Name | Number of supported studies | Average coverage | |
---|---|---|---|
endothelial cell | 49 studies | 61% ± 24% | |
fibroblast | 48 studies | 67% ± 23% | |
pericyte | 40 studies | 72% ± 22% | |
smooth muscle cell | 32 studies | 60% ± 20% | |
connective tissue cell | 19 studies | 75% ± 21% | |
capillary endothelial cell | 18 studies | 65% ± 23% | |
endothelial cell of vascular tree | 15 studies | 57% ± 22% | |
endothelial cell of artery | 14 studies | 50% ± 24% | |
myofibroblast cell | 14 studies | 77% ± 18% | |
vein endothelial cell | 14 studies | 56% ± 21% | |
astrocyte | 12 studies | 42% ± 22% | |
platelet | 10 studies | 70% ± 14% | |
mesothelial cell | 10 studies | 78% ± 25% | |
adipocyte | 10 studies | 52% ± 24% | |
oligodendrocyte | 9 studies | 25% ± 8% | |
type I pneumocyte | 8 studies | 42% ± 23% | |
epithelial cell | 8 studies | 40% ± 21% | |
oligodendrocyte precursor cell | 7 studies | 34% ± 19% | |
macrophage | 6 studies | 36% ± 24% | |
glial cell | 6 studies | 71% ± 22% | |
endothelial cell of lymphatic vessel | 6 studies | 37% ± 12% | |
endothelial cell of sinusoid | 5 studies | 40% ± 30% | |
progenitor cell | 5 studies | 44% ± 26% | |
abnormal cell | 5 studies | 48% ± 28% | |
adventitial cell | 5 studies | 63% ± 25% | |
T cell | 4 studies | 44% ± 31% | |
glomerular endothelial cell | 4 studies | 92% ± 3% | |
epithelial cell of proximal tubule | 4 studies | 34% ± 13% | |
Schwann cell | 4 studies | 64% ± 24% | |
basal cell | 4 studies | 44% ± 22% | |
chondrocyte | 4 studies | 63% ± 20% | |
hepatic stellate cell | 3 studies | 30% ± 12% | |
podocyte | 3 studies | 89% ± 7% | |
neural crest cell | 3 studies | 75% ± 2% | |
retinal bipolar neuron | 3 studies | 26% ± 6% | |
extravillous trophoblast | 3 studies | 50% ± 8% | |
megakaryocyte | 3 studies | 49% ± 17% | |
retinal pigment epithelial cell | 3 studies | 39% ± 30% | |
myeloid cell | 3 studies | 25% ± 11% | |
myoepithelial cell | 3 studies | 66% ± 26% | |
neuron | 3 studies | 32% ± 10% | |
muscle cell | 3 studies | 37% ± 15% | |
melanocyte | 3 studies | 53% ± 26% |
Name | Number of supported studies | Average coverage | |
---|---|---|---|
lung | 8 studies | 38% ± 21% | |
brain | 7 studies | 30% ± 21% | |
intestine | 5 studies | 51% ± 9% | |
eye | 5 studies | 27% ± 11% | |
heart | 5 studies | 28% ± 9% | |
uterus | 5 studies | 35% ± 4% | |
adipose | 5 studies | 39% ± 29% | |
kidney | 4 studies | 36% ± 12% | |
skin | 4 studies | 34% ± 12% | |
breast | 4 studies | 26% ± 5% | |
placenta | 3 studies | 42% ± 3% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
breast | 100% | 95533.54 | 458 / 459 | 97% | 2105.64 | 1084 / 1118 |
thymus | 99% | 51919.14 | 648 / 653 | 87% | 778.24 | 526 / 605 |
lung | 100% | 86784.73 | 577 / 578 | 86% | 862.02 | 992 / 1155 |
skin | 89% | 71802.47 | 1605 / 1809 | 96% | 1435.55 | 451 / 472 |
adrenal gland | 99% | 56537.80 | 255 / 258 | 83% | 1205.20 | 192 / 230 |
kidney | 91% | 33487.69 | 81 / 89 | 83% | 1309.47 | 744 / 901 |
brain | 74% | 45119.91 | 1960 / 2642 | 99% | 3428.28 | 697 / 705 |
bladder | 100% | 47834.38 | 21 / 21 | 72% | 688.14 | 364 / 504 |
ovary | 96% | 48416.51 | 173 / 180 | 72% | 788.75 | 311 / 430 |
uterus | 99% | 72814.39 | 168 / 170 | 58% | 723.82 | 264 / 459 |
