Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
esophagus | 100% | 2126.17 | 1445 / 1445 | 100% | 33.81 | 183 / 183 |
stomach | 100% | 1962.81 | 359 / 359 | 99% | 36.00 | 283 / 286 |
intestine | 100% | 2141.12 | 966 / 966 | 99% | 32.10 | 520 / 527 |
pancreas | 100% | 2988.77 | 327 / 328 | 99% | 22.87 | 176 / 178 |
brain | 100% | 2228.14 | 2641 / 2642 | 98% | 21.19 | 694 / 705 |
prostate | 100% | 1630.10 | 244 / 245 | 98% | 14.64 | 493 / 502 |
lung | 100% | 2050.02 | 576 / 578 | 98% | 18.44 | 1133 / 1155 |
kidney | 100% | 1526.44 | 89 / 89 | 96% | 19.09 | 867 / 901 |
breast | 100% | 1934.26 | 459 / 459 | 96% | 14.94 | 1068 / 1118 |
thymus | 100% | 1767.03 | 651 / 653 | 95% | 12.18 | 575 / 605 |
adrenal gland | 100% | 1736.83 | 258 / 258 | 94% | 15.44 | 216 / 230 |
ovary | 100% | 2374.03 | 180 / 180 | 93% | 9.44 | 399 / 430 |
uterus | 100% | 2506.45 | 170 / 170 | 93% | 13.09 | 425 / 459 |
bladder | 100% | 2094.48 | 21 / 21 | 90% | 15.02 | 455 / 504 |
liver | 100% | 2153.75 | 226 / 226 | 88% | 13.14 | 359 / 406 |
skin | 100% | 2373.86 | 1806 / 1809 | 85% | 9.90 | 402 / 472 |
adipose | 100% | 2173.56 | 1204 / 1204 | 0% | 0 | 0 / 0 |
blood vessel | 100% | 2428.05 | 1335 / 1335 | 0% | 0 | 0 / 0 |
spleen | 100% | 1036.07 | 241 / 241 | 0% | 0 | 0 / 0 |
ureter | 0% | 0 | 0 / 0 | 100% | 4.34 | 1 / 1 |
muscle | 99% | 1117.66 | 793 / 803 | 0% | 0 | 0 / 0 |
peripheral blood | 97% | 1994.90 | 903 / 929 | 0% | 0 | 0 / 0 |
heart | 93% | 1105.79 | 805 / 861 | 0% | 0 | 0 / 0 |
tonsil | 0% | 0 | 0 / 0 | 89% | 10.39 | 40 / 45 |
eye | 0% | 0 | 0 / 0 | 61% | 5.17 | 49 / 80 |
lymph node | 0% | 0 | 0 / 0 | 52% | 3.95 | 15 / 29 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
GO_0022604 | Biological process | regulation of cell morphogenesis |
GO_0051560 | Biological process | mitochondrial calcium ion homeostasis |
GO_0007010 | Biological process | cytoskeleton organization |
GO_0006869 | Biological process | lipid transport |
GO_1990456 | Biological process | mitochondrion-endoplasmic reticulum membrane tethering |
GO_0044233 | Cellular component | mitochondria-associated endoplasmic reticulum membrane contact site |
GO_0016020 | Cellular component | membrane |
GO_0005789 | Cellular component | endoplasmic reticulum membrane |
GO_0005739 | Cellular component | mitochondrion |
GO_0005515 | Molecular function | protein binding |
GO_0008289 | Molecular function | lipid binding |
GO_0046872 | Molecular function | metal ion binding |
Gene name | PDZD8 |
Protein name | PDZ domain-containing protein 8 (Sarcoma antigen NY-SAR-84/NY-SAR-104) |
Synonyms | PDZK8 |
Description | FUNCTION: Molecular tethering protein that connects endoplasmic reticulum and mitochondria membranes . PDZD8-dependent endoplasmic reticulum-mitochondria membrane tethering is essential for endoplasmic reticulum-mitochondria Ca(2+) transfer . In neurons, involved in the regulation of dendritic Ca(2+) dynamics by regulating mitochondrial Ca(2+) uptake in neurons . Plays an indirect role in the regulation of cell morphology and cytoskeletal organization . May inhibit herpes simplex virus 1 infection at an early stage . . |
Accessions | ENST00000334464.7 Q8NEN9 |