RPGR report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_0060271Biological processcilium assembly
GO_0007601Biological processvisual perception
GO_0016567Biological processprotein ubiquitination
GO_0006511Biological processubiquitin-dependent protein catabolic process
GO_0006886Biological processintracellular protein transport
GO_0042073Biological processintraciliary transport
GO_0005813Cellular componentcentrosome
GO_0036064Cellular componentciliary basal body
GO_0036126Cellular componentsperm flagellum
GO_0005794Cellular componentGolgi apparatus
GO_0001750Cellular componentphotoreceptor outer segment
GO_0005737Cellular componentcytoplasm
GO_0061630Molecular functionubiquitin protein ligase activity
GO_0005085Molecular functionguanyl-nucleotide exchange factor activity
GO_0005515Molecular functionprotein binding
GO_0003723Molecular functionRNA binding

IV. Literature review

[source]
Gene nameRPGR
Protein nameX-linked retinitis pigmentosa GTPase regulator splice variant 9
Retinitis pigmentosa GTPase regulator isoform 1 (Retinitis pigmentosa GTPase regulator, isoform CRA_c)
Retinitis pigmentosa GTPase regulator isoform 2
X-linked retinitis pigmentosa GTPase regulator
X-linked retinitis pigmentosa GTPase regulator splice variant 7
X-linked retinitis pigmentosa GTPase regulator splice variant 8
Retinitis pigmentosa GTPase regulator
SynonymshCG_1811533
RP3
XLRP3
DescriptionFUNCTION: Could be a guanine-nucleotide releasing factor. Plays a role in ciliogenesis. Probably regulates cilia formation by regulating actin stress filaments and cell contractility. Plays an important role in photoreceptor integrity. May play a critical role in spermatogenesis and in intraflagellar transport processes (By similarity). May be involved in microtubule organization and regulation of transport in primary cilia. .

AccessionsENST00000642395.2 [Q92834-2]
ENST00000642558.1
ENST00000464437.1
ENST00000646020.1
ENST00000642373.1
A0A0S2Z4Y6
A0A2R8YF02
Q92834
ENST00000645124.1
ENST00000482855.5 [Q92834-3]
A0A9Y1MW53
A0A0S2Z4D6
A0A9Y1I0G0
ENST00000642739.1
ENST00000474584.5 [Q92834-5]
A0A2R8Y414
ENST00000644238.1
H7C4L1
ENST00000645032.1 [Q92834-6]
A0A2R8YDN2
Q9HD28
H7C4H4
A0A9Y1MWX5
A0A2R8Y838
A0A2R8Y4C9
ENST00000339363.7 [Q92834-1]
ENST00000647261.1
A0A2R8YFT6
A0A2R8YGY6
ENST00000494707.6
ENST00000644337.1 [Q92834-4]