Insufficient scRNA-seq data for expression of POU5F1 at single-cell level.
Insufficient scRNA-seq data for expression of POU5F1 at tissue level.
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
kidney | 100% | 1095.09 | 89 / 89 | 89% | 27.98 | 802 / 901 |
pancreas | 100% | 581.85 | 328 / 328 | 80% | 12.51 | 143 / 178 |
bladder | 95% | 783.76 | 20 / 21 | 67% | 9.87 | 338 / 504 |
intestine | 94% | 314.02 | 906 / 966 | 67% | 3.45 | 355 / 527 |
stomach | 96% | 576.36 | 343 / 359 | 62% | 2.88 | 177 / 286 |
uterus | 84% | 156.73 | 143 / 170 | 66% | 5.82 | 303 / 459 |
lung | 99% | 276.86 | 571 / 578 | 47% | 3.15 | 548 / 1155 |
esophagus | 78% | 77.93 | 1129 / 1445 | 66% | 4.99 | 121 / 183 |
liver | 100% | 326.56 | 225 / 226 | 35% | 2.17 | 141 / 406 |
prostate | 100% | 600.27 | 245 / 245 | 25% | 1.04 | 125 / 502 |
ovary | 31% | 24.44 | 56 / 180 | 76% | 8.04 | 328 / 430 |
breast | 94% | 103.58 | 433 / 459 | 9% | 0.47 | 106 / 1118 |
ureter | 0% | 0 | 0 / 0 | 100% | 10.14 | 1 / 1 |
spleen | 100% | 152.76 | 240 / 241 | 0% | 0 | 0 / 0 |
thymus | 91% | 77.11 | 595 / 653 | 6% | 0.23 | 39 / 605 |
heart | 92% | 109.93 | 796 / 861 | 0% | 0 | 0 / 0 |
adipose | 89% | 80.95 | 1073 / 1204 | 0% | 0 | 0 / 0 |
skin | 79% | 120.78 | 1424 / 1809 | 2% | 0.07 | 9 / 472 |
blood vessel | 80% | 70.47 | 1068 / 1335 | 0% | 0 | 0 / 0 |
tonsil | 0% | 0 | 0 / 0 | 69% | 4.06 | 31 / 45 |
muscle | 69% | 39.87 | 552 / 803 | 0% | 0 | 0 / 0 |
peripheral blood | 60% | 73.92 | 553 / 929 | 0% | 0 | 0 / 0 |
brain | 40% | 21.09 | 1068 / 2642 | 2% | 0.05 | 12 / 705 |
lymph node | 0% | 0 | 0 / 0 | 28% | 4.28 | 8 / 29 |
adrenal gland | 2% | 1.00 | 6 / 258 | 0% | 0.01 | 1 / 230 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
eye | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 80 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
GO_0010468 | Biological process | regulation of gene expression |
GO_0009786 | Biological process | regulation of asymmetric cell division |
GO_0006357 | Biological process | regulation of transcription by RNA polymerase II |
GO_1902894 | Biological process | negative regulation of miRNA transcription |
GO_0000122 | Biological process | negative regulation of transcription by RNA polymerase II |
GO_0006355 | Biological process | regulation of DNA-templated transcription |
GO_0009653 | Biological process | anatomical structure morphogenesis |
GO_0001824 | Biological process | blastocyst development |
GO_0009611 | Biological process | response to wounding |
GO_0001714 | Biological process | endodermal cell fate specification |
GO_0045944 | Biological process | positive regulation of transcription by RNA polymerase II |
GO_0035019 | Biological process | somatic stem cell population maintenance |
GO_0005739 | Cellular component | mitochondrion |
GO_0005654 | Cellular component | nucleoplasm |
GO_0005829 | Cellular component | cytosol |
GO_0005737 | Cellular component | cytoplasm |
GO_0005634 | Cellular component | nucleus |
