Name | Number of supported studies | Average coverage | |
---|---|---|---|
endothelial cell | 15 studies | 29% ± 9% | |
astrocyte | 11 studies | 32% ± 16% | |
microglial cell | 11 studies | 31% ± 12% | |
fibroblast | 10 studies | 26% ± 8% | |
macrophage | 9 studies | 29% ± 9% | |
adipocyte | 9 studies | 32% ± 6% | |
GABAergic neuron | 8 studies | 31% ± 17% | |
oligodendrocyte precursor cell | 8 studies | 29% ± 12% | |
epithelial cell | 7 studies | 27% ± 15% | |
oligodendrocyte | 7 studies | 29% ± 11% | |
smooth muscle cell | 7 studies | 19% ± 3% | |
interneuron | 6 studies | 38% ± 20% | |
ciliated cell | 6 studies | 26% ± 9% | |
T cell | 6 studies | 22% ± 6% | |
endothelial cell of lymphatic vessel | 6 studies | 27% ± 6% | |
type II pneumocyte | 6 studies | 36% ± 12% | |
pericyte | 6 studies | 22% ± 6% | |
glutamatergic neuron | 5 studies | 42% ± 20% | |
cardiac muscle cell | 5 studies | 27% ± 6% | |
type I pneumocyte | 5 studies | 33% ± 8% | |
basal cell | 5 studies | 31% ± 17% | |
dendritic cell | 4 studies | 21% ± 1% | |
myeloid cell | 4 studies | 30% ± 6% | |
club cell | 4 studies | 36% ± