Name | Number of supported studies | Average coverage | |
---|---|---|---|
endothelial cell | 24 studies | 35% ± 15% | |
astrocyte | 19 studies | 39% ± 16% | |
oligodendrocyte | 15 studies | 66% ± 16% | |
oligodendrocyte precursor cell | 14 studies | 47% ± 17% | |
glutamatergic neuron | 12 studies | 50% ± 24% | |
microglial cell | 12 studies | 35% ± 10% | |
GABAergic neuron | 11 studies | 49% ± 21% | |
pericyte | 11 studies | 37% ± 17% | |
fibroblast | 10 studies | 37% ± 14% | |
smooth muscle cell | 10 studies | 32% ± 10% | |
adipocyte | 9 studies | 39% ± 11% | |
neuron | 8 studies | 48% ± 24% | |
epithelial cell | 8 studies | 29% ± 12% | |
macrophage | 8 studies | 36% ± 14% | |
interneuron | 6 studies | 61% ± 11% | |
mast cell | 6 studies | 24% ± 6% | |
Mueller cell | 6 studies | 41% ± 23% | |
endothelial cell of lymphatic vessel | 6 studies | 46% ± 15% | |
amacrine cell | 5 studies | 36% ± 18% | |
retina horizontal cell | 5 studies | 35% ± 21% | |
cardiac muscle cell | 5 studies | 25% ± 4% | |
dendritic cell | 5 studies | 21% ± 3% | |
myeloid cell | 5 studies | 21% ± 6% | |
monocyte | 5 studies | 28% ± 6% | |
type I pneumocyte | 5 studies | 29% ± 10% | |
type II pneumocyte | 5 studies | 23% ± 7% | |
glial cell | 4 studies | 35% ± 8% | |
granule cell | 4 studies | 44% ± 8% | |
retinal bipolar neuron | 4 studies | 33% ± 26% | |
B cell | 4 studies | 26% ± 9% | |
mesothelial cell | 4 studies | 25% ± 7% | |
retinal rod cell | 4 studies | 28% ± 17% | |
club cell | 4 studies | 31% ± 10% | |
differentiation-committed oligodendrocyte precursor | 3 studies | 51% ± 9% | |
GABAergic interneuron | 3 studies | 43% ± 6% | |
progenitor cell | 3 studies | 47% ± 9% | |
retinal cone cell | 3 studies | 31% ± 16% | |
CD4-positive, alpha-beta T cell | 3 studies | 19% ± 0% | |
vein endothelial cell | 3 studies | 40% ± 25% | |
GABAergic amacrine cell | 3 studies | 47% ± 19% | |
glycinergic amacrine cell | 3 studies | 40% ± 20% | |
rod bipolar cell | 3 studies | 31% ± 13% | |
endothelial cell of vascular tree | 3 studies | 40% ± 23% | |
hepatocyte | 3 studies | 38% ± 13% | |
abnormal cell | 3 studies | 31% ± 21% | |
ependymal cell | 3 studies | 47% ± 17% | |
myofibroblast cell | 3 studies | 40% ± 15% | |
T cell | 3 studies | 26% ± 4% | |
alveolar macrophage | 3 studies | 35% ± 8% | |
capillary endothelial cell | 3 studies | 24% ± 6% | |
natural killer cell | 3 studies | 22% ± 3% | |
respiratory goblet cell | 3 studies | 30% ± 13% | |
lymphocyte | 3 studies | 32% ± 15% | |
muscle cell | 3 studies | 39% ± 31% | |
basal cell | 3 studies | 40% ± 20% | |
transit amplifying cell | 3 studies | 38% ± 28% | |
mucus secreting cell | 3 studies | 27% ± 9% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
brain | 100% | 2472.12 | 2637 / 2642 | 100% | 9.25 | 705 / 705 |
ovary | 100% | 2170.23 | 180 / 180 | 99% | 7.43 | 427 / 430 |
prostate | 100% | 2217.67 | 244 / 245 | 99% | 4.18 | 499 / 502 |
breast | 100% | 2613.80 | 459 / 459 | 99% | 4.58 | 1105 / 1118 |
