Name | Number of supported studies | Average coverage | |
---|---|---|---|
CD4-positive, alpha-beta T cell | 7 studies | 19% ± 3% | |
regulatory T cell | 7 studies | 18% ± 2% | |
naive B cell | 6 studies | 17% ± 1% | |
CD8-positive, alpha-beta T cell | 6 studies | 19% ± 1% | |
natural killer cell | 6 studies | 20% ± 4% | |
B cell | 5 studies | 19% ± 3% | |
CD8-positive, alpha-beta memory T cell | 5 studies | 17% ± 2% | |
memory B cell | 5 studies | 16% ± 1% | |
effector memory CD8-positive, alpha-beta T cell | 4 studies | 18% ± 1% | |
erythroblast | 4 studies | 25% ± 12% | |
gamma-delta T cell | 4 studies | 22% ± 8% | |
pancreatic A cell | 3 studies | 29% ± 9% | |
naive thymus-derived CD8-positive, alpha-beta T cell | 3 studies | 18% ± 2% | |
epithelial cell | 3 studies | 22% ± 4% | |
CD16-negative, CD56-bright natural killer cell, human | 3 studies | 17% ± 2% | |
CD16-positive, CD56-dim natural killer cell, human | 3 studies | 17% ± 1% | |
naive thymus-derived CD4-positive, alpha-beta T cell | 3 studies | 18% ± 1% | |
ciliated cell | 3 studies | 27% ± 6% | |
GABAergic neuron | 3 studies | 22% ± 6% | |
T follicular helper cell | 3 studies | 17% ± 1% |
Name | Number of supported studies | Average coverage | |
---|---|---|---|
pancreas | 3 studies | 25% ± 7% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
stomach | 100% | 1172.91 | 359 / 359 | 100% | 34.79 | 285 / 286 |
brain | 100% | 2269.45 | 2631 / 2642 | 100% | 82.55 | 705 / 705 |
lung | 100% | 2037.71 | 577 / 578 | 100% | 45.16 | 1152 / 1155 |
uterus | 100% | 2074.62 | 170 / 170 | 100% | 49.15 | 457 / 459 |
pancreas | 100% | 924.85 | 328 / 328 | 99% | 33.11 | 177 / 178 |
skin | 100% | 1816.73 | 1807 / 1809 | 99% | 50.60 | 469 / 472 |
thymus | 100% | 2556.65 | 653 / 653 | 99% | 43.08 | 600 / 605 |
liver | 100% | 1775.55 | 226 / 226 | 99% | 35.26 | 402 / 406 |
prostate | 100% | 1496.41 | 244 / 245 | 99% | 50.12 | 499 / 502 |
intestine | 100% | 1582.48 | 963 / 966 | 99% | 35.99 | 523 / 527 |
ovary | 100% | 2069.88 | 180 / 180 | 99% | 25.25 | 425 / 430 |
esophagus | 100% | 1391.30 | 1439 / 1445 | 99% | 31.54 | 181 / 183 |
breast | 100% | 1787.29 | 459 / 459 | 98% | 44.41 | 1098 / 1118 |
bladder | 100% | 1880.57 | 21 / 21 | 97% | 37.76 | 491 / 504 |
adrenal gland | 100% | 2225.44 | 258 / 258 | 97% | 49.39 | 223 / 230 |
kidney | 100% | 1496.16 | 89 / 89 | 97% | 34.93 | 873 / 901 |
adipose | 100% | 1954.42 | 1204 / 1204 | 0% | 0 | 0 / 0 |
blood vessel | 100% | 2156.15 | 1335 / 1335 | 0% | 0 | 0 / 0 |
lymph node | 0% | 0 | 0 / 0 | 100% | 75.23 | 29 / 29 |
muscle | 100% | 2637.52 | 803 / 803 | 0% | 0 | 0 / 0 |
spleen | 100% | 2120.33 | 241 / 241 | 0% | 0 | 0 / 0 |
tonsil | 0% | 0 | 0 / 0 | 100% | 47.77 | 45 / 45 |
ureter | 0% | 0 | 0 / 0 | 100% | 18.89 | 1 / 1 |
eye | 0% | 0 | 0 / 0 | 98% | 27.72 | 78 / 80 |
heart | 96% | 1279.08 | 825 / 861 | 0% | 0 | 0 / 0 |
peripheral blood | 96% | 1867.64 | 888 / 929 | 0% | 0 | 0 / 0 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
GO_0034418 | Biological process | urate biosynthetic process |
GO_0006015 | Biological process | 5-phosphoribose 1-diphosphate biosynthetic process |
GO_0006164 | Biological process | purine nucleotide biosynthetic process |
GO_0006144 | Biological process | purine nucleobase metabolic process |
GO_0006221 | Biological process | pyrimidine nucleotide biosynthetic process |
GO_0009156 | Biological process | ribonucleoside monophosphate biosynthetic process |
GO_0007399 | Biological process | nervous system development |
GO_0046101 | Biological process | hypoxanthine biosynthetic process |
GO_0005829 | Cellular component | cytosol |
GO_0002189 | Cellular component | ribose phosphate diphosphokinase complex |
GO_0005737 | Cellular component | cytoplasm |
GO_0042803 | Molecular function | protein homodimerization activity |
GO_0004749 | Molecular function | ribose phosphate diphosphokinase activity |
GO_0005524 | Molecular function | ATP binding |
GO_0005515 | Molecular function | protein binding |
GO_0042802 | Molecular function | identical protein binding |
GO_0000287 | Molecular function | magnesium ion binding |
GO_0016301 | Molecular function | kinase activity |
Gene name | PRPS1 |
Protein name | Ribose-phosphate pyrophosphokinase 1 (EC 2.7.6.1) (PPRibP) (Phosphoribosyl pyrophosphate synthase I) (PRS-I) Ribose-phosphate pyrophosphokinase 1 (EC 2.7.6.1) (Phosphoribosyl pyrophosphate synthase I) ribose-phosphate diphosphokinase (EC 2.7.6.1) Ribose-phosphate pyrophosphokinase (EC 2.7.6.1) Phosphoribosyl pyrophosphate synthetase 1 |
Synonyms | |
Description | FUNCTION: Catalyzes the synthesis of phosphoribosylpyrophosphate (PRPP) that is essential for nucleotide synthesis. . FUNCTION: Catalyzes the synthesis of phosphoribosylpyrophosphate (PRPP) that is essential for nucleotide synthesis. . |
Accessions | ENST00000676092.1 A0A6Q8PGX9 B1ALA9 A0A6Q8PGP2 A0A6Q8PHI4 Q15244 A0A6Q8PFD7 B1ALA7 ENST00000674826.1 A0A0A0MRQ9 ENST00000372428.9 ENST00000674843.1 A0A6Q8PHK9 ENST00000644642.1 A0A6Q8PFD1 ENST00000675875.1 ENST00000676365.1 ENST00000675630.1 ENST00000646815.1 A0A6Q8PG31 ENST00000643795.2 ENST00000675720.1 A0A6Q8PG82 P60891 ENST00000675124.1 A0A6Q8PGF9 A0A2R8Y7H4 ENST00000675263.1 ENST00000675353.1 ENST00000372418.4 ENST00000372419.3 ENST00000675046.1 A0A6Q8PG33 A0A6Q8PG13 ENST00000645638.1 ENST00000675921.1 ENST00000372435.10 [P60891-1] ENST00000675082.1 A0A6Q8PEU0 ENST00000676322.1 |