Insufficient scRNA-seq data for expression of PROP1 at single-cell level.
Insufficient scRNA-seq data for expression of PROP1 at tissue level.
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| prostate | 50% | 2.00 | 123 / 245 | 0% | 0.00 | 1 / 502 |
| pancreas | 49% | 2.44 | 162 / 328 | 0% | 0 | 0 / 178 |
| brain | 39% | 2.78 | 1032 / 2642 | 0% | 0 | 0 / 705 |
| ovary | 37% | 1.44 | 66 / 180 | 0% | 0.01 | 1 / 430 |
| thymus | 27% | 0.92 | 174 / 653 | 0% | 0 | 0 / 605 |
| esophagus | 15% | 0.45 | 213 / 1445 | 1% | 0.01 | 1 / 183 |
| stomach | 11% | 0.26 | 41 / 359 | 1% | 0.01 | 2 / 286 |
| skin | 11% | 0.32 | 202 / 1809 | 0% | 0.00 | 1 / 472 |
| liver | 10% | 0.32 | 22 / 226 | 0% | 0 | 0 / 406 |
| breast | 8% | 0.20 | 38 / 459 | 1% | 0.01 | 6 / 1118 |
| spleen | 8% | 0.22 | 20 / 241 | 0% | 0 | 0 / 0 |
| uterus | 8% | 0.19 | 14 / 170 | 0% | 0 | 0 / 459 |
| muscle | 8% | 0.20 | 64 / 803 | 0% | 0 | 0 / 0 |
| intestine | 7% | 0.16 | 65 / 966 | 0% | 0.01 | 1 / 527 |
| kidney | 4% | 0.13 | 4 / 89 | 1% | 0.03 | 8 / 901 |
| peripheral blood | 5% | 0.14 | 49 / 929 | 0% | 0 | 0 / 0 |
| lung | 4% | 0.09 | 23 / 578 | 0% | 0.00 | 3 / 1155 |
| adipose | 4% | 0.10 | 49 / 1204 | 0% | 0 | 0 / 0 |
| blood vessel | 4% | 0.09 | 49 / 1335 | 0% | 0 | 0 / 0 |
| tonsil | 0% | 0 | 0 / 0 | 2% | 0.03 | 1 / 45 |
| adrenal gland | 2% | 0.03 | 4 / 258 | 0% | 0 | 0 / 230 |
| heart | 1% | 0.03 | 11 / 861 | 0% | 0 | 0 / 0 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bladder | 0% | 0 | 0 / 21 | 0% | 0 | 0 / 504 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| eye | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 80 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| lymph node | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 29 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
| GO_0006357 | Biological process | regulation of transcription by RNA polymerase II |
| GO_0021979 | Biological process | hypothalamus cell differentiation |
| GO_0000122 | Biological process | negative regulation of transcription by RNA polymerase II |
| GO_0009953 | Biological process | dorsal/ventral pattern formation |
| GO_0043066 | Biological process | negative regulation of apoptotic process |
| GO_0001568 | Biological process | blood vessel development |
| GO_0007417 | Biological process | central nervous system development |
| GO_0006915 | Biological process | apoptotic process |
| GO_0060126 | Biological process | somatotropin secreting cell differentiation |
| GO_0048850 | Biological process | hypophysis morphogenesis |
| GO_0016477 | Biological process | cell migration |
| GO_0045944 | Biological process | positive regulation of transcription by RNA polymerase II |
| GO_0000785 | Cellular component | chromatin |
| GO_0005667 | Cellular component | transcription regulator complex |
| GO_0005634 | Cellular component | nucleus |
| GO_0000978 | Molecular function | RNA polymerase II cis-regulatory region sequence-specific DNA binding |
| GO_0001228 | Molecular function | DNA-binding transcription activator activity, RNA polymerase II-specific |
| GO_0001227 | Molecular function | DNA-binding transcription repressor activity, RNA polymerase II-specific |
| GO_0000981 | Molecular function | DNA-binding transcription factor activity, RNA polymerase II-specific |
| GO_0003682 | Molecular function | chromatin binding |
| GO_1990837 | Molecular function | sequence-specific double-stranded DNA binding |
| GO_0008013 | Molecular function | beta-catenin binding |
| GO_0005515 | Molecular function | protein binding |
| Gene name | PROP1 |
| Protein name | Homeobox protein prophet of Pit-1 (Pituitary-specific homeodomain factor) Homeobox protein prophet of Pit-1 (PROP-1) (Pituitary-specific homeodomain factor) |
| Synonyms | hCG_40268 |
| Description | FUNCTION: Possibly involved in the ontogenesis of pituitary gonadotropes, as well as somatotropes, lactotropes and caudomedial thyrotropes. FUNCTION: Possibly involved in the ontogenesis of pituitary gonadotropes, as well as somatotropes, lactotropes and caudomedial thyrotropes. . FUNCTION: Possibly involved in the ontogenesis of pituitary gonadotropes, as well as somatotropes, lactotropes and caudomedial thyrotropes. . |
| Accessions | A0A0G2JRP7 A0A0G2JQ02 ENST00000629850.1 O75360 ENST00000614006.2 ENST00000308304.2 |