esophagus | 100% | 2921.80 | 1442 / 1445 | 99% | 4.17 | 181 / 183 |
lung | 100% | 1704.65 | 577 / 578 | 99% | 3.97 | 1141 / 1155 |
uterus | 100% | 3432.62 | 170 / 170 | 98% | 5.70 | 452 / 459 |
thymus | 100% | 2260.67 | 652 / 653 | 98% | 5.22 | 594 / 605 |
kidney | 100% | 1217.71 | 89 / 89 | 96% | 4.30 | 862 / 901 |
bladder | 100% | 3016.33 | 21 / 21 | 94% | 3.34 | 475 / 504 |
stomach | 100% | 1841.66 | 358 / 359 | 93% | 2.91 | 266 / 286 |
skin | 100% | 1438.33 | 1805 / 1809 | 90% | 3.56 | 426 / 472 |
adrenal gland | 100% | 1327.37 | 258 / 258 | 90% | 2.22 | 206 / 230 |
intestine | 100% | 3951.31 | 966 / 966 | 89% | 2.25 | 469 / 527 |
pancreas | 90% | 688.74 | 295 / 328 | 98% | 3.87 | 174 / 178 |
liver | 90% | 641.28 | 203 / 226 | 77% | 2.03 | 312 / 406 |
adipose | 100% | 2419.03 | 1204 / 1204 | 0% | 0 | 0 / 0 |
blood vessel | 100% | 2430.00 | 1335 / 1335 | 0% | 0 | 0 / 0 |
spleen | 100% | 2129.95 | 241 / 241 | 0% | 0 | 0 / 0 |
ureter | 0% | 0 | 0 / 0 | 100% | 1.64 | 1 / 1 |
muscle | 99% | 1165.05 | 796 / 803 | 0% | 0 | 0 / 0 |
heart | 93% | 864.71 | 803 / 861 | 0% | 0 | 0 / 0 |
tonsil | 0% | 0 | 0 / 0 | 89% | 2.82 | 40 / 45 |
lymph node | 0% | 0 | 0 / 0 | 86% | 2.41 | 25 / 29 |
peripheral blood | 59% | 592.59 | 549 / 929 | 0% | 0 | 0 / 0 |
eye | 0% | 0 | 0 / 0 | 55% | 1.61 | 44 / 80 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
GO_2000177 | Biological process | regulation of neural precursor cell proliferation |
GO_0043484 | Biological process | regulation of RNA splicing |
GO_0033119 | Biological process | negative regulation of RNA splicing |
GO_0006376 | Biological process | mRNA splice site recognition |
GO_0005681 | Cellular component | spliceosomal complex |
GO_0005634 | Cellular component | nucleus |
GO_0003729 | Molecular function | mRNA binding |
GO_0003723 | Molecular function | RNA binding |
Gene name | PTBP2 |
Protein name | Polypyrimidine tract binding protein 2 (cDNA FLJ55578, highly similar to Polypyrimidine tract-binding protein 2) Polypyrimidine tract binding protein 2 Polypyrimidine tract-binding protein 2 (Neural polypyrimidine tract-binding protein) (Neurally-enriched homolog of PTB) (PTB-like protein) PTBP2 |
Synonyms | NPTB PTB PTBLP |
Description | FUNCTION: RNA-binding protein which binds to intronic polypyrimidine tracts and mediates negative regulation of exons splicing. May antagonize in a tissue-specific manner the ability of NOVA1 to activate exon selection. In addition to its function in pre-mRNA splicing, plays also a role in the regulation of translation. .; FUNCTION: [Isoform 5]: Reduced affinity for RNA. . |
Accessions | A0A7I2RVZ4 Q9UKA9 A0A6Q8PEZ3 A0A6Q8PH43 ENST00000675365.1 ENST00000674951.1 [Q9UKA9-1] A0A6Q8PFE6 ENST00000476419.5 [Q9UKA9-5] ENST00000676292.1 ENST00000609116.5 [Q9UKA9-2] A0A6Q8PFT8 A0A6Q8PH82 A0A6Q8PFC0 ENST00000370198.5 [Q9UKA9-4] ENST00000674579.1 ENST00000676096.1 ENST00000675401.1 ENST00000482253.5 ENST00000675735.1 B4DI28 ENST00000370197.5 [Q9UKA9-3] O95652 ENST00000426398.3 |