PHF20L1 | OmnibusX

I. Expression across cell types

Name	Number of supported studies	Average coverage
endothelial cell	27 studies	27% ± 12%	Explore
natural killer cell	19 studies	20% ± 5%	Explore
classical monocyte	17 studies	24% ± 9%	Explore
fibroblast	14 studies	23% ± 6%	Explore
macrophage	12 studies	28% ± 11%	Explore
oligodendrocyte precursor cell	11 studies	32% ± 14%	Explore
oligodendrocyte	11 studies	31% ± 12%	Explore
GABAergic neuron	10 studies	43% ± 25%	Explore
glutamatergic neuron	10 studies	44% ± 26%	Explore
CD16-positive, CD56-dim natural killer cell, human	10 studies	20% ± 4%	Explore
microglial cell	10 studies	25% ± 9%	Explore
astrocyte	10 studies	31% ± 14%	Explore
endothelial cell of lymphatic vessel	9 studies	22% ± 5%	Explore
neutrophil	9 studies	23% ± 4%	Explore
pericyte	9 studies	23% ± 7%	Explore
smooth muscle cell	9 studies	18% ± 3%	Explore
plasmacytoid dendritic cell	9 studies	20% ± 6%	Explore
monocyte	8 studies	26% ± 9%	Explore
basal cell	8 studies	31% ± 10%	Explore
non-classical monocyte	8 studies	23% ± 7%	Explore
T cell	7 studies	21% ± 5%	Explore
CD16-negative, CD56-bright natural killer cell, human	7 studies	20% ± 3%	Explore
mature NK T cell	7 studies	18% ± 3%	Explore
neuron	7 studies	34% ± 14%	Explore
interneuron	7 studies	45% ± 24%	Explore
epithelial cell	7 studies	36% ± 18%	Explore
CD8-positive, alpha-beta memory T cell	7 studies	20% ± 4%	Explore
capillary endothelial cell	6 studies	17% ± 2%	Explore
myeloid cell	6 studies	25% ± 8%	Explore
CD8-positive, alpha-beta T cell	6 studies	20% ± 6%	Explore
adipocyte	6 studies	24% ± 5%	Explore
gamma-delta T cell	6 studies	26% ± 14%	Explore
respiratory goblet cell	5 studies	25% ± 7%	Explore
leukocyte	5 studies	22% ± 2%	Explore
naive B cell	5 studies	18% ± 3%	Explore
naive thymus-derived CD4-positive, alpha-beta T cell	5 studies	20% ± 4%	Explore
B cell	5 studies	23% ± 4%	Explore
dendritic cell	5 studies	29% ± 12%	Explore
regulatory T cell	5 studies	18% ± 4%	Explore
type I pneumocyte	4 studies	20% ± 3%	Explore
CD4-positive, alpha-beta memory T cell	4 studies	19% ± 4%	Explore
secretory cell	4 studies	29% ± 7%	Explore
naive thymus-derived CD8-positive, alpha-beta T cell	4 studies	20% ± 6%	Explore
CD4-positive, alpha-beta T cell	4 studies	25% ± 4%	Explore
effector memory CD8-positive, alpha-beta T cell	4 studies	21% ± 3%	Explore
granule cell	4 studies	29% ± 6%	Explore
amacrine cell	4 studies	24% ± 8%	Explore
retina horizontal cell	4 studies	25% ± 4%	Explore
cardiac muscle cell	4 studies	22% ± 2%	Explore
ciliated cell	4 studies	29% ± 9%	Explore
lymphocyte	4 studies	29% ± 7%	Explore
myofibroblast cell	4 studies	21% ± 6%	Explore
innate lymphoid cell	4 studies	19% ± 4%	Explore
goblet cell	4 studies	25% ± 13%	Explore
ionocyte	3 studies	30% ± 6%	Explore
effector CD8-positive, alpha-beta T cell	3 studies	17% ± 1%	Explore
conventional dendritic cell	3 studies	37% ± 15%	Explore
hematopoietic precursor cell	3 studies	26% ± 8%	Explore
glomerular endothelial cell	3 studies	19% ± 0%	Explore
abnormal cell	3 studies	26% ± 6%	Explore
GABAergic interneuron	3 studies	39% ± 8%	Explore
glial cell	3 studies	28% ± 9%	Explore
retinal ganglion cell	3 studies	25% ± 1%	Explore
club cell	3 studies	28% ± 3%	Explore
retinal cone cell	3 studies	22% ± 2%	Explore
mononuclear phagocyte	3 studies	23% ± 6%	Explore
Mueller cell	3 studies	24% ± 5%	Explore
OFF-bipolar cell	3 studies	18% ± 3%	Explore
ON-bipolar cell	3 studies	19% ± 3%	Explore
glycinergic amacrine cell	3 studies	21% ± 4%	Explore
endothelial cell of vascular tree	3 studies	22% ± 9%	Explore
hepatocyte	3 studies	27% ± 13%	Explore
platelet	3 studies	19% ± 3%	Explore
neural progenitor cell	3 studies	22% ± 5%	Explore
connective tissue cell	3 studies	19% ± 4%	Explore
brush cell	3 studies	29% ± 13%	Explore
group 3 innate lymphoid cell	3 studies	24% ± 8%	Explore
mural cell	3 studies	29% ± 12%	Explore

