Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
esophagus | 100% | 3572.24 | 1445 / 1445 | 100% | 43.12 | 183 / 183 |
intestine | 100% | 3465.80 | 966 / 966 | 100% | 42.42 | 527 / 527 |
ovary | 100% | 2601.67 | 180 / 180 | 100% | 34.71 | 430 / 430 |
prostate | 100% | 2953.76 | 245 / 245 | 100% | 38.70 | 502 / 502 |
stomach | 100% | 2614.79 | 359 / 359 | 100% | 46.94 | 286 / 286 |
breast | 100% | 3131.08 | 459 / 459 | 100% | 43.73 | 1116 / 1118 |
lung | 100% | 2760.24 | 576 / 578 | 100% | 32.01 | 1154 / 1155 |
bladder | 100% | 3310.10 | 21 / 21 | 99% | 30.11 | 500 / 504 |
uterus | 100% | 2813.26 | 170 / 170 | 99% | 28.03 | 455 / 459 |
skin | 100% | 3696.98 | 1809 / 1809 | 98% | 37.72 | 464 / 472 |
liver | 100% | 2090.85 | 226 / 226 | 98% | 21.00 | 399 / 406 |
thymus | 100% | 2724.12 | 652 / 653 | 98% | 28.27 | 593 / 605 |
kidney | 100% | 2392.53 | 89 / 89 | 98% | 23.78 | 879 / 901 |
pancreas | 98% | 1687.51 | 322 / 328 | 98% | 22.73 | 175 / 178 |
brain | 96% | 1506.99 | 2543 / 2642 | 100% | 31.56 | 704 / 705 |
adrenal gland | 100% | 4330.39 | 258 / 258 | 95% | 21.52 | 219 / 230 |
adipose | 100% | 3372.30 | 1204 / 1204 | 0% | 0 | 0 / 0 |
blood vessel | 100% | 4046.48 | 1335 / 1335 | 0% | 0 | 0 / 0 |
lymph node | 0% | 0 | 0 / 0 | 100% | 18.28 | 29 / 29 |
muscle | 100% | 10418.66 | 803 / 803 | 0% | 0 | 0 / 0 |
spleen | 100% | 1940.43 | 241 / 241 | 0% | 0 | 0 / 0 |
ureter | 0% | 0 | 0 / 0 | 100% | 18.05 | 1 / 1 |
tonsil | 0% | 0 | 0 / 0 | 98% | 27.99 | 44 / 45 |
heart | 98% | 2689.33 | 840 / 861 | 0% | 0 | 0 / 0 |
eye | 0% | 0 | 0 / 0 | 84% | 12.33 | 67 / 80 |
peripheral blood | 83% | 1692.81 | 775 / 929 | 0% | 0 | 0 / 0 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
GO_0001932 | Biological process | regulation of protein phosphorylation |
GO_0141162 | Biological process | negative regulation of cAMP/PKA signal transduction |
GO_0035556 | Biological process | intracellular signal transduction |
GO_2000480 | Biological process | negative regulation of cAMP-dependent protein kinase activity |
GO_0005886 | Cellular component | plasma membrane |
GO_0016020 | Cellular component | membrane |
GO_0031588 | Cellular component | nucleotide-activated protein kinase complex |
GO_0005813 | Cellular component | centrosome |
GO_0070062 | Cellular component | extracellular exosome |
GO_0032991 | Cellular component | protein-containing complex |
GO_0005925 | Cellular component | focal adhesion |
GO_0005930 | Cellular component | axoneme |
GO_0044853 | Cellular component | plasma membrane raft |
GO_0005829 | Cellular component | cytosol |
GO_0005737 | Cellular component | cytoplasm |
GO_0097546 | Cellular component | ciliary base |
GO_0005952 | Cellular component | cAMP-dependent protein kinase complex |
GO_0030552 | Molecular function | cAMP binding |
GO_0004862 | Molecular function | cAMP-dependent protein kinase inhibitor activity |
GO_0019904 | Molecular function | protein domain specific binding |
GO_0008603 | Molecular function | cAMP-dependent protein kinase regulator activity |
GO_0031625 | Molecular function | ubiquitin protein ligase binding |
GO_0034236 | Molecular function | protein kinase A catalytic subunit binding |
GO_0005515 | Molecular function | protein binding |
Gene name | PRKAR2A |
Protein name | Protein kinase cAMP-dependent type II regulatory subunit alpha cAMP-dependent protein kinase type II-alpha regulatory subunit |
Synonyms | PKR2 PRKAR2 hCG_1779456 |
Description | FUNCTION: Regulatory subunit of the cAMP-dependent protein kinases involved in cAMP signaling in cells. Type II regulatory chains mediate membrane association by binding to anchoring proteins, including the MAP2 kinase. FUNCTION: Regulatory subunit of the cAMP-dependent protein kinases involved in cAMP signaling in cells. Type II regulatory chains mediate membrane association by binding to anchoring proteins, including the MAP2 kinase. . FUNCTION: Regulatory subunit of the cAMP-dependent protein kinases involved in cAMP signaling in cells. Type II regulatory chains mediate membrane association by binding to anchoring proteins, including the MAP2 kinase. . FUNCTION: Regulatory subunit of the cAMP-dependent protein kinases involved in cAMP signaling in cells. Type II regulatory chains mediate membrane association by binding to anchoring proteins, including the MAP2 kinase. . FUNCTION: Regulatory subunit of the cAMP-dependent protein kinases involved in cAMP signaling in cells. Type II regulatory chains mediate membrane association by binding to anchoring proteins, including the MAP2 kinase. . FUNCTION: Regulatory subunit of the cAMP-dependent protein kinases involved in cAMP signaling in cells. Type II regulatory chains mediate membrane association by binding to anchoring proteins, including the MAP2 kinase. . FUNCTION: Regulatory subunit of the cAMP-dependent protein kinases involved in cAMP signaling in cells. Type II regulatory chains mediate membrane association by binding to anchoring proteins, including the MAP2 kinase. . FUNCTION: Regulatory subunit of the cAMP-dependent protein kinases involved in cAMP signaling in cells. Type II regulatory chains mediate membrane association by binding to anchoring proteins, including the MAP2 kinase. . FUNCTION: Regulatory subunit of the cAMP-dependent protein kinases involved in cAMP signaling in cells. Type II regulatory chains mediate membrane association by binding to anchoring proteins, including the MAP2 kinase. . FUNCTION: Regulatory subunit of the cAMP-dependent protein kinases involved in cAMP signaling in cells. Type II regulatory chains mediate membrane association by binding to anchoring proteins, including the MAP2 kinase. . FUNCTION: Regulatory subunit of the cAMP-dependent protein kinases involved in cAMP signaling in cells. Type II regulatory chains mediate membrane association by binding to anchoring proteins, including the MAP2 kinase. . |
Accessions | A0A024R2W3 H7C330 H7C4A9 ENST00000265563.13 [P13861-1] ENST00000296446.12 [P13861-2] A0A9L9PY56 C9J830 ENST00000706570.1 P13861 A0A0S2Z472 ENST00000706572.1 A0A9L9PX32 ENST00000706575.1 ENST00000457914.5 ENST00000706577.1 ENST00000706573.1 ENST00000454963.5 [P13861-1] ENST00000706571.1 A0A9L9PXB4 ENST00000438535.1 A0A9L9PXB0 ENST00000437821.2 ENST00000419216.1 ENST00000706574.1 [P13861-1] A0A9L9PY59 ENST00000706576.1 A0A9L9PXM7 H7C1L0 A0A9L9PXP9 |