PPP2R5A | OmnibusX

I. Expression across cell types

Name	Number of supported studies	Average coverage
endothelial cell	25 studies	26% ± 7%	Explore
type I pneumocyte	10 studies	29% ± 9%	Explore
astrocyte	10 studies	34% ± 17%	Explore
oligodendrocyte	10 studies	32% ± 11%	Explore
natural killer cell	9 studies	22% ± 4%	Explore
adipocyte	9 studies	44% ± 16%	Explore
type II pneumocyte	8 studies	31% ± 10%	Explore
CD16-positive, CD56-dim natural killer cell, human	6 studies	23% ± 6%	Explore
CD8-positive, alpha-beta T cell	6 studies	19% ± 3%	Explore
epithelial cell	6 studies	30% ± 7%	Explore
vein endothelial cell	6 studies	33% ± 21%	Explore
endothelial cell of lymphatic vessel	5 studies	31% ± 13%	Explore
CD16-negative, CD56-bright natural killer cell, human	5 studies	18% ± 2%	Explore
effector memory CD8-positive, alpha-beta T cell	5 studies	19% ± 2%	Explore
myeloid cell	5 studies	20% ± 3%	Explore
cardiac muscle cell	5 studies	28% ± 7%	Explore
mast cell	5 studies	21% ± 4%	Explore
smooth muscle cell	5 studies	24% ± 4%	Explore
goblet cell	5 studies	23% ± 9%	Explore
CD4-positive, alpha-beta T cell	4 studies	17% ± 2%	Explore
mature NK T cell	4 studies	20% ± 4%	Explore
basal cell	4 studies	20% ± 5%	Explore
club cell	4 studies	19% ± 4%	Explore
capillary endothelial cell	4 studies	28% ± 12%	Explore
CD8-positive, alpha-beta memory T cell	4 studies	19% ± 2%	Explore
monocyte	4 studies	25% ± 2%	Explore
macrophage	4 studies	24% ± 3%	Explore
pericyte	4 studies	21% ± 8%	Explore
classical monocyte	3 studies	33% ± 4%	Explore
hematopoietic precursor cell	3 studies	20% ± 2%	Explore
non-classical monocyte	3 studies	29% ± 10%	Explore
microglial cell	3 studies	21% ± 4%	Explore
mucosal invariant T cell	3 studies	18% ± 2%	Explore
ciliated cell	3 studies	21% ± 5%	Explore
lymphocyte	3 studies	29% ± 12%	Explore
retina horizontal cell	3 studies	26% ± 8%	Explore
rod bipolar cell	3 studies	32% ± 10%	Explore
gamma-delta T cell	3 studies	22% ± 5%	Explore
endothelial cell of vascular tree	3 studies	28% ± 11%	Explore
hepatocyte	3 studies	36% ± 15%	Explore
GABAergic neuron	3 studies	24% ± 2%	Explore
glutamatergic neuron	3 studies	36% ± 4%	Explore
oligodendrocyte precursor cell	3 studies	27% ± 4%	Explore
T cell	3 studies	24% ± 2%	Explore
alveolar macrophage	3 studies	22% ± 8%	Explore
fibroblast	3 studies	17% ± 2%	Explore
renal alpha-intercalated cell	3 studies	35% ± 7%	Explore

II. Expression across tissues

Name	Number of supported studies	Average coverage
lung	5 studies	21% ± 6%	Explore
brain	5 studies	35% ± 12%	Explore
heart	4 studies	19% ± 3%	Explore
peripheral blood	3 studies	24% ± 1%	Explore
liver	3 studies	25% ± 8%	Explore
intestine	3 studies	17% ± 1%	Explore
adipose	3 studies	24% ± 3%	Explore

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
esophagus	100%	5376.26	1445 / 1445	100%	76.04	183 / 183
lung	100%	5981.65	578 / 578	100%	74.61	1155 / 1155
ovary	100%	1942.57	180 / 180	100%	51.00	430 / 430
pancreas	100%	3150.29	328 / 328	100%	55.87	178 / 178
stomach	100%	4565.90	359 / 359	100%	60.48	286 / 286
breast	100%	6074.10	459 / 459	100%	103.65	1117 / 1118
uterus	100%	3192.73	170 / 170	100%	57.39	458 / 459
liver	100%	3389.62	226 / 226	100%	78.79	405 / 406
kidney	100%	4084.28	89 / 89	100%	55.02	898 / 901
brain	100%	3011.42	2636 / 2642	100%	77.66	704 / 705
intestine	100%	3836.80	966 / 966	100%	62.50	525 / 527
prostate	100%	3183.33	245 / 245	99%	43.92	499 / 502
thymus	100%	4119.93	653 / 653	99%	67.78	601 / 605
bladder	100%	5345.24	21 / 21	99%	48.33	500 / 504
skin	100%	3909.78	1809 / 1809	96%	57.24	451 / 472
adrenal gland	99%	1661.31	256 / 258	90%	24.52	206 / 230
adipose	100%	6755.97	1204 / 1204	0%	0	0 / 0
blood vessel	100%	5117.56	1335 / 1335	0%	0	0 / 0
lymph node	0%	0	0 / 0	100%	46.96	29 / 29
muscle	100%	3208.31	803 / 803	0%	0	0 / 0
spleen	100%	5462.98	241 / 241	0%	0	0 / 0
tonsil	0%	0	0 / 0	100%	50.99	45 / 45
ureter	0%	0	0 / 0	100%	26.69	1 / 1
heart	99%	4078.90	849 / 861	0%	0	0 / 0
peripheral blood	98%	4724.10	909 / 929	0%	0	0 / 0
eye	0%	0	0 / 0	90%	43.05	72 / 80
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
gingiva	0%	0	0 / 0	0%	0	0 / 0
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0

III. Associated gene sets

GO_0006470	Biological process	protein dephosphorylation
GO_0007165	Biological process	signal transduction
GO_0090219	Biological process	negative regulation of lipid kinase activity
GO_0035307	Biological process	positive regulation of protein dephosphorylation
GO_1903077	Biological process	negative regulation of protein localization to plasma membrane
GO_0000775	Cellular component	chromosome, centromeric region
GO_0005886	Cellular component	plasma membrane
GO_0030018	Cellular component	Z disc
GO_0005813	Cellular component	centrosome
GO_0005829	Cellular component	cytosol
GO_0005737	Cellular component	cytoplasm
GO_0031430	Cellular component	M band
GO_0000159	Cellular component	protein phosphatase type 2A complex
GO_0005634	Cellular component	nucleus
GO_0004721	Molecular function	phosphoprotein phosphatase activity
GO_0019900	Molecular function	kinase binding
GO_0072542	Molecular function	protein phosphatase activator activity
GO_0019888	Molecular function	protein phosphatase regulator activity
GO_0005515	Molecular function	protein binding

IV. Literature review

[source]

Gene name	PPP2R5A
Protein name	Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit alpha isoform (PP2A B subunit isoform B'-alpha) (PP2A B subunit isoform B56-alpha) (PP2A B subunit isoform PR61-alpha) (PR61alpha) (PP2A B subunit isoform R5-alpha)
Synonyms
Description	FUNCTION: The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment.
Accessions	ENST00000261461.7 [Q15172-1] ENST00000537030.3 [Q15172-2] Q15172

PPP2R5A report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

IV. Literature review