 non-specific serine/threonine protein kinase (EC 2.7.11.1) Serine/threonine kinase 24 Serine/threonine-protein kinase 24 (EC 2.7.11.1) (Mammalian STE20-like protein kinase 3) (MST-3) (STE20-like kinase MST3) [Cleaved into: Serine/threonine-protein kinase 24 36 kDa subunit (Mammalian STE20-like protein kinase 3 N-terminal) (MST3/N); Serine/threonine-protein kinase 24 12 kDa subunit (Mammalian STE20-like protein kinase 3 C-terminal) (MST3/C)] |
| Synonyms | HEL-S-95 hCG_27759 MST3 STK3 |
| Description | FUNCTION: Serine/threonine-protein kinase that acts on both serine and threonine residues and promotes apoptosis in response to stress stimuli and caspase activation. Mediates oxidative-stress-induced cell death by modulating phosphorylation of JNK1-JNK2 (MAPK8 and MAPK9), p38 (MAPK11, MAPK12, MAPK13 and MAPK14) during oxidative stress. Plays a role in a staurosporine-induced caspase-independent apoptotic pathway by regulating the nuclear translocation of AIFM1 and ENDOG and the DNase activity associated with ENDOG. Phosphorylates STK38L on 'Thr-442' and stimulates its kinase activity. In association with STK26 negatively regulates Golgi reorientation in polarized cell migration upon RHO activation . Regulates also cellular migration with alteration of PTPN12 activity and PXN phosphorylation: phosphorylates PTPN12 and inhibits its activity and may regulate PXN phosphorylation through PTPN12. May act as a key regulator of axon regeneration in the optic nerve and radial nerve. . |
| Accessions | ENST00000418038.5 ENST00000376554.8 ENST00000397517.6 H0Y630 ENST00000539966.6 [Q9Y6E0-2] Q6P0Y1 Q9Y6E0 B4DR80 ENST00000376547.7 [Q9Y6E0-1] L8E7H5 Q5JV99 Q5U0E6 Q5JV98 Q6FG81 ENST00000444574.1 |