PRPS1 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_0034418Biological processurate biosynthetic process
GO_0006015Biological process5-phosphoribose 1-diphosphate biosynthetic process
GO_0006164Biological processpurine nucleotide biosynthetic process
GO_0006144Biological processpurine nucleobase metabolic process
GO_0006221Biological processpyrimidine nucleotide biosynthetic process
GO_0009156Biological processribonucleoside monophosphate biosynthetic process
GO_0007399Biological processnervous system development
GO_0046101Biological processhypoxanthine biosynthetic process
GO_0005829Cellular componentcytosol
GO_0002189Cellular componentribose phosphate diphosphokinase complex
GO_0005737Cellular componentcytoplasm
GO_0042803Molecular functionprotein homodimerization activity
GO_0004749Molecular functionribose phosphate diphosphokinase activity
GO_0005524Molecular functionATP binding
GO_0005515Molecular functionprotein binding
GO_0042802Molecular functionidentical protein binding
GO_0000287Molecular functionmagnesium ion binding
GO_0016301Molecular functionkinase activity

IV. Literature review

[source]
Gene namePRPS1
Protein nameRibose-phosphate pyrophosphokinase 1 (EC 2.7.6.1) (PPRibP) (Phosphoribosyl pyrophosphate synthase I) (PRS-I)
Ribose-phosphate pyrophosphokinase 1 (EC 2.7.6.1) (Phosphoribosyl pyrophosphate synthase I)
ribose-phosphate diphosphokinase (EC 2.7.6.1)
Ribose-phosphate pyrophosphokinase (EC 2.7.6.1)
Phosphoribosyl pyrophosphate synthetase 1
Synonyms
DescriptionFUNCTION: Catalyzes the synthesis of phosphoribosylpyrophosphate (PRPP) that is essential for nucleotide synthesis. .

FUNCTION: Catalyzes the synthesis of phosphoribosylpyrophosphate (PRPP) that is essential for nucleotide synthesis. .

AccessionsENST00000676092.1
A0A6Q8PGX9
B1ALA9
A0A6Q8PGP2
A0A6Q8PHI4
Q15244
A0A6Q8PFD7
B1ALA7
ENST00000674826.1
A0A0A0MRQ9
ENST00000372428.9
ENST00000674843.1
A0A6Q8PHK9
ENST00000644642.1
A0A6Q8PFD1
ENST00000675875.1
ENST00000676365.1
ENST00000675630.1
ENST00000646815.1
A0A6Q8PG31
ENST00000643795.2
ENST00000675720.1
A0A6Q8PG82
P60891
ENST00000675124.1
A0A6Q8PGF9
A0A2R8Y7H4
ENST00000675263.1
ENST00000675353.1
ENST00000372418.4
ENST00000372419.3
ENST00000675046.1
A0A6Q8PG33
A0A6Q8PG13
ENST00000645638.1
ENST00000675921.1
ENST00000372435.10 [P60891-1]
ENST00000675082.1
A0A6Q8PEU0
ENST00000676322.1