Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| endothelial cell | 16 studies | 26% ± 14% | |
| microglial cell | 11 studies | 36% ± 15% | |
| astrocyte | 10 studies | 35% ± 18% | |
| fibroblast | 9 studies | 29% ± 14% | |
| macrophage | 9 studies | 36% ± 16% | |
| B cell | 8 studies | 23% ± 9% | |
| adipocyte | 7 studies | 34% ± 10% | |
| dendritic cell | 7 studies | 21% ± 3% | |
| pericyte | 7 studies | 27% ± 11% | |
| smooth muscle cell | 7 studies | 26% ± 7% | |
| GABAergic neuron | 7 studies | 41% ± 24% | |
| oligodendrocyte | 7 studies | 33% ± 15% | |
| oligodendrocyte precursor cell | 7 studies | 30% ± 13% | |
| glutamatergic neuron | 6 studies | 49% ± 27% | |
| naive B cell | 6 studies | 20% ± 5% | |
| mast cell | 6 studies | 25% ± 4% | |
| plasma cell | 5 studies | 36% ± 12% | |
| myeloid cell | 5 studies | 29% ± 6% | |
| monocyte | 5 studies | 29% ± 10% | |
| type I pneumocyte | 5 studies | 26% ± 10% | |
| interneuron | 5 studies | 44% ± 26% | |
| plasmacytoid dendritic cell | 5 studies | 23% ± 3% | |
| memory B cell | 4 studies | 18% ± 2% | |
| cardiac muscle cell | 4 studies | 20% ± 2% | |
| mesothelial cell | 4 studies | 31% ± 8% | |
| non-classical monocyte | 4 studies | 21% ± 4% | |
| endothelial cell of lymphatic vessel | 4 studies | 31% ± 10% | |
| classical monocyte | 3 studies | 18% ± 2% | |
| plasmablast | 3 studies | 38% ± 16% | |
| precursor B cell | 3 studies | 28% ± 8% | |
| pro-B cell | 3 studies | 28% ± 3% | |
| epithelial cell | 3 studies | 37% ± 22% | |
| alveolar macrophage | 3 studies | 31% ± 9% | |
| club cell | 3 studies | 22% ± 8% | |
| basal cell | 3 studies | 36% ± 26% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| esophagus | 100% | 3149.79 | 1445 / 1445 | 100% | 14.01 | 183 / 183 |
| lung | 100% | 3088.27 | 578 / 578 | 100% | 10.92 | 1150 / 1155 |
| breast | 100% | 2830.52 | 459 / 459 | 100% | 14.11 | 1113 / 1118 |
| thymus | 100% | 2621.94 | 653 / 653 | 99% | 10.53 | 600 / 605 |
| stomach | 100% | 1758.75 | 359 / 359 | 99% | 9.14 | 283 / 286 |
| intestine | 100% | 2416.95 | 966 / 966 | 99% | 7.65 | 521 / 527 |
| uterus | 100% | 3011.56 | 170 / 170 | 98% | 10.98 | 452 / 459 |
| bladder | 100% | 2597.14 | 21 / 21 | 98% | 8.31 | 494 / 504 |
| prostate | 100% | 2289.46 | 245 / 245 | 98% | 6.89 | 492 / 502 |
| kidney | 100% | 1464.92 | 89 / 89 | 98% | 10.41 | 883 / 901 |
| pancreas | 100% | 1589.56 | 328 / 328 | 98% | 8.29 | 174 / 178 |
| ovary | 100% | 2645.94 | 180 / 180 | 97% | 6.79 | 416 / 430 |
| skin | 100% | 3538.74 | 1809 / 1809 | 96% | 10.39 | 452 / 472 |
| adrenal gland | 100% | 1978.74 | 258 / 258 | 93% | 5.85 | 215 / 230 |
| brain | 93% | 1014.94 | 2454 / 2642 | 100% | 7.70 | 702 / 705 |
| liver | 100% | 1109.92 | 226 / 226 | 90% | 5.43 | 364 / 406 |
| adipose | 100% | 2963.80 | 1204 / 1204 | 0% | 0 | 0 / 0 |
| lymph node | 0% | 0 | 0 / 0 | 100% | 16.82 | 29 / 29 |
| muscle | 100% | 3158.78 | 803 / 803 | 0% | 0 | 0 / 0 |
| spleen | 100% | 2561.20 | 241 / 241 | 0% | 0 | 0 / 0 |
| tonsil | 0% | 0 | 0 / 0 | 100% | 13.06 | 45 / 45 |
| ureter | 0% | 0 | 0 / 0 | 100% | 3.03 | 1 / 1 |
| blood vessel | 100% | 2836.92 | 1334 / 1335 | 0% | 0 | 0 / 0 |
| heart | 96% | 1255.32 | 828 / 861 | 0% | 0 | 0 / 0 |
| eye | 0% | 0 | 0 / 0 | 90% | 7.37 | 72 / 80 |
| peripheral blood | 87% | 2603.71 | 804 / 929 | 0% | 0 | 0 / 0 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| GO_0003330 | Biological process | regulation of extracellular matrix constituent secretion |
| GO_0042147 | Biological process | retrograde transport, endosome to Golgi |
| GO_0042177 | Biological process | negative regulation of protein catabolic process |
| GO_1904888 | Biological process | cranial skeletal system development |
| GO_0006886 | Biological process | intracellular protein transport |
| GO_0043547 | Biological process | positive regulation of GTPase activity |
| GO_0032588 | Cellular component | trans-Golgi network membrane |
| GO_0000139 | Cellular component | Golgi membrane |
| GO_0032991 | Cellular component | protein-containing complex |
| GO_0005829 | Cellular component | cytosol |
| GO_0034066 | Cellular component | Ric1-Rgp1 guanyl-nucleotide exchange factor complex |
| GO_0016020 | Cellular component | membrane |
| GO_0005085 | Molecular function | guanyl-nucleotide exchange factor activity |
| GO_0005515 | Molecular function | protein binding |
| GO_0031267 | Molecular function | small GTPase binding |
| Gene name | RIC1 |
| Protein name | Protein RIC1 homolog Guanine nucleotide exchange factor subunit RIC1 (Connexin-43-interacting protein of 150 kDa) (Protein RIC1 homolog) (RAB6A-GEF complex partner protein 1) RIC1 homolog, RAB6A GEF complex partner 1 |
| Synonyms | KIAA1432 CIP150 |
| Description | FUNCTION: The RIC1-RGP1 complex acts as a guanine nucleotide exchange factor (GEF), which activates RAB6A by exchanging bound GDP for free GTP, and may thereby be required for efficient fusion of endosome-derived vesicles with the Golgi compartment . The RIC1-RGP1 complex participates in the recycling of mannose-6-phosphate receptors . Required for phosphorylation and localization of GJA1 . Is a regulator of procollagen transport and secretion, and is required for correct cartilage morphogenesis and development of the craniofacial skeleton . . |
| Accessions | Q4ADV7 ENST00000251879.10 [Q4ADV7-2] ENST00000418622.7 [Q4ADV7-3] ENST00000414202.7 [Q4ADV7-1] ENST00000545641.5 ENST00000545243.1 H0YFN7 H0YGC4 ENST00000490816.1 H0YFD4 |