PTGER2 report

II. Expression across tissues

III. Associated gene sets

GO_0009624Biological processresponse to nematode
GO_0071380Biological processcellular response to prostaglandin E stimulus
GO_0007186Biological processG protein-coupled receptor signaling pathway
GO_0007204Biological processpositive regulation of cytosolic calcium ion concentration
GO_0006954Biological processinflammatory response
GO_0032570Biological processresponse to progesterone
GO_0042127Biological processregulation of cell population proliferation
GO_0032496Biological processresponse to lipopolysaccharide
GO_0007189Biological processadenylate cyclase-activating G protein-coupled receptor signaling pathway
GO_0005886Cellular componentplasma membrane
GO_0004957Molecular functionprostaglandin E receptor activity

IV. Literature review

[source]
Gene namePTGER2
Protein nameProstaglandin E receptor 2
Prostaglandin E2 receptor EP2 subtype (PGE receptor EP2 subtype) (PGE2 receptor EP2 subtype) (Prostanoid EP2 receptor)
Synonyms
DescriptionFUNCTION: Receptor for prostaglandin E2 (PGE2). The activity of this receptor is mediated by G(s) proteins that stimulate adenylate cyclase. The subsequent raise in intracellular cAMP is responsible for the relaxing effect of this receptor on smooth muscle.

AccessionsENST00000557436.1
ENST00000245457.6
P43116
G3V2Y6