intestine | 80% | 43999.88 | 771 / 966 | 71% | 687.36 | 375 / 527 |
prostate | 95% | 40961.69 | 233 / 245 | 50% | 266.78 | 252 / 502 |
esophagus | 69% | 31089.93 | 1004 / 1445 | 62% | 511.81 | 114 / 183 |
stomach | 44% | 15353.77 | 157 / 359 | 75% | 700.01 | 215 / 286 |
adipose | 100% | 130714.43 | 1204 / 1204 | 0% | 0 | 0 / 0 |
blood vessel | 100% | 166418.51 | 1332 / 1335 | 0% | 0 | 0 / 0 |
pancreas | 4% | 1375.05 | 12 / 328 | 96% | 1908.31 | 170 / 178 |
heart | 92% | 48026.06 | 794 / 861 | 0% | 0 | 0 / 0 |
spleen | 88% | 29379.56 | 212 / 241 | 0% | 0 | 0 / 0 |
lymph node | 0% | 0 | 0 / 0 | 59% | 323.86 | 17 / 29 |
tonsil | 0% | 0 | 0 / 0 | 58% | 551.33 | 26 / 45 |
liver | 6% | 1690.65 | 14 / 226 | 35% | 204.23 | 143 / 406 |
muscle | 34% | 8752.49 | 277 / 803 | 0% | 0 | 0 / 0 |
eye | 0% | 0 | 0 / 0 | 34% | 155.76 | 27 / 80 |
peripheral blood | 4% | 783.50 | 33 / 929 | 0% | 0 | 0 / 0 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
GO_0022604 | Biological process | regulation of cell morphogenesis |
GO_0010595 | Biological process | positive regulation of endothelial cell migration |
GO_0016525 | Biological process | negative regulation of angiogenesis |
GO_0001937 | Biological process | negative regulation of endothelial cell proliferation |
GO_0048856 | Biological process | anatomical structure development |
GO_0005615 | Cellular component | extracellular space |
GO_0031091 | Cellular component | platelet alpha granule |
GO_0005576 | Cellular component | extracellular region |
GO_0005886 | Cellular component | plasma membrane |
GO_0005739 | Cellular component | mitochondrion |
GO_0071682 | Cellular component | endocytic vesicle lumen |
GO_0062023 | Cellular component | collagen-containing extracellular matrix |
GO_0031092 | Cellular component | platelet alpha granule membrane |
GO_0016363 | Cellular component | nuclear matrix |
GO_0009986 | Cellular component | cell surface |
GO_0031093 | Cellular component | platelet alpha granule lumen |
GO_0005737 | Cellular component | cytoplasm |
GO_0043231 | Cellular component | intracellular membrane-bounded organelle |
GO_0005604 | Cellular component | basement membrane |
GO_0005201 | Molecular function | extracellular matrix structural constituent |
GO_0050840 | Molecular function | extracellular matrix binding |
GO_0005509 | Molecular function | calcium ion binding |
GO_0005518 | Molecular function | collagen binding |
GO_0005515 | Molecular function | protein binding |
Gene name | SPARC |
Protein name | Secreted protein acidic and cysteine rich Cysteine-rich protein SPARC (Basement-membrane protein 40) (BM-40) (Osteonectin) (ON) (Secreted protein acidic and rich in cysteine) |
Synonyms | ON |
Description | FUNCTION: Appears to regulate cell growth through interactions with the extracellular matrix and cytokines. Binds calcium and copper, several types of collagen, albumin, thrombospondin, PDGF and cell membranes. There are two calcium binding sites; an acidic domain that binds 5 to 8 Ca(2+) with a low affinity and an EF-hand loop that binds a Ca(2+) ion with a high affinity. |
Accessions | ENST00000539687.6 ENST00000538026.5 ENST00000522348.1 E5RJA5 E5RK62 F5H4E2 Q6QE20 ENST00000521569.1 P09486 F5GY03 ENST00000231061.9 |