Name | Number of supported studies | Average coverage | |
---|---|---|---|
endothelial cell | 19 studies | 30% ± 14% | |
astrocyte | 14 studies | 39% ± 17% | |
microglial cell | 12 studies | 32% ± 12% | |
fibroblast | 11 studies | 26% ± 10% | |
oligodendrocyte | 11 studies | 38% ± 13% | |
glutamatergic neuron | 10 studies | 50% ± 25% | |
oligodendrocyte precursor cell | 10 studies | 41% ± 16% | |
adipocyte | 10 studies | 38% ± 12% | |
GABAergic neuron | 9 studies | 49% ± 24% | |
pericyte | 9 studies | 32% ± 15% | |
amacrine cell | 8 studies | 34% ± 12% | |
retinal rod cell | 7 studies | 26% ± 9% | |
epithelial cell | 7 studies | 31% ± 15% | |
macrophage | 7 studies | 35% ± 11% | |
retinal cone cell | 7 studies | 31% ± 14% | |
B cell | 6 studies | 21% ± 4% | |
endothelial cell of lymphatic vessel | 6 studies | 28% ± 12% | |
neuron | 6 studies | 39% ± 13% | |
interneuron | 6 studies | 56% ± 21% | |
retina horizontal cell | 6 studies | 40% ± 16% | |
smooth muscle cell | 6 studies | 26% ± 8% | |
retinal bipolar neuron | 5 studies | 25% ± 3% | |
cardiac muscle cell | 5 studies | 30% ± 7% | |
mast cell | 5 studies | 21% ± 5% | |
Mueller cell | 5 studies | 30% ± 15% | |
basal cell | 5 studies | 29% ± 19% | |
natural killer cell | 4 studies | 18% ± 2% | |
granule cell | 4 studies | 38% ± 7% | |
retinal ganglion cell | 4 studies | 26% ± 16% | |
dendritic cell | 4 studies | 19% ± 4% | |
ciliated cell | 4 studies | 24% ± 5% | |
lymphocyte | 4 studies | 23% ± 7% | |
myeloid cell | 4 studies | 18% ± 3% | |
connective tissue cell | 4 studies | 20% ± 4% | |
type I pneumocyte | 4 studies | 23% ± 8% | |
type II pneumocyte | 4 studies | 19% ± 6% | |
CD4-positive, alpha-beta T cell | 3 studies | 16% ± 1% | |
capillary endothelial cell | 3 studies | 16% ± 0% | |
GABAergic interneuron | 3 studies | 38% ± 3% | |
glial cell | 3 studies | 26% ± 7% | |
GABAergic amacrine cell | 3 studies | 39% ± 14% | |
OFF-bipolar cell | 3 studies | 33% ± 10% | |
ON-bipolar cell | 3 studies | 37% ± 11% | |
glycinergic amacrine cell | 3 studies | 37% ± 8% | |
rod bipolar cell | 3 studies | 33% ± 13% | |
endothelial cell of vascular tree | 3 studies | 27% ± 14% | |
hepatocyte | 3 studies | 40% ± 9% | |
ependymal cell | 3 studies | 41% ± 15% | |
myofibroblast cell | 3 studies | 24% ± 7% | |
T cell | 3 studies | 20% ± 3% | |
alveolar macrophage | 3 studies | 22% ± 6% | |
club cell | 3 studies | 24% ± 9% | |
monocyte | 3 studies | 22% ± 0% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
esophagus | 99% | 892.90 | 1433 / 1445 | 99% | 3.40 | 181 / 183 |
breast | 100% | 1282.25 | 459 / 459 | 84% | 2.88 | 936 / 1118 |
stomach | 100% | 752.82 | 358 / 359 | 83% | 2.28 | 236 / 286 |
lung | 100% | 772.89 | 578 / 578 | 79% | 1.94 | 907 / 1155 |
prostate | 100% | 752.64 | 245 / 245 | 76% | 2.29 | 382 / 502 |
brain | 91% | 523.40 | 2411 / 2642 | 82% | 2.31 | 578 / 705 |
intestine | 100% | 870.11 | 963 / 966 | 73% | 1.61 | 387 / 527 |
thymus | 100% | 1440.43 | 653 / 653 | 70% | 1.70 | 425 / 605 |
kidney | 100% | 532.62 | 89 / 89 | 67% | 1.82 | 608 / 901 |
skin | 100% | 1160.33 | 1807 / 1809 | 63% | 1.53 | 299 / 472 |
pancreas | 99% | 558.18 | 326 / 328 | 63% | 1.21 | 112 / 178 |
bladder | 100% | 960.33 | 21 / 21 | 56% | 1.38 | 280 / 504 |
uterus | 100% | 1412.63 | 170 / 170 | 54% | 1.18 | 250 / 459 |
ovary | 100% | 1878.84 | 180 / 180 | 44% | 0.80 | 188 / 430 |
adrenal gland | 100% | 761.94 | 258 / 258 | 41% | 0.72 | 95 / 230 |
liver | 84% | 270.10 | 190 / 226 | 17% | 0.28 | 70 / 406 |
blood vessel | 100% | 1056.47 | 1334 / 1335 | 0% | 0 | 0 / 0 |
adipose | 100% | 1158.42 | 1203 / 1204 | 0% | 0 | 0 / 0 |
muscle | 100% | 676.95 | 799 / 803 | 0% | 0 | 0 / 0 |
spleen | 99% | 575.95 | 239 / 241 | 0% | 0 | 0 / 0 |
heart | 91% | 557.33 | 785 / 861 | 0% | 0 | 0 / 0 |
tonsil | 0% | 0 | 0 / 0 | 60% | 1.62 | 27 / 45 |
lymph node | 0% | 0 | 0 / 0 | 48% | 1.00 | 14 / 29 |
peripheral blood | 32% | 418.12 | 298 / 929 | 0% | 0 | 0 / 0 |
eye | 0% | 0 | 0 / 0 | 26% | 0.46 | 21 / 80 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
GO_0006974 | Biological process | DNA damage response |
GO_0016567 | Biological process | protein ubiquitination |
GO_0006281 | Biological process | DNA repair |
GO_0000209 | Biological process | protein polyubiquitination |
GO_0006334 | Biological process | nucleosome assembly |
GO_0005654 | Cellular component | nucleoplasm |
GO_0000786 | Cellular component | nucleosome |
GO_0003677 | Molecular function | DNA binding |
GO_0004842 | Molecular function | ubiquitin-protein transferase activity |
GO_0061630 | Molecular function | ubiquitin protein ligase activity |
GO_0140658 | Molecular function | ATP-dependent chromatin remodeler activity |
GO_0004386 | Molecular function | helicase activity |
GO_0016787 | Molecular function | hydrolase activity |
GO_0031625 | Molecular function | ubiquitin protein ligase binding |
GO_0005515 | Molecular function | protein binding |
GO_0046872 | Molecular function | metal ion binding |
GO_0005524 | Molecular function | ATP binding |
Gene name | SHPRH |
Protein name | E3 ubiquitin-protein ligase SHPRH (EC 2.3.2.27) (EC 3.6.4.-) (RING-type E3 ubiquitin transferase SHPRH) (SNF2, histone-linker, PHD and RING finger domain-containing helicase) SNF2 histone linker PHD RING helicase |
Synonyms | KIAA2023 hCG_18061 |
Description | FUNCTION: E3 ubiquitin-protein ligase involved in DNA repair. Upon genotoxic stress, accepts ubiquitin from the UBE2N-UBE2V2 E2 complex and transfers it to 'Lys-164' of PCNA which had been monoubiquitinated by UBE2A/B-RAD18, promoting the formation of non-canonical poly-ubiquitin chains linked through 'Lys-63'. . |
Accessions | Q5JT88 ENST00000417762.5 H7C2W2 A0A0D9SFM0 ENST00000438092.6 [Q149N8-4] ENST00000367505.6 [Q149N8-1] ENST00000521977.1 ENST00000629427.2 ENST00000519632.5 [Q149N8-2] ENST00000275233.12 [Q149N8-1] H0YBI0 Q149N8 ENST00000433355.6 |