PSMD12 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_0043161Biological processproteasome-mediated ubiquitin-dependent protein catabolic process
GO_0000502Cellular componentproteasome complex
GO_0034774Cellular componentsecretory granule lumen
GO_1904813Cellular componentficolin-1-rich granule lumen
GO_0070062Cellular componentextracellular exosome
GO_0005654Cellular componentnucleoplasm
GO_0005829Cellular componentcytosol
GO_0005576Cellular componentextracellular region
GO_0005838Cellular componentproteasome regulatory particle
GO_0008541Cellular componentproteasome regulatory particle, lid subcomplex
GO_0022624Cellular componentproteasome accessory complex
GO_0016020Cellular componentmembrane
GO_0005737Cellular componentcytoplasm
GO_0005515Molecular functionprotein binding

IV. Literature review

[source]
Gene namePSMD12
Protein nameProteasome (Prosome, macropain) 26S subunit, non-ATPase, 12, isoform CRA_a (Proteasome 26S subunit non-ATPase 12 isoform 1)
Proteasome 26S subunit non-ATPase 12 isoform 2
Proteasome 26S subunit, non-ATPase 12
26S proteasome non-ATPase regulatory subunit 12 (26S proteasome regulatory subunit RPN5) (26S proteasome regulatory subunit p55)
SynonymshCG_1749256
DescriptionFUNCTION: Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair. .

AccessionsENST00000579365.5
J3KTJ5
ENST00000357146.4 [O00232-2]
O00232
J3KSK1
ENST00000356126.8 [O00232-1]
ENST00000584008.5
A0A0S2Z476
A0A0S2Z489