PREX1 report

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I. Expression across cell types

Cell ontologyData table

Name	Number of supported studies	Average coverage
macrophage	27 studies	29% ± 17%	Explore
natural killer cell	25 studies	23% ± 8%	Explore
endothelial cell	21 studies	28% ± 13%	Explore
classical monocyte	20 studies	25% ± 11%	Explore
astrocyte	16 studies	38% ± 17%	Explore
oligodendrocyte	16 studies	48% ± 17%	Explore
microglial cell	14 studies	55% ± 21%	Explore
monocyte	12 studies	28% ± 13%	Explore
CD16-positive, CD56-dim natural killer cell, human	12 studies	29% ± 11%	Explore
oligodendrocyte precursor cell	12 studies	34% ± 15%	Explore
T cell	10 studies	28% ± 13%	Explore
non-classical monocyte	10 studies	28% ± 11%	Explore
myeloid cell	10 studies	37% ± 16%	Explore
dendritic cell	10 studies	36% ± 16%	Explore
CD8-positive, alpha-beta T cell	9 studies	27% ± 8%	Explore
capillary endothelial cell	9 studies	29% ± 12%	Explore
B cell	8 studies	20% ± 2%	Explore
CD16-negative, CD56-bright natural killer cell, human	8 studies	26% ± 8%	Explore
conventional dendritic cell	8 studies	28% ± 15%	Explore
effector memory CD8-positive, alpha-beta T cell	8 studies	29% ± 9%	Explore
CD8-positive, alpha-beta memory T cell	7 studies	25% ± 7%	Explore
gamma-delta T cell	7 studies	21% ± 7%	Explore
regulatory T cell	7 studies	24% ± 9%	Explore
neutrophil	6 studies	25% ± 6%	Explore
leukocyte	6 studies	40% ± 17%	Explore
CD4-positive, alpha-beta T cell	6 studies	28% ± 7%	Explore
endothelial cell of artery	6 studies	21% ± 5%	Explore
plasmacytoid dendritic cell	6 studies	25% ± 9%	Explore
mature NK T cell	5 studies	28% ± 8%	Explore
mononuclear phagocyte	4 studies	31% ± 8%	Explore
mucosal invariant T cell	4 studies	25% ± 6%	Explore
lymphocyte	4 studies	47% ± 16%	Explore
innate lymphoid cell	4 studies	18% ± 3%	Explore
naive thymus-derived CD8-positive, alpha-beta T cell	3 studies	19% ± 4%	Explore
GABAergic neuron	3 studies	21% ± 3%	Explore
glomerular endothelial cell	3 studies	26% ± 2%	Explore
memory B cell	3 studies	19% ± 5%	Explore
glutamatergic neuron	3 studies	31% ± 6%	Explore
group 3 innate lymphoid cell	3 studies	35% ± 14%	Explore
CD4-positive, alpha-beta memory T cell	3 studies	19% ± 4%	Explore

II. Expression across tissues

sc-RNAseq dataData table

Name	Number of supported studies	Average coverage
brain	14 studies	30% ± 15%	Explore
peripheral blood	7 studies	23% ± 8%	Explore
lung	4 studies	19% ± 3%	Explore

Bulk RNAseq dataData table

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
brain	100%	10635.53	2634 / 2642	100%	127.85	702 / 705
breast	98%	6363.44	452 / 459	95%	112.33	1060 / 1118
thymus	100%	4479.32	650 / 653	90%	23.25	547 / 605
lung	100%	12764.99	578 / 578	73%	18.21	839 / 1155
kidney	81%	2331.38	72 / 89	77%	30.65	698 / 901
adrenal gland	98%	4284.37	254 / 258	60%	15.86	137 / 230
stomach	81%	2008.98	290 / 359	69%	16.22	196 / 286
prostate	88%	2466.25	216 / 245	53%	10.71	266 / 502
intestine	80%	2839.01	776 / 966	53%	11.99	278 / 527
skin	33%	708.26	605 / 1809	90%	52.45	424 / 472
bladder	62%	1700.38	13 / 21	52%	11.58	264 / 504
esophagus	57%	1324.71	817 / 1445	52%	11.08	95 / 183
peripheral blood	100%	32457.75	929 / 929	0%	0	0 / 0
spleen	100%	17918.31	241 / 241	0%	0	0 / 0
ureter	0%	0	0 / 0	100%	13.13	1 / 1
lymph node	0%	0	0 / 0	97%	59.42	28 / 29
adipose	96%	4179.70	1161 / 1204	0%	0	0 / 0
uterus	45%	992.22	76 / 170	51%	13.61	233 / 459
blood vessel	93%	5592.81	1245 / 1335	0%	0	0 / 0
ovary	18%	413.10	33 / 180	64%	15.21	275 / 430
pancreas	9%	195.48	29 / 328	70%	18.24	125 / 178
tonsil	0%	0	0 / 0	69%	18.68	31 / 45
heart	57%	1359.95	487 / 861	0%	0	0 / 0
liver	12%	257.29	26 / 226	37%	7.40	151 / 406
muscle	44%	1004.46	355 / 803	0%	0	0 / 0
eye	0%	0	0 / 0	33%	6.82	26 / 80
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
gingiva	0%	0	0 / 0	0%	0	0 / 0
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0