Name | Number of supported studies | Average coverage | |
---|---|---|---|
endothelial cell | 37 studies | 40% ± 17% | |
smooth muscle cell | 24 studies | 40% ± 19% | |
ciliated cell | 18 studies | 37% ± 17% | |
pericyte | 18 studies | 41% ± 20% | |
glutamatergic neuron | 12 studies | 70% ± 23% | |
oligodendrocyte precursor cell | 12 studies | 39% ± 18% | |
GABAergic neuron | 11 studies | 57% ± 23% | |
endothelial cell of artery | 11 studies | 23% ± 7% | |
mesothelial cell | 10 studies | 40% ± 19% | |
astrocyte | 9 studies | 35% ± 20% | |
neuron | 8 studies | 44% ± 23% | |
retinal cone cell | 8 studies | 72% ± 18% | |
retinal rod cell | 8 studies | 73% ± 19% | |
glial cell | 7 studies | 36% ± 16% | |
epithelial cell | 7 studies | 43% ± 18% | |
club cell | 7 studies | 33% ± 13% | |
fibroblast | 7 studies | 36% ± 16% | |
cardiac muscle cell | 7 studies | 83% ± 24% | |
basal cell | 7 studies | 27% ± 11% | |
hepatocyte | 6 studies | 67% ± 24% | |
capillary endothelial cell | 6 studies | 38% ± 16% | |
interneuron | 6 studies | 67% ± 10% | |
vein endothelial cell | 6 studies | 24% ± 5% | |
Mueller cell | 6 studies | 79% ± 17% | |
type I pneumocyte | 6 studies | 24% ± 4% | |
type II pneumocyte | 6 studies | 36% ± 9% | |
retinal bipolar neuron | 5 studies | 32% ± 16% | |
mucus secreting cell | 5 studies | 46% ± 26% | |
endothelial cell of vascular tree | 5 studies | 33% ± 10% | |
duct epithelial cell | 4 studies | 41% ± 23% | |
respiratory goblet cell | 4 studies | 38% ± 21% | |
cholangiocyte | 4 studies | 77% ± 6% | |
granule cell | 4 studies | 38% ± 20% | |
microglial cell | 4 studies | 46% ± 21% | |
retinal pigment epithelial cell | 4 studies | 62% ± 14% | |
secretory cell | 4 studies | 23% ± 5% | |
pancreatic A cell | 3 studies | 34% ± 7% | |
type B pancreatic cell | 3 studies | 34% ± 15% | |
glomerular endothelial cell | 3 studies | 30% ± 3% | |
epithelial cell of proximal tubule | 3 studies | 41% ± 19% | |
GABAergic interneuron | 3 studies | 55% ± 5% | |
Purkinje cell | 3 studies | 78% ± 14% | |
squamous epithelial cell | 3 studies | 38% ± 18% | |
amacrine cell | 3 studies | 27% ± 1% | |
GABAergic amacrine cell | 3 studies | 48% ± 20% | |
OFF-bipolar cell | 3 studies | 54% ± 21% | |
adipocyte | 3 studies | 23% ± 10% | |
muscle cell | 3 studies | 55% ± 30% | |
pancreatic ductal cell | 3 studies | 61% ± 17% | |
ependymal cell | 3 studies | 38% ± 3% | |
enteroendocrine cell | 3 studies | 31% ± 11% | |
Schwann cell | 3 studies | 53% ± 8% | |
transit amplifying cell | 3 studies | 27% ± 10% | |
goblet cell | 3 studies | 24% ± 8% | |
oligodendrocyte | 3 studies | 34% ± 18% | |
kidney loop of Henle epithelial cell | 3 studies | 24% ± 9% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
thymus | 100% | 14926.68 | 650 / 653 | 97% | 31.32 | 586 / 605 |
prostate | 96% | 7830.24 | 234 / 245 | 100% | 20.84 | 501 / 502 |
adrenal gland | 100% | 23791.80 | 258 / 258 | 95% | 29.41 | 218 / 230 |
pancreas | 99% | 6999.95 | 326 / 328 | 89% | 12.94 | 159 / 178 |
liver | 94% | 5369.02 | 212 / 226 | 93% | 15.36 | 376 / 406 |
breast | 86% | 4189.56 | 393 / 459 | 78% | 11.34 | 868 / 1118 |
kidney | 64% | 2172.12 | 57 / 89 | 91% | 14.80 | 824 / 901 |
stomach | 92% | 7092.93 | 329 / 359 | 61% | 5.02 | 174 / 286 |
intestine | 80% | 11483.05 | 771 / 966 | 60% | 4.69 | 315 / 527 |
bladder | 95% | 12171.62 | 20 / 21 | 39% | 3.07 | 198 / 504 |
esophagus | 81% | 7085.13 | 1170 / 1445 | 48% | 3.58 | 87 / 183 |
brain | 59% | 2617.09 | 1568 / 2642 | 61% | 4.29 | 428 / 705 |
blood vessel | 99% | 32236.88 | 1326 / 1335 | 0% | 0 | 0 / 0 |
heart | 96% | 27355.63 | 828 / 861 | 0% | 0 | 0 / 0 |
lung | 41% | 1318.59 | 239 / 578 | 45% | 4.64 | 515 / 1155 |
uterus | 48% | 1925.26 | 82 / 170 | 37% | 3.83 | 170 / 459 |
adipose | 77% | 3818.07 | 925 / 1204 | 0% | 0 | 0 / 0 |