II. Expression across tissues

Name	Number of supported studies	Average coverage
brain	17 studies	34% ± 21%	Explore
lung	8 studies	24% ± 7%	Explore
peripheral blood	8 studies	23% ± 9%	Explore
eye	5 studies	24% ± 9%	Explore
liver	4 studies	25% ± 9%	Explore
adipose	4 studies	20% ± 3%	Explore
heart	3 studies	20% ± 3%	Explore
bone marrow	3 studies	17% ± 2%	Explore
intestine	3 studies	23% ± 7%	Explore

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
esophagus	100%	2496.64	1445 / 1445	100%	11.85	183 / 183
lung	100%	2826.05	578 / 578	100%	8.44	1153 / 1155
brain	100%	2160.13	2639 / 2642	100%	8.47	703 / 705
breast	100%	2654.50	459 / 459	99%	11.83	1112 / 1118
ovary	100%	3031.06	180 / 180	99%	8.40	425 / 430
thymus	100%	4972.29	653 / 653	98%	7.48	593 / 605
uterus	100%	3078.72	170 / 170	98%	7.30	448 / 459
bladder	100%	2610.48	21 / 21	97%	6.75	491 / 504
prostate	100%	2487.62	245 / 245	97%	6.21	489 / 502
pancreas	100%	1186.35	327 / 328	97%	5.55	173 / 178
stomach	100%	1781.25	359 / 359	97%	8.09	277 / 286
intestine	100%	2523.97	966 / 966	96%	6.84	507 / 527
kidney	100%	1767.69	89 / 89	93%	4.81	836 / 901
adrenal gland	100%	3172.59	258 / 258	92%	4.47	212 / 230
skin	100%	2562.77	1809 / 1809	91%	8.19	431 / 472
liver	100%	1342.27	226 / 226	84%	3.67	341 / 406
adipose	100%	2685.51	1204 / 1204	0%	0	0 / 0
blood vessel	100%	2635.24	1335 / 1335	0%	0	0 / 0
muscle	100%	2527.56	803 / 803	0%	0	0 / 0
spleen	100%	2851.32	241 / 241	0%	0	0 / 0
tonsil	0%	0	0 / 0	100%	7.10	45 / 45
ureter	0%	0	0 / 0	100%	4.11	1 / 1
heart	99%	2245.72	850 / 861	0%	0	0 / 0
peripheral blood	97%	2305.88	900 / 929	0%	0	0 / 0
lymph node	0%	0	0 / 0	90%	5.33	26 / 29
eye	0%	0	0 / 0	66%	4.71	53 / 80
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
gingiva	0%	0	0 / 0	0%	0	0 / 0
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0

III. Associated gene sets

GO_0042177	Biological process	negative regulation of protein catabolic process
GO_0032435	Biological process	negative regulation of proteasomal ubiquitin-dependent protein catabolic process
GO_0006357	Biological process	regulation of transcription by RNA polymerase II
GO_0005654	Cellular component	nucleoplasm
GO_0044545	Cellular component	NSL complex
GO_0140034	Molecular function	methylation-dependent protein binding
GO_0005515	Molecular function	protein binding
GO_0046872	Molecular function	metal ion binding

IV. Literature review

[source]

Gene name	PHF20L1
Protein name	PHD finger protein 20-like protein 1 PHD finger protein 20 like 1
Synonyms	CGI-72
Description	FUNCTION: Is a negative regulator of proteasomal degradation of a set of methylated proteins, including DNMT1 and SOX2 . Involved in the maintainance of embryonic stem cells pluripotency, through the regulation of SOX2 levels (By similarity). .
Accessions	A8MUE8 ENST00000622263.4 [A8MW92-1] F8W9L8 ENST00000521038.5 ENST00000337920.8 [A8MW92-2] A0A0A0MQS0 ENST00000395386.7 [A8MW92-1] ENST00000460236.5 ENST00000395376.5 A0A0D9SG14 H0YDF7 A8MW92 E5RK91 ENST00000485595.5 ENST00000395390.6 ENST00000220847.8 H0YC05 ENST00000486199.5 ENST00000395379.5 ENST00000522580.5 E9PM57 A8MXR8

PHF20L1 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

IV. Literature review