GO_0003677 | Molecular function | DNA binding |
GO_0000978 | Molecular function | RNA polymerase II cis-regulatory region sequence-specific DNA binding |
GO_0001227 | Molecular function | DNA-binding transcription repressor activity, RNA polymerase II-specific |
GO_0000981 | Molecular function | DNA-binding transcription factor activity, RNA polymerase II-specific |
GO_0043565 | Molecular function | sequence-specific DNA binding |
GO_0000976 | Molecular function | transcription cis-regulatory region binding |
GO_1990837 | Molecular function | sequence-specific double-stranded DNA binding |
GO_0031625 | Molecular function | ubiquitin protein ligase binding |
GO_0003700 | Molecular function | DNA-binding transcription factor activity |
GO_0003723 | Molecular function | RNA binding |
GO_0035198 | Molecular function | miRNA binding |
GO_0005515 | Molecular function | protein binding |
Gene name | POU5F1 |
Protein name | POU domain transcription factor Oct4 isoform 3 POU domain protein POU class 5 homeobox 1 POU class 5 homeobox 1 transcript variant OCT4B4 POU domain, class 5, transcription factor 1 (Octamer-binding protein 3) (Oct-3) (Octamer-binding protein 4) (Oct-4) (Octamer-binding transcription factor 3) (OTF-3) POU class 5 homeobox 1 transcript variant OCT4B5 POU domain class 5 transcription factor 1 POU domain, class 5, transcription factor 1 POU class 5 homeobox 1 (POU class 5 homeobox 1 transcript variant OCT4B1) (POU class 5 homeobox 1 transcript variant OCT4B2) (POU class 5 homeobox 1 transcript variant OCT4B3) Putative truncated POU domain class 5 transcription factor 1 POU domain transcription factor OCT4 POU class 5 homeobox 1 transcript variant OCT4B6 |
Synonyms | OCT4 OCT3 OTF3 |
Description | FUNCTION: Transcription factor that binds to the octamer motif (5'-ATTTGCAT-3'). Forms a trimeric complex with SOX2 or SOX15 on DNA and controls the expression of a number of genes involved in embryonic development such as YES1, FGF4, UTF1 and ZFP206. Critical for early embryogenesis and for embryonic stem cell pluripotency. . |
Accessions | A7WPM2 A7WPM5 ENST00000259915.13 [Q01860-1] A7WPM6 ENST00000376243.8 [Q01860-2] B5B8N7 B5B8N9 A7WPL9 ENST00000454714.6 [Q01860-1] B5B8P7 A7WPN0 D5K9S1 D5K9R5 A7WPM8 A0A0K0KMS3 ENST00000429603.2 [Q01860-1] ENST00000441888.7 B5B8Q2 M1S623 ENST00000433063.6 [Q01860-1] C3RUE0 D5K9R1 B5B8P1 ENST00000433348.2 [Q01860-2] E9LR75 A7WPM9 A0A0K0KMI2 B5B8P8 ENST00000512818.5 D5K9R4 D5K9R7 D2IYK3 A0A1W2PP83 E9LR79 B5B8Q3 ENST00000429314.2 [Q01860-2] ENST00000471529.6 B5B8P9 ENST00000412166.6 [Q01860-2] D5K9R2 ENST00000383524.4 [Q01860-1] E9LR73 B5B8P2 B5B8Q4 F2Z381 ENST00000434616.2 [Q01860-1] ENST00000437747.6 [Q01860-1] D5K9Q9 B5B8P5 B5B8P6 D5K9R8 B5B8Q1 D5K9Q6 ENST00000640651.1 B5B8P0 D5K9R3 ENST00000513407.1 D5K9Q7 E9LR77 A7WPM3 A7WPM1 B5B8N8 Q01860 A0A0K0KMW9 ENST00000639883.1 A7WPM0 D5K9R9 ENST00000606567.6 ENST00000419095.2 [Q01860-2] A7WPM7 B5B8P3 B5B8Q0 B5B8P4 D5K9Q3 ENST00000451077.6 [Q01860-2] A7WPM4 |