SP140L report

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I. Expression across cell types

Cell ontologyData table

Name	Number of supported studies	Average coverage
B cell	21 studies	23% ± 7%	Explore
naive B cell	16 studies	25% ± 5%	Explore
memory B cell	11 studies	18% ± 2%	Explore
natural killer cell	9 studies	19% ± 3%	Explore
CD4-positive, alpha-beta T cell	9 studies	22% ± 7%	Explore
T cell	7 studies	17% ± 1%	Explore
CD16-negative, CD56-bright natural killer cell, human	7 studies	20% ± 3%	Explore
naive thymus-derived CD4-positive, alpha-beta T cell	6 studies	20% ± 4%	Explore
CD16-positive, CD56-dim natural killer cell, human	6 studies	18% ± 3%	Explore
CD8-positive, alpha-beta T cell	6 studies	24% ± 5%	Explore
mucosal invariant T cell	6 studies	18% ± 2%	Explore
macrophage	6 studies	21% ± 4%	Explore
gamma-delta T cell	6 studies	21% ± 6%	Explore
naive thymus-derived CD8-positive, alpha-beta T cell	5 studies	22% ± 6%	Explore
microglial cell	5 studies	23% ± 5%	Explore
CD4-positive, alpha-beta memory T cell	5 studies	18% ± 3%	Explore
effector memory CD8-positive, alpha-beta T cell	4 studies	24% ± 8%	Explore
precursor B cell	4 studies	19% ± 1%	Explore
immature B cell	4 studies	27% ± 5%	Explore
endothelial cell	4 studies	19% ± 2%	Explore
non-classical monocyte	3 studies	22% ± 4%	Explore
lymphocyte	3 studies	27% ± 4%	Explore
effector memory CD4-positive, alpha-beta T cell	3 studies	22% ± 7%	Explore
monocyte	3 studies	15% ± 0%	Explore
CD8-positive, alpha-beta memory T cell	3 studies	21% ± 5%	Explore
regulatory T cell	3 studies	18% ± 2%	Explore
double negative thymocyte	3 studies	18% ± 2%	Explore

II. Expression across tissues

sc-RNAseq dataData table

Name	Number of supported studies	Average coverage
peripheral blood	4 studies	22% ± 4%	Explore

Bulk RNAseq dataData table

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
lung	100%	1803.18	578 / 578	100%	14.22	1152 / 1155
esophagus	100%	833.48	1444 / 1445	99%	15.81	181 / 183
kidney	100%	934.46	89 / 89	98%	9.26	880 / 901
bladder	100%	1081.19	21 / 21	97%	11.54	491 / 504
stomach	100%	724.14	359 / 359	97%	10.78	277 / 286
liver	100%	1091.31	226 / 226	96%	7.65	391 / 406
uterus	100%	1146.12	170 / 170	96%	10.39	442 / 459
intestine	100%	1389.02	966 / 966	96%	10.63	507 / 527
breast	100%	1297.86	459 / 459	95%	9.80	1061 / 1118
thymus	100%	922.35	652 / 653	94%	6.68	570 / 605
ovary	100%	1403.37	180 / 180	94%	8.38	404 / 430
pancreas	90%	369.21	295 / 328	97%	14.09	172 / 178
skin	94%	746.93	1707 / 1809	88%	10.13	413 / 472
prostate	100%	1137.98	245 / 245	79%	4.00	398 / 502
adrenal gland	100%	1376.90	258 / 258	63%	4.01	144 / 230
adipose	100%	1305.99	1204 / 1204	0%	0	0 / 0
lymph node	0%	0	0 / 0	100%	20.95	29 / 29
spleen	100%	4014.71	241 / 241	0%	0	0 / 0
ureter	0%	0	0 / 0	100%	7.92	1 / 1
blood vessel	100%	748.80	1333 / 1335	0%	0	0 / 0
peripheral blood	99%	1564.82	921 / 929	0%	0	0 / 0
brain	32%	98.00	856 / 2642	66%	3.92	464 / 705
heart	97%	468.34	835 / 861	0%	0	0 / 0
tonsil	0%	0	0 / 0	96%	10.23	43 / 45
muscle	90%	379.42	724 / 803	0%	0	0 / 0
eye	0%	0	0 / 0	30%	1.23	24 / 80
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
gingiva	0%	0	0 / 0	0%	0	0 / 0
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0