ovary | 35% | 1455.65 | 63 / 180 | 39% | 2.35 | 166 / 430 |
spleen | 67% | 2502.50 | 161 / 241 | 0% | 0 | 0 / 0 |
skin | 14% | 459.28 | 260 / 1809 | 44% | 5.56 | 208 / 472 |
tonsil | 0% | 0 | 0 / 0 | 33% | 2.69 | 15 / 45 |
eye | 0% | 0 | 0 / 0 | 33% | 2.69 | 26 / 80 |
muscle | 10% | 363.68 | 77 / 803 | 0% | 0 | 0 / 0 |
lymph node | 0% | 0 | 0 / 0 | 3% | 0.16 | 1 / 29 |
peripheral blood | 1% | 28.07 | 10 / 929 | 0% | 0 | 0 / 0 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
GO_0007219 | Biological process | Notch signaling pathway |
GO_0061049 | Biological process | cell growth involved in cardiac muscle cell development |
GO_0007010 | Biological process | cytoskeleton organization |
GO_0008150 | Biological process | biological_process |
GO_0016324 | Cellular component | apical plasma membrane |
GO_0005886 | Cellular component | plasma membrane |
GO_0048471 | Cellular component | perinuclear region of cytoplasm |
GO_0030018 | Cellular component | Z disc |
GO_0043025 | Cellular component | neuronal cell body |
GO_0005925 | Cellular component | focal adhesion |
GO_0030425 | Cellular component | dendrite |
GO_0015629 | Cellular component | actin cytoskeleton |
GO_0045202 | Cellular component | synapse |
GO_0030027 | Cellular component | lamellipodium |
GO_0005634 | Cellular component | nucleus |
GO_0008307 | Molecular function | structural constituent of muscle |
GO_0005200 | Molecular function | structural constituent of cytoskeleton |
GO_0003723 | Molecular function | RNA binding |
GO_0008093 | Molecular function | cytoskeletal anchor activity |
GO_0005515 | Molecular function | protein binding |
Gene name | SORBS2 |
Protein name | Sorbin and SH3 domain-containing protein 2 (Arg-binding protein 2) (ArgBP2) (Arg/Abl-interacting protein 2) (Sorbin) Sorbin and SH3 domain-containing protein 2 Sorbin and SH3 domain containing 2 |
Synonyms | ARGBP2 KIAA0777 |
Description | FUNCTION: Adapter protein that plays a role in the assembling of signaling complexes, being a link between ABL kinases and actin cytoskeleton. Can form complex with ABL1 and CBL, thus promoting ubiquitination and degradation of ABL1. May play a role in the regulation of pancreatic cell adhesion, possibly by acting on WASF1 phosphorylation, enhancing phosphorylation by ABL1, as well as dephosphorylation by PTPN12 . Isoform 6 increases water and sodium absorption in the intestine and gall-bladder. . |
Accessions | ENST00000695410.1 ENST00000698537.1 A0A8V8TMC7 ENST00000445343.5 ENST00000487836.6 [O94875-7] C9JM25 O94875 ENST00000414724.5 C9J8E3 ENST00000698536.1 C9JEA9 ENST00000355634.9 [O94875-11] C9JFS9 C9JZ60 ENST00000393523.6 ENST00000487184.2 ENST00000490562.6 A0A8Q3WKK4 ENST00000445625.1 ENST00000452351.5 A0A3B3ITL8 ENST00000444771.5 ENST00000428330.5 C9JN77 ENST00000421420.6 ENST00000451974.6 [O94875-8] C9JC90 ENST00000415274.5 ENST00000498125.6 C9IZ89 ENST00000432655.5 A0A8Q3WKF2 ENST00000695409.1 ENST00000439049.5 ENST00000451958.5 ENST00000438278.5 A0A8V8TLU4 ENST00000698843.1 C9J9D3 C9J4Z9 ENST00000698540.1 H7BXR3 A0A8Q3SHW0 C9J348 ENST00000319471.13 [O94875-12] A0A8V8TNN1 C9J620 ENST00000319454.10 ENST00000650145.1 C9J3W4 A0A8V8TNC1 ENST00000419063.5 ENST00000284776.11 [O94875-1] ENST00000457247.5 H7BZX1 ENST00000393528.7 [O94875-2] C9JWC3 ENST00000437304.6 [O94875-10] C9JBR8 ENST00000450341.5 C9JLD6 ENST00000451974.5 ENST00000451701.5 C9J7Q5 C9IZT7 ENST00000695411.1 ENST00000439914.5 ENST00000456596.5 ENST00000420158.5 A0A8Q3WLK0 H7C1R7 A0A8V8TMD6 ENST00000421639.5 ENST00000425679.5 C9JDX2 C9JBB0 A0A8Q3WKH1 A0A9L9PXP6 C9JI79 A0A1D5RMN3 ENST00000429056.5 ENST00000430503.5 C9JL62 ENST00000449407.6 [O94875-9] H7BZK1 ENST00000457934.5 C9JG84 C9J4K2 ENST00000444781.5 A0A8Q3WLU7 ENST00000456060.5 ENST00000698539.1 ENST00000706921.1 ENST00000435480.5 ENST00000445115.5 C9J372 ENST00000431902.5 |