PTTG1IP | OmnibusX

I. Expression across cell types

Name	Number of supported studies	Average coverage
endothelial cell	45 studies	40% ± 17%	Explore
macrophage	33 studies	29% ± 9%	Explore
fibroblast	29 studies	28% ± 11%	Explore
conventional dendritic cell	21 studies	28% ± 13%	Explore
classical monocyte	21 studies	29% ± 10%	Explore
pericyte	20 studies	27% ± 10%	Explore
epithelial cell	19 studies	38% ± 20%	Explore
smooth muscle cell	18 studies	23% ± 5%	Explore
endothelial cell of lymphatic vessel	17 studies	38% ± 13%	Explore
non-classical monocyte	17 studies	26% ± 9%	Explore
ciliated cell	17 studies	40% ± 16%	Explore
monocyte	16 studies	25% ± 7%	Explore
basal cell	15 studies	32% ± 15%	Explore
astrocyte	15 studies	29% ± 12%	Explore
capillary endothelial cell	15 studies	38% ± 14%	Explore
connective tissue cell	14 studies	29% ± 10%	Explore
endothelial cell of artery	13 studies	46% ± 16%	Explore
dendritic cell	12 studies	30% ± 14%	Explore
myofibroblast cell	12 studies	23% ± 4%	Explore
vein endothelial cell	12 studies	42% ± 15%	Explore
endothelial cell of vascular tree	12 studies	36% ± 13%	Explore
type I pneumocyte	11 studies	38% ± 14%	Explore
secretory cell	11 studies	36% ± 17%	Explore
myeloid cell	11 studies	29% ± 13%	Explore
mesothelial cell	9 studies	25% ± 11%	Explore
plasmacytoid dendritic cell	9 studies	24% ± 5%	Explore
club cell	8 studies	35% ± 16%	Explore
platelet	8 studies	24% ± 9%	Explore
abnormal cell	8 studies	33% ± 14%	Explore
microglial cell	8 studies	28% ± 8%	Explore
respiratory goblet cell	7 studies	42% ± 15%	Explore
alveolar macrophage	6 studies	23% ± 6%	Explore
ionocyte	6 studies	34% ± 14%	Explore
megakaryocyte	6 studies	55% ± 22%	Explore
enterocyte	6 studies	28% ± 5%	Explore
goblet cell	6 studies	29% ± 11%	Explore
hematopoietic stem cell	6 studies	27% ± 8%	Explore
neuron	6 studies	37% ± 13%	Explore
oligodendrocyte precursor cell	6 studies	27% ± 8%	Explore
mast cell	6 studies	20% ± 6%	Explore
type II pneumocyte	5 studies	29% ± 8%	Explore
hematopoietic precursor cell	5 studies	27% ± 6%	Explore
mononuclear phagocyte	5 studies	23% ± 10%	Explore
progenitor cell	5 studies	22% ± 7%	Explore
squamous epithelial cell	4 studies	51% ± 23%	Explore
GABAergic neuron	4 studies	24% ± 8%	Explore
T cell	4 studies	23% ± 4%	Explore
glomerular endothelial cell	4 studies	47% ± 6%	Explore
kidney distal convoluted tubule epithelial cell	4 studies	38% ± 5%	Explore
epithelial cell of proximal tubule	4 studies	30% ± 13%	Explore
kidney loop of Henle epithelial cell	4 studies	39% ± 14%	Explore
brush cell	4 studies	26% ± 9%	Explore
luminal hormone-sensing cell of mammary gland	4 studies	24% ± 4%	Explore
enteroendocrine cell	4 studies	31% ± 12%	Explore
duct epithelial cell	3 studies	35% ± 12%	Explore
renal alpha-intercalated cell	3 studies	26% ± 6%	Explore
neural crest cell	3 studies	22% ± 4%	Explore
glial cell	3 studies	30% ± 13%	Explore
placental villous trophoblast	3 studies	58% ± 19%	Explore
CD16-positive, CD56-dim natural killer cell, human	3 studies	16% ± 0%	Explore
mucus secreting cell	3 studies	21% ± 3%	Explore
tissue-resident macrophage	3 studies	24% ± 4%	Explore
lymphocyte	3 studies	32% ± 10%	Explore
Mueller cell	3 studies	23% ± 6%	Explore
intermediate monocyte	3 studies	38% ± 11%	Explore
myoepithelial cell	3 studies	29% ± 7%	Explore
muscle cell	3 studies	27% ± 13%	Explore
glutamatergic neuron	3 studies	29% ± 8%	Explore
megakaryocyte-erythroid progenitor cell	3 studies	32% ± 19%	Explore
leukocyte	3 studies	20% ± 4%	Explore
melanocyte	3 studies	43% ± 15%	Explore
transit amplifying cell	3 studies	21% ± 5%	Explore
oligodendrocyte	3 studies	27% ± 3%	Explore

II. Expression across tissues

Name	Number of supported studies	Average coverage
lung	16 studies	31% ± 15%	Explore
brain	8 studies	27% ± 9%	Explore
intestine	8 studies	23% ± 8%	Explore
peripheral blood	7 studies	21% ± 5%	Explore
kidney	7 studies	25% ± 7%	Explore
uterus	4 studies	35% ± 17%	Explore
breast	4 studies	21% ± 3%	Explore
placenta	3 studies	40% ± 9%	Explore
eye	3 studies	24% ± 4%	Explore
bone marrow	3 studies	19% ± 5%	Explore
liver	3 studies	31% ± 10%	Explore

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
breast	100%	15346.78	459 / 459	100%	374.56	1118 / 1118
esophagus	100%	13022.82	1445 / 1445	100%	179.47	183 / 183
prostate	100%	14249.57	245 / 245	100%	281.15	502 / 502
skin	100%	13251.77	1809 / 1809	100%	623.60	472 / 472
lung	100%	20653.71	578 / 578	100%	307.30	1154 / 1155
uterus	100%	16287.38	170 / 170	100%	265.38	458 / 459
ovary	100%	13406.31	180 / 180	100%	289.18	429 / 430
thymus	100%	15559.87	653 / 653	100%	368.45	603 / 605
kidney	100%	16031.15	89 / 89	100%	514.05	898 / 901
stomach	100%	15439.36	359 / 359	100%	229.56	285 / 286
intestine	100%	15892.23	966 / 966	99%	260.43	524 / 527
brain	99%	7843.15	2623 / 2642	100%	500.85	704 / 705
bladder	100%	16096.19	21 / 21	99%	273.02	499 / 504
adrenal gland	100%	16245.85	258 / 258	98%	210.23	226 / 230
pancreas	99%	5824.55	324 / 328	99%	427.20	176 / 178
liver	100%	8339.60	226 / 226	96%	162.51	390 / 406
adipose	100%	15813.21	1204 / 1204	0%	0	0 / 0
blood vessel	100%	25572.71	1335 / 1335	0%	0	0 / 0
eye	0%	0	0 / 0	100%	667.62	80 / 80
lymph node	0%	0	0 / 0	100%	129.35	29 / 29
spleen	100%	12006.03	241 / 241	0%	0	0 / 0
tonsil	0%	0	0 / 0	100%	190.07	45 / 45
ureter	0%	0	0 / 0	100%	110.38	1 / 1
heart	100%	12625.41	857 / 861	0%	0	0 / 0
peripheral blood	94%	7971.71	876 / 929	0%	0	0 / 0
muscle	93%	5153.86	748 / 803	0%	0	0 / 0
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
gingiva	0%	0	0 / 0	0%	0	0 / 0
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0

III. Associated gene sets

GO_0031398	Biological process	positive regulation of protein ubiquitination
GO_0043518	Biological process	negative regulation of DNA damage response, signal transduction by p53 class mediator
GO_0006606	Biological process	protein import into nucleus
GO_1902254	Biological process	negative regulation of intrinsic apoptotic signaling pathway by p53 class mediator
GO_0070062	Cellular component	extracellular exosome
GO_0005654	Cellular component	nucleoplasm
GO_0016020	Cellular component	membrane
GO_0005737	Cellular component	cytoplasm
GO_0005634	Cellular component	nucleus
GO_0005515	Molecular function	protein binding
GO_0003674	Molecular function	molecular_function
GO_0002039	Molecular function	p53 binding

IV. Literature review

[source]

Gene name	PTTG1IP
Protein name	Pituitary tumor-transforming gene 1 protein-interacting protein (Pituitary tumor-transforming gene protein-binding factor) (PBF) (PTTG-binding factor) PTTG1 interacting protein PTTG1 interacting protein (cDNA FLJ58034, moderately similar to Pituitary tumor-transforming gene 1protein-interacting protein)
Synonyms	C21orf3 C21orf1
Description	FUNCTION: May facilitate PTTG1 nuclear translocation.
Accessions	ENST00000330938.8 ENST00000397887.7 A8MZH8 B4DPZ0 A8MXQ1 ENST00000445724.3 ENST00000397886.3 P53801

PTTG1IP report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

IV. Literature review