RAB3IP | OmnibusX

I. Expression across cell types

Name	Number of supported studies	Average coverage
oligodendrocyte precursor cell	13 studies	46% ± 23%	Explore
ciliated cell	9 studies	25% ± 11%	Explore
epithelial cell	8 studies	36% ± 20%	Explore
oligodendrocyte	8 studies	34% ± 10%	Explore
type I pneumocyte	7 studies	18% ± 3%	Explore
GABAergic neuron	6 studies	52% ± 18%	Explore
retinal rod cell	6 studies	22% ± 4%	Explore
retinal bipolar neuron	5 studies	43% ± 11%	Explore
retinal cone cell	5 studies	40% ± 12%	Explore
retinal pigment epithelial cell	5 studies	49% ± 13%	Explore
Mueller cell	5 studies	29% ± 7%	Explore
glutamatergic neuron	4 studies	42% ± 16%	Explore
ON-bipolar cell	4 studies	37% ± 17%	Explore
retinal ganglion cell	4 studies	30% ± 16%	Explore
kidney loop of Henle epithelial cell	4 studies	24% ± 3%	Explore
interneuron	4 studies	48% ± 21%	Explore
ionocyte	3 studies	26% ± 4%	Explore
pancreatic A cell	3 studies	34% ± 18%	Explore
type B pancreatic cell	3 studies	45% ± 22%	Explore
kidney distal convoluted tubule epithelial cell	3 studies	23% ± 5%	Explore
epithelial cell of proximal tubule	3 studies	25% ± 2%	Explore
endothelial cell	3 studies	21% ± 6%	Explore
OFF-bipolar cell	3 studies	37% ± 16%	Explore
rod bipolar cell	3 studies	52% ± 4%	Explore
astrocyte	3 studies	26% ± 10%	Explore
type II pneumocyte	3 studies	19% ± 3%	Explore
pancreatic ductal cell	3 studies	46% ± 21%	Explore
abnormal cell	3 studies	17% ± 1%	Explore
enteroendocrine cell	3 studies	26% ± 10%	Explore
goblet cell	3 studies	17% ± 2%	Explore
intestinal crypt stem cell	3 studies	19% ± 2%	Explore
club cell	3 studies	17% ± 1%	Explore
renal principal cell	3 studies	26% ± 7%	Explore

II. Expression across tissues

Name	Number of supported studies	Average coverage
brain	9 studies	32% ± 12%	Explore
eye	8 studies	25% ± 6%	Explore
pancreas	3 studies	37% ± 15%	Explore

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
brain	100%	4167.87	2642 / 2642	99%	30.09	701 / 705
prostate	99%	1380.15	242 / 245	99%	14.01	497 / 502
kidney	100%	3312.25	89 / 89	94%	19.77	849 / 901
pancreas	100%	1515.18	328 / 328	90%	6.68	161 / 178
lung	99%	1288.13	571 / 578	90%	8.08	1039 / 1155
thymus	100%	1060.67	651 / 653	88%	5.31	531 / 605
stomach	91%	898.07	328 / 359	95%	8.75	273 / 286
intestine	82%	906.91	793 / 966	95%	8.88	503 / 527
esophagus	80%	453.04	1150 / 1445	93%	11.07	170 / 183
breast	78%	673.29	360 / 459	91%	9.27	1015 / 1118
bladder	76%	452.05	16 / 21	89%	8.78	447 / 504
adrenal gland	100%	1426.45	258 / 258	58%	3.91	133 / 230
uterus	66%	335.16	113 / 170	83%	6.38	379 / 459
liver	96%	610.58	216 / 226	49%	3.90	198 / 406
ovary	44%	210.33	79 / 180	93%	7.85	400 / 430
spleen	100%	780.34	241 / 241	0%	0	0 / 0
ureter	0%	0	0 / 0	100%	5.49	1 / 1
skin	79%	735.08	1437 / 1809	17%	1.68	82 / 472
blood vessel	95%	709.04	1266 / 1335	0%	0	0 / 0
heart	89%	873.46	764 / 861	0%	0	0 / 0
tonsil	0%	0	0 / 0	82%	5.47	37 / 45
muscle	80%	717.10	641 / 803	0%	0	0 / 0
peripheral blood	59%	541.76	549 / 929	0%	0	0 / 0
adipose	52%	244.51	629 / 1204	0%	0	0 / 0
lymph node	0%	0	0 / 0	52%	2.62	15 / 29
eye	0%	0	0 / 0	3%	0.17	2 / 80
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
gingiva	0%	0	0 / 0	0%	0	0 / 0
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0

III. Associated gene sets

GO_0060271	Biological process	cilium assembly
GO_0006612	Biological process	protein targeting to membrane
GO_0006887	Biological process	exocytosis
GO_0045724	Biological process	positive regulation of cilium assembly
GO_0051490	Biological process	negative regulation of filopodium assembly
GO_0015031	Biological process	protein transport
GO_0097711	Biological process	ciliary basal body-plasma membrane docking
GO_0120229	Biological process	protein localization to motile cilium
GO_0048471	Cellular component	perinuclear region of cytoplasm
GO_0005813	Cellular component	centrosome
GO_0005634	Cellular component	nucleus
GO_0070319	Cellular component	Golgi to plasma membrane transport vesicle
GO_1990635	Cellular component	proximal dendrite
GO_0032588	Cellular component	trans-Golgi network membrane
GO_0005829	Cellular component	cytosol
GO_0030027	Cellular component	lamellipodium
GO_0005085	Molecular function	guanyl-nucleotide exchange factor activity
GO_0051020	Molecular function	GTPase binding
GO_0005515	Molecular function	protein binding

IV. Literature review

[source]

Gene name	RAB3IP
Protein name	RAB3A interacting protein Rab-3A-interacting protein (Rab3A-interacting protein) (Rabin-3) (Rabin8) (SSX2-interacting protein)
Synonyms	RABIN8
Description	FUNCTION: Guanine nucleotide exchange factor (GEF) which may activate RAB8A and RAB8B . Promotes the exchange of GDP to GTP, converting inactive GDP-bound Rab proteins into their active GTP-bound form . Mediates the release of GDP from RAB8A and RAB8B but not from RAB3A or RAB5 . Modulates actin organization and promotes polarized transport of RAB8A-specific vesicles to the cell surface . Together with RAB11A, RAB8A, the exocyst complex, PARD3, PRKCI, ANXA2, CDC42 and DNMBP promotes transcytosis of PODXL to the apical membrane initiation sites (AMIS), apical surface formation and lumenogenesis . Part of the ciliary targeting complex containing Rab11, ASAP1, RAB3IP and RAB11FIP3 and ARF4 that promotes RAB3IP preciliary vesicle trafficking to mother centriole and ciliogenesis initiation . .
Accessions	ENST00000549760.1 ENST00000547591.5 ENST00000547055.1 J3KPG1 ENST00000551641.5 [Q96QF0-8] F8VTR6 H0YI02 H0YI66 ENST00000553099.5 [Q96QF0-8] ENST00000552199.5 [Q96QF0-6] ENST00000550847.1 H0YHP4 ENST00000417413.7 [Q96QF0-5] ENST00000550647.5 ENST00000362025.9 [Q96QF0-4] ENST00000550536.5 [Q96QF0-1] F8VNX9 Q96QF0 ENST00000378809.8 ENST00000247833.12 [Q96QF0-2] ENST00000378815.10 [Q96QF0-7] H0YD03 ENST00000483530.6 [Q96QF0-3] ENST00000526994.6

RAB3IP report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

IV. Literature review