RAB4A | OmnibusX

I. Expression across cell types

Name	Number of supported studies	Average coverage
ciliated cell	14 studies	30% ± 13%	Explore
basal cell	13 studies	31% ± 13%	Explore
B cell	11 studies	20% ± 4%	Explore
epithelial cell	10 studies	35% ± 19%	Explore
endothelial cell	10 studies	25% ± 8%	Explore
plasmacytoid dendritic cell	8 studies	25% ± 9%	Explore
astrocyte	8 studies	29% ± 9%	Explore
platelet	7 studies	29% ± 5%	Explore
fibroblast	7 studies	23% ± 7%	Explore
natural killer cell	7 studies	18% ± 3%	Explore
classical monocyte	6 studies	23% ± 6%	Explore
CD16-positive, CD56-dim natural killer cell, human	6 studies	18% ± 2%	Explore
conventional dendritic cell	6 studies	27% ± 15%	Explore
pericyte	6 studies	18% ± 3%	Explore
smooth muscle cell	6 studies	18% ± 2%	Explore
secretory cell	5 studies	25% ± 15%	Explore
myofibroblast cell	5 studies	21% ± 5%	Explore
macrophage	5 studies	20% ± 5%	Explore
hematopoietic precursor cell	4 studies	27% ± 9%	Explore
pancreatic A cell	4 studies	27% ± 6%	Explore
non-classical monocyte	4 studies	32% ± 8%	Explore
CD4-positive, alpha-beta T cell	4 studies	18% ± 4%	Explore
progenitor cell	4 studies	22% ± 5%	Explore
intestinal crypt stem cell	4 studies	23% ± 4%	Explore
CD8-positive, alpha-beta T cell	4 studies	19% ± 3%	Explore
connective tissue cell	4 studies	22% ± 4%	Explore
retinal cone cell	4 studies	36% ± 14%	Explore
retinal rod cell	4 studies	22% ± 6%	Explore
neuron	4 studies	32% ± 12%	Explore
glutamatergic neuron	4 studies	41% ± 15%	Explore
abnormal cell	4 studies	27% ± 9%	Explore
oligodendrocyte	4 studies	27% ± 5%	Explore
hepatocyte	4 studies	36% ± 23%	Explore
retinal ganglion cell	3 studies	65% ± 19%	Explore
megakaryocyte	3 studies	35% ± 14%	Explore
duct epithelial cell	3 studies	19% ± 1%	Explore
mucus secreting cell	3 studies	43% ± 14%	Explore
luminal cell of prostate epithelium	3 studies	25% ± 7%	Explore
GABAergic neuron	3 studies	38% ± 4%	Explore
dendritic cell	3 studies	43% ± 16%	Explore
megakaryocyte-erythroid progenitor cell	3 studies	31% ± 20%	Explore
brush cell	3 studies	36% ± 19%	Explore
hematopoietic stem cell	3 studies	22% ± 6%	Explore
naive B cell	3 studies	19% ± 2%	Explore
luminal hormone-sensing cell of mammary gland	3 studies	17% ± 0%	Explore
myoepithelial cell	3 studies	28% ± 2%	Explore
oligodendrocyte precursor cell	3 studies	26% ± 4%	Explore

II. Expression across tissues

Name	Number of supported studies	Average coverage
lung	7 studies	25% ± 13%	Explore
intestine	6 studies	20% ± 8%	Explore
brain	6 studies	30% ± 11%	Explore
peripheral blood	5 studies	22% ± 5%	Explore
pancreas	3 studies	29% ± 5%	Explore
eye	3 studies	26% ± 5%	Explore
liver	3 studies	31% ± 10%	Explore

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
brain	100%	2599.88	2642 / 2642	100%	63.18	705 / 705
esophagus	100%	3224.87	1445 / 1445	100%	35.86	183 / 183
pancreas	100%	1983.23	328 / 328	100%	44.13	178 / 178
prostate	100%	3050.31	245 / 245	100%	101.45	502 / 502
stomach	100%	3215.07	359 / 359	100%	43.55	286 / 286
breast	100%	1963.63	459 / 459	100%	59.90	1117 / 1118
intestine	100%	2345.85	966 / 966	100%	48.20	526 / 527
uterus	100%	1504.51	170 / 170	100%	51.22	458 / 459
ovary	100%	1699.81	180 / 180	100%	43.55	429 / 430
liver	100%	1590.04	226 / 226	100%	54.88	405 / 406
thymus	100%	1836.91	652 / 653	100%	58.64	604 / 605
bladder	100%	2138.90	21 / 21	100%	43.47	502 / 504
skin	100%	2372.21	1808 / 1809	99%	42.91	469 / 472
lung	99%	1376.17	575 / 578	100%	42.96	1153 / 1155
kidney	100%	1550.99	89 / 89	98%	35.97	885 / 901
adrenal gland	100%	1574.22	258 / 258	94%	34.73	216 / 230
adipose	100%	1791.20	1204 / 1204	0%	0	0 / 0
blood vessel	100%	2502.32	1335 / 1335	0%	0	0 / 0
lymph node	0%	0	0 / 0	100%	32.88	29 / 29
spleen	100%	1024.43	241 / 241	0%	0	0 / 0
tonsil	0%	0	0 / 0	100%	42.08	45 / 45
ureter	0%	0	0 / 0	100%	32.95	1 / 1
muscle	100%	2153.57	802 / 803	0%	0	0 / 0
eye	0%	0	0 / 0	98%	32.66	78 / 80
heart	96%	2462.16	829 / 861	0%	0	0 / 0
peripheral blood	65%	585.81	602 / 929	0%	0	0 / 0
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
gingiva	0%	0	0 / 0	0%	0	0 / 0
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0

III. Associated gene sets

GO_0019882	Biological process	antigen processing and presentation
GO_0015031	Biological process	protein transport
GO_0016192	Biological process	vesicle-mediated transport
GO_0032482	Biological process	Rab protein signal transduction
GO_0030100	Biological process	regulation of endocytosis
GO_0098837	Cellular component	postsynaptic recycling endosome
GO_0031901	Cellular component	early endosome membrane
GO_0070062	Cellular component	extracellular exosome
GO_0055038	Cellular component	recycling endosome membrane
GO_0031982	Cellular component	vesicle
GO_0032593	Cellular component	insulin-responsive compartment
GO_0030659	Cellular component	cytoplasmic vesicle membrane
GO_0048471	Cellular component	perinuclear region of cytoplasm
GO_0019003	Molecular function	GDP binding
GO_0005525	Molecular function	GTP binding
GO_0005515	Molecular function	protein binding
GO_0003925	Molecular function	G protein activity
GO_0003924	Molecular function	GTPase activity

IV. Literature review

[source]

Gene name	RAB4A
Protein name	Ras-related protein Rab-4A (EC 3.6.5.2) Ras-related protein Rab-4A RAB4A, member RAS oncogene family
Synonyms	RAB4
Description	FUNCTION: Small GTPase which cycles between an active GTP-bound and an inactive GDP-bound state . Involved in protein transport . Plays a role in vesicular traffic. Mediates VEGFR2 endosomal trafficking to enhance VEGFR2 signaling . Acts as a regulator of platelet alpha-granule release during activation and aggregation of platelets (By similarity). .
Accessions	P20338 ENST00000618010.4 A0A087WYT5 ENST00000366690.5 A0A023HJ61

RAB4A report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

IV. Literature review