PTBP2 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_2000177Biological processregulation of neural precursor cell proliferation
GO_0043484Biological processregulation of RNA splicing
GO_0033119Biological processnegative regulation of RNA splicing
GO_0006376Biological processmRNA splice site recognition
GO_0005681Cellular componentspliceosomal complex
GO_0005634Cellular componentnucleus
GO_0003729Molecular functionmRNA binding
GO_0003723Molecular functionRNA binding

IV. Literature review

[source]
Gene namePTBP2
Protein namePolypyrimidine tract binding protein 2 (cDNA FLJ55578, highly similar to Polypyrimidine tract-binding protein 2)
Polypyrimidine tract binding protein 2
Polypyrimidine tract-binding protein 2 (Neural polypyrimidine tract-binding protein) (Neurally-enriched homolog of PTB) (PTB-like protein)
PTBP2
SynonymsNPTB
PTB
PTBLP
DescriptionFUNCTION: RNA-binding protein which binds to intronic polypyrimidine tracts and mediates negative regulation of exons splicing. May antagonize in a tissue-specific manner the ability of NOVA1 to activate exon selection. In addition to its function in pre-mRNA splicing, plays also a role in the regulation of translation. .; FUNCTION: [Isoform 5]: Reduced affinity for RNA. .

AccessionsA0A7I2RVZ4
Q9UKA9
A0A6Q8PEZ3
A0A6Q8PH43
ENST00000675365.1
ENST00000674951.1 [Q9UKA9-1]
A0A6Q8PFE6
ENST00000476419.5 [Q9UKA9-5]
ENST00000676292.1
ENST00000609116.5 [Q9UKA9-2]
A0A6Q8PFT8
A0A6Q8PH82
A0A6Q8PFC0
ENST00000370198.5 [Q9UKA9-4]
ENST00000674579.1
ENST00000676096.1
ENST00000675401.1
ENST00000482253.5
ENST00000675735.1
B4DI28
ENST00000370197.5 [Q9UKA9-3]
O95652
ENST00000426398.3