PHACTR2 report

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I. Expression across cell types

Cell ontologyData table

Name	Number of supported studies	Average coverage
endothelial cell	41 studies	39% ± 17%	Explore
fibroblast	34 studies	32% ± 17%	Explore
pericyte	21 studies	26% ± 13%	Explore
macrophage	18 studies	30% ± 11%	Explore
endothelial cell of lymphatic vessel	16 studies	31% ± 7%	Explore
capillary endothelial cell	15 studies	27% ± 11%	Explore
smooth muscle cell	14 studies	26% ± 9%	Explore
myofibroblast cell	13 studies	27% ± 9%	Explore
vein endothelial cell	13 studies	33% ± 12%	Explore
endothelial cell of vascular tree	13 studies	27% ± 9%	Explore
regulatory T cell	13 studies	30% ± 14%	Explore
type I pneumocyte	12 studies	37% ± 12%	Explore
ciliated cell	12 studies	26% ± 11%	Explore
endothelial cell of artery	11 studies	33% ± 7%	Explore
microglial cell	11 studies	30% ± 15%	Explore
T cell	10 studies	26% ± 10%	Explore
mucosal invariant T cell	10 studies	28% ± 12%	Explore
epithelial cell	10 studies	42% ± 22%	Explore
mast cell	8 studies	26% ± 8%	Explore
glutamatergic neuron	8 studies	37% ± 18%	Explore
myeloid cell	8 studies	30% ± 10%	Explore
club cell	8 studies	31% ± 13%	Explore
astrocyte	8 studies	32% ± 16%	Explore
type II pneumocyte	7 studies	26% ± 7%	Explore
connective tissue cell	7 studies	33% ± 12%	Explore
adipocyte	7 studies	24% ± 5%	Explore
dendritic cell	7 studies	33% ± 11%	Explore
basal cell	7 studies	30% ± 13%	Explore
monocyte	7 studies	32% ± 9%	Explore
respiratory goblet cell	6 studies	34% ± 14%	Explore
CD8-positive, alpha-beta T cell	6 studies	23% ± 6%	Explore
conventional dendritic cell	5 studies	25% ± 7%	Explore
mesothelial cell	5 studies	28% ± 12%	Explore
retina horizontal cell	5 studies	19% ± 2%	Explore
cardiac muscle cell	5 studies	26% ± 6%	Explore
lymphocyte	5 studies	33% ± 8%	Explore
T follicular helper cell	5 studies	20% ± 3%	Explore
GABAergic neuron	5 studies	46% ± 17%	Explore
natural killer cell	5 studies	23% ± 5%	Explore
squamous epithelial cell	4 studies	44% ± 16%	Explore
naive thymus-derived CD4-positive, alpha-beta T cell	4 studies	25% ± 7%	Explore
CD4-positive, alpha-beta T cell	4 studies	34% ± 5%	Explore
classical monocyte	4 studies	23% ± 7%	Explore
glomerular endothelial cell	4 studies	36% ± 7%	Explore
progenitor cell	4 studies	21% ± 4%	Explore
retinal bipolar neuron	4 studies	20% ± 1%	Explore
retinal pigment epithelial cell	4 studies	63% ± 17%	Explore
secretory cell	4 studies	31% ± 9%	Explore
interneuron	4 studies	41% ± 9%	Explore
CD4-positive, alpha-beta memory T cell	3 studies	19% ± 3%	Explore
type B pancreatic cell	3 studies	36% ± 17%	Explore
renal alpha-intercalated cell	3 studies	26% ± 8%	Explore
abnormal cell	3 studies	26% ± 12%	Explore
GABAergic interneuron	3 studies	26% ± 2%	Explore
neuron	3 studies	23% ± 7%	Explore
effector memory CD8-positive, alpha-beta T cell	3 studies	23% ± 9%	Explore
mononuclear phagocyte	3 studies	34% ± 4%	Explore
non-classical monocyte	3 studies	22% ± 2%	Explore
rod bipolar cell	3 studies	57% ± 8%	Explore
innate lymphoid cell	3 studies	20% ± 4%	Explore
endothelial cell of sinusoid	3 studies	33% ± 10%	Explore
megakaryocyte-erythroid progenitor cell	3 studies	28% ± 7%	Explore
leukocyte	3 studies	20% ± 3%	Explore
alveolar macrophage	3 studies	38% ± 6%	Explore
chondrocyte	3 studies	30% ± 2%	Explore
group 3 innate lymphoid cell	3 studies	23% ± 5%	Explore
transit amplifying cell	3 studies	30% ± 17%	Explore
mural cell	3 studies	35% ± 9%	Explore

II. Expression across tissues

sc-RNAseq dataData table

Name	Number of supported studies	Average coverage
lung	11 studies	26% ± 7%	Explore
brain	10 studies	30% ± 14%	Explore
heart	5 studies	26% ± 5%	Explore
placenta	4 studies	28% ± 9%	Explore
liver	4 studies	24% ± 12%	Explore
intestine	4 studies	25% ± 11%	Explore
adipose	3 studies	24% ± 7%	Explore

Bulk RNAseq dataData table

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
esophagus	100%	2534.64	1445 / 1445	99%	16.20	182 / 183
lung	100%	3540.64	578 / 578	99%	10.73	1141 / 1155
intestine	100%	1488.15	966 / 966	98%	10.31	518 / 527
stomach	100%	1722.86	359 / 359	98%	14.62	281 / 286
prostate	100%	2780.12	244 / 245	98%	11.07	494 / 502
breast	100%	2296.24	459 / 459	97%	10.03	1088 / 1118
bladder	100%	1775.71	21 / 21	97%	8.58	489 / 504
kidney	100%	1341.73	89 / 89	96%	11.36	861 / 901
uterus	100%	2360.98	170 / 170	95%	7.37	437 / 459
thymus	100%	3252.09	653 / 653	94%	15.28	567 / 605
ovary	100%	1784.87	180 / 180	93%	5.77	399 / 430
adrenal gland	100%	7431.87	258 / 258	76%	10.79	175 / 230
skin	98%	1249.15	1781 / 1809	76%	5.73	357 / 472
pancreas	75%	466.77	247 / 328	98%	10.31	174 / 178
brain	84%	564.97	2220 / 2642	79%	3.84	560 / 705
liver	94%	986.10	212 / 226	66%	3.38	266 / 406
adipose	100%	2782.15	1204 / 1204	0%	0	0 / 0
spleen	100%	2344.34	241 / 241	0%	0	0 / 0
ureter	0%	0	0 / 0	100%	4.24	1 / 1
blood vessel	100%	2354.42	1334 / 1335	0%	0	0 / 0
heart	100%	1863.57	860 / 861	0%	0	0 / 0
muscle	99%	997.53	795 / 803	0%	0	0 / 0
tonsil	0%	0	0 / 0	89%	7.59	40 / 45
lymph node	0%	0	0 / 0	86%	6.69	25 / 29
peripheral blood	56%	389.97	524 / 929	0%	0	0 / 0
eye	0%	0	0 / 0	25%	0.75	20 / 80
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
gingiva	0%	0	0 / 0	0%	0	0 / 0
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0