PROP1 report

I. Expression across cell types

Insufficient scRNA-seq data for expression of PROP1 at single-cell level.

II. Expression across tissues

sc-RNAseq data

Insufficient scRNA-seq data for expression of PROP1 at tissue level.

III. Associated gene sets

GO_0006357Biological processregulation of transcription by RNA polymerase II
GO_0021979Biological processhypothalamus cell differentiation
GO_0000122Biological processnegative regulation of transcription by RNA polymerase II
GO_0009953Biological processdorsal/ventral pattern formation
GO_0043066Biological processnegative regulation of apoptotic process
GO_0001568Biological processblood vessel development
GO_0007417Biological processcentral nervous system development
GO_0006915Biological processapoptotic process
GO_0060126Biological processsomatotropin secreting cell differentiation
GO_0048850Biological processhypophysis morphogenesis
GO_0016477Biological processcell migration
GO_0045944Biological processpositive regulation of transcription by RNA polymerase II
GO_0000785Cellular componentchromatin
GO_0005667Cellular componenttranscription regulator complex
GO_0005634Cellular componentnucleus
GO_0000978Molecular functionRNA polymerase II cis-regulatory region sequence-specific DNA binding
GO_0001228Molecular functionDNA-binding transcription activator activity, RNA polymerase II-specific
GO_0001227Molecular functionDNA-binding transcription repressor activity, RNA polymerase II-specific
GO_0000981Molecular functionDNA-binding transcription factor activity, RNA polymerase II-specific
GO_0003682Molecular functionchromatin binding
GO_1990837Molecular functionsequence-specific double-stranded DNA binding
GO_0008013Molecular functionbeta-catenin binding
GO_0005515Molecular functionprotein binding

IV. Literature review

[source]
Gene namePROP1
Protein nameHomeobox protein prophet of Pit-1 (Pituitary-specific homeodomain factor)
Homeobox protein prophet of Pit-1 (PROP-1) (Pituitary-specific homeodomain factor)
SynonymshCG_40268
DescriptionFUNCTION: Possibly involved in the ontogenesis of pituitary gonadotropes, as well as somatotropes, lactotropes and caudomedial thyrotropes.

FUNCTION: Possibly involved in the ontogenesis of pituitary gonadotropes, as well as somatotropes, lactotropes and caudomedial thyrotropes. .

FUNCTION: Possibly involved in the ontogenesis of pituitary gonadotropes, as well as somatotropes, lactotropes and caudomedial thyrotropes. .

AccessionsA0A0G2JRP7
A0A0G2JQ02
ENST00000629850.1
O75360
ENST00000614006.2
ENST00000308304.2