SH3YL1 report

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I. Expression across cell types

Cell ontologyData table

Name	Number of supported studies	Average coverage
epithelial cell	16 studies	39% ± 20%	Explore
basal cell	13 studies	36% ± 16%	Explore
ciliated cell	11 studies	30% ± 18%	Explore
naive thymus-derived CD4-positive, alpha-beta T cell	10 studies	23% ± 4%	Explore
type II pneumocyte	9 studies	27% ± 8%	Explore
CD4-positive, alpha-beta T cell	9 studies	23% ± 7%	Explore
oligodendrocyte	8 studies	28% ± 9%	Explore
secretory cell	7 studies	33% ± 14%	Explore
naive thymus-derived CD8-positive, alpha-beta T cell	7 studies	24% ± 6%	Explore
epithelial cell of proximal tubule	7 studies	41% ± 12%	Explore
endothelial cell	7 studies	25% ± 7%	Explore
glutamatergic neuron	6 studies	44% ± 27%	Explore
GABAergic neuron	6 studies	38% ± 20%	Explore
astrocyte	6 studies	29% ± 10%	Explore
goblet cell	6 studies	29% ± 13%	Explore
type I pneumocyte	5 studies	23% ± 6%	Explore
club cell	5 studies	23% ± 5%	Explore
kidney loop of Henle epithelial cell	5 studies	23% ± 5%	Explore
intestinal crypt stem cell	5 studies	24% ± 6%	Explore
fibroblast	5 studies	22% ± 5%	Explore
duct epithelial cell	4 studies	23% ± 6%	Explore
respiratory goblet cell	4 studies	24% ± 10%	Explore
enterocyte	4 studies	20% ± 2%	Explore
progenitor cell	4 studies	17% ± 2%	Explore
abnormal cell	4 studies	24% ± 7%	Explore
regulatory T cell	4 studies	20% ± 2%	Explore
luminal hormone-sensing cell of mammary gland	4 studies	20% ± 3%	Explore
oligodendrocyte precursor cell	4 studies	30% ± 9%	Explore
transit amplifying cell	4 studies	30% ± 20%	Explore
CD4-positive, alpha-beta memory T cell	4 studies	21% ± 4%	Explore
microglial cell	3 studies	19% ± 2%	Explore
placental villous trophoblast	3 studies	31% ± 9%	Explore
mucus secreting cell	3 studies	32% ± 4%	Explore
serous secreting cell	3 studies	30% ± 8%	Explore
effector memory CD4-positive, alpha-beta T cell	3 studies	22% ± 7%	Explore
pancreatic ductal cell	3 studies	49% ± 11%	Explore
CD8-positive, alpha-beta T cell	3 studies	23% ± 6%	Explore
neuron	3 studies	25% ± 12%	Explore
interneuron	3 studies	48% ± 21%	Explore

II. Expression across tissues

sc-RNAseq dataData table

Name	Number of supported studies	Average coverage
brain	7 studies	39% ± 19%	Explore
lung	6 studies	28% ± 17%	Explore
kidney	5 studies	24% ± 9%	Explore
intestine	3 studies	21% ± 6%	Explore

Bulk RNAseq dataData table

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
ovary	100%	3901.28	180 / 180	99%	16.40	427 / 430
pancreas	100%	5929.15	328 / 328	99%	21.62	176 / 178
brain	100%	2153.89	2636 / 2642	99%	12.02	698 / 705
breast	100%	2327.89	459 / 459	99%	20.26	1103 / 1118
thymus	100%	3220.89	653 / 653	99%	23.35	596 / 605
prostate	100%	2944.69	245 / 245	98%	23.25	493 / 502
intestine	100%	2024.91	966 / 966	98%	23.24	514 / 527
stomach	100%	4531.51	359 / 359	95%	19.73	273 / 286
bladder	100%	2519.19	21 / 21	95%	21.71	478 / 504
uterus	100%	2154.29	170 / 170	95%	18.18	434 / 459
lung	99%	2346.38	575 / 578	95%	16.05	1096 / 1155
kidney	100%	5697.63	89 / 89	93%	15.38	842 / 901
esophagus	99%	1964.56	1436 / 1445	94%	13.18	172 / 183
adrenal gland	100%	3611.39	258 / 258	88%	9.32	202 / 230
skin	100%	3409.53	1809 / 1809	52%	3.58	245 / 472
spleen	100%	1866.27	241 / 241	0%	0	0 / 0
ureter	0%	0	0 / 0	100%	17.66	1 / 1
blood vessel	99%	1339.01	1326 / 1335	0%	0	0 / 0
adipose	99%	1240.89	1195 / 1204	0%	0	0 / 0
tonsil	0%	0	0 / 0	98%	13.13	44 / 45
liver	71%	503.79	160 / 226	21%	5.23	84 / 406
heart	88%	955.57	755 / 861	0%	0	0 / 0
muscle	79%	614.25	636 / 803	0%	0	0 / 0
eye	0%	0	0 / 0	41%	2.70	33 / 80
peripheral blood	37%	410.09	343 / 929	0%	0	0 / 0
lymph node	0%	0	0 / 0	24%	1.45	7 / 29
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
gingiva	0%	0	0 / 0	0%	0	0 / 0
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0