PTDSS1 | OmnibusX

I. Expression across cell types

Name	Number of supported studies	Average coverage
CD4-positive, alpha-beta T cell	13 studies	20% ± 6%	Explore
memory B cell	12 studies	19% ± 2%	Explore
regulatory T cell	12 studies	21% ± 4%	Explore
naive B cell	11 studies	21% ± 3%	Explore
CD8-positive, alpha-beta T cell	11 studies	22% ± 7%	Explore
B cell	10 studies	21% ± 3%	Explore
natural killer cell	10 studies	19% ± 3%	Explore
CD4-positive, alpha-beta memory T cell	8 studies	23% ± 5%	Explore
mucosal invariant T cell	7 studies	19% ± 2%	Explore
naive thymus-derived CD8-positive, alpha-beta T cell	7 studies	21% ± 6%	Explore
hematopoietic precursor cell	6 studies	25% ± 6%	Explore
T cell	6 studies	19% ± 4%	Explore
gamma-delta T cell	6 studies	22% ± 11%	Explore
classical monocyte	5 studies	25% ± 5%	Explore
conventional dendritic cell	5 studies	29% ± 12%	Explore
endothelial cell	5 studies	23% ± 7%	Explore
CD16-negative, CD56-bright natural killer cell, human	5 studies	22% ± 3%	Explore
naive thymus-derived CD4-positive, alpha-beta T cell	5 studies	20% ± 4%	Explore
plasmacytoid dendritic cell	5 studies	23% ± 6%	Explore
CD8-positive, alpha-beta memory T cell	5 studies	24% ± 7%	Explore
dendritic cell	4 studies	32% ± 13%	Explore
hematopoietic stem cell	4 studies	24% ± 3%	Explore
precursor B cell	4 studies	22% ± 4%	Explore
CD16-positive, CD56-dim natural killer cell, human	4 studies	20% ± 2%	Explore
epithelial cell	4 studies	27% ± 11%	Explore
T follicular helper cell	4 studies	18% ± 1%	Explore
macrophage	4 studies	18% ± 1%	Explore
glutamatergic neuron	4 studies	43% ± 17%	Explore
effector memory CD4-positive, alpha-beta T cell	4 studies	22% ± 5%	Explore
abnormal cell	4 studies	18% ± 4%	Explore
non-classical monocyte	3 studies	26% ± 8%	Explore
neuron	3 studies	21% ± 3%	Explore
myeloid cell	3 studies	26% ± 9%	Explore
immature B cell	3 studies	22% ± 4%	Explore
pro-B cell	3 studies	22% ± 4%	Explore
cardiac muscle cell	3 studies	21% ± 2%	Explore
effector CD4-positive, alpha-beta T cell	3 studies	31% ± 6%	Explore
GABAergic neuron	3 studies	44% ± 8%	Explore
group 3 innate lymphoid cell	3 studies	21% ± 5%	Explore
transit amplifying cell	3 studies	25% ± 4%	Explore
mature NK T cell	3 studies	17% ± 1%	Explore
effector memory CD8-positive, alpha-beta T cell	3 studies	17% ± 1%	Explore

II. Expression across tissues

Name	Number of supported studies	Average coverage
peripheral blood	8 studies	19% ± 2%	Explore
brain	4 studies	32% ± 11%	Explore
lymph node	3 studies	17% ± 3%	Explore
liver	3 studies	21% ± 5%	Explore

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
ovary	100%	3412.43	180 / 180	100%	52.44	430 / 430
stomach	100%	2437.50	359 / 359	100%	59.25	286 / 286
esophagus	100%	2693.95	1444 / 1445	100%	58.54	183 / 183
lung	100%	3329.31	577 / 578	100%	76.44	1155 / 1155
skin	100%	4897.72	1809 / 1809	100%	82.08	471 / 472
uterus	100%	3015.31	170 / 170	100%	55.24	458 / 459
breast	100%	2923.55	459 / 459	100%	61.05	1115 / 1118
intestine	100%	2988.79	966 / 966	100%	61.92	525 / 527
bladder	100%	3186.76	21 / 21	100%	62.10	502 / 504
prostate	100%	2490.29	245 / 245	99%	42.95	499 / 502
thymus	100%	3125.61	653 / 653	99%	45.41	601 / 605
brain	99%	2990.12	2620 / 2642	100%	45.01	704 / 705
pancreas	99%	2446.45	326 / 328	99%	39.90	177 / 178
liver	100%	2530.26	226 / 226	99%	38.26	400 / 406
kidney	100%	2422.92	89 / 89	98%	34.02	881 / 901
adrenal gland	100%	2874.46	258 / 258	91%	22.94	210 / 230
adipose	100%	3001.96	1204 / 1204	0%	0	0 / 0
eye	0%	0	0 / 0	100%	91.51	80 / 80
lymph node	0%	0	0 / 0	100%	69.42	29 / 29
muscle	100%	2324.81	803 / 803	0%	0	0 / 0
spleen	100%	3934.12	241 / 241	0%	0	0 / 0
tonsil	0%	0	0 / 0	100%	56.91	45 / 45
ureter	0%	0	0 / 0	100%	40.92	1 / 1
blood vessel	100%	3025.36	1334 / 1335	0%	0	0 / 0
heart	98%	7043.54	846 / 861	0%	0	0 / 0
peripheral blood	98%	4392.95	912 / 929	0%	0	0 / 0
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
gingiva	0%	0	0 / 0	0%	0	0 / 0
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0

III. Associated gene sets

GO_0006659	Biological process	phosphatidylserine biosynthetic process
GO_0016020	Cellular component	membrane
GO_0005789	Cellular component	endoplasmic reticulum membrane
GO_0016740	Molecular function	transferase activity
GO_0106245	Molecular function	L-serine-phosphatidylethanolamine phosphatidyltransferase activity
GO_0106258	Molecular function	L-serine-phosphatidylcholine phosphatidyltransferase activity

IV. Literature review

[source]

Gene name	PTDSS1
Protein name	Phosphatidylserine synthase (EC 2.7.8.29) (Serine-exchange enzyme) Phosphatidylserine synthase 1 Phosphatidylserine synthase 1 (PSS-1) (PtdSer synthase 1) (EC 2.7.8.29) (Serine-exchange enzyme I)
Synonyms	KIAA0024 PSSA hCG_15747
Description	FUNCTION: Catalyzes a base-exchange reaction in which the polar head group of phosphatidylethanolamine (PE) or phosphatidylcholine (PC) is replaced by L-serine . Catalyzes mainly the conversion of phosphatidylcholine . Also converts, in vitro and to a lesser extent, phosphatidylethanolamine . . FUNCTION: Catalyzes a base-exchange reaction in which the polar head group of phosphatidylethanolamine (PE) is replaced by L-serine. .
Accessions	P48651 ENST00000517309.6 [P48651-1] J3KNR6 Q9BSY0 ENST00000337004.8 ENST00000522072.1 [P48651-3]

PTDSS1 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

IV. Literature review