PHACTR1 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_0140059Biological processdendrite arborization
GO_0043149Biological processstress fiber assembly
GO_0048870Biological processcell motility
GO_0030036Biological processactin cytoskeleton organization
GO_0021987Biological processcerebral cortex development
GO_2001222Biological processregulation of neuron migration
GO_0031032Biological processactomyosin structure organization
GO_0005829Cellular componentcytosol
GO_0045202Cellular componentsynapse
GO_0005634Cellular componentnucleus
GO_0004864Molecular functionprotein phosphatase inhibitor activity
GO_0005515Molecular functionprotein binding
GO_0003779Molecular functionactin binding

IV. Literature review

[source]
Gene namePHACTR1
Protein namePhosphatase and actin regulator 1
Phosphatase and actin regulator
SynonymshCG_1818446
KIAA1733
RPEL1
DescriptionFUNCTION: Binds actin monomers (G actin) and plays a role in multiple processes including the regulation of actin cytoskeleton dynamics, actin stress fibers formation, cell motility and survival, formation of tubules by endothelial cells, and regulation of PPP1CA activity . Involved in the regulation of cortical neuron migration and dendrite arborization (By similarity). .

AccessionsQ4VY12
ENST00000676234.1
A0A6Q8PG87
A0A6Q8PFA8
H0Y7G2
ENST00000379335.8
ENST00000689548.1
ENST00000676159.1 [Q9C0D0-1]
ENST00000675203.2
A0A8I5KVE0
A0A8I5QJF9
ENST00000674637.1 [Q9C0D0-1]
ENST00000332995.12 [Q9C0D0-1]
ENST00000434977.1
ENST00000406205.7
H0Y3U1
ENST00000482982.2
ENST00000692995.1
Q9C0D0
ENST00000687600.1
ENST00000674595.1
A0A6Q8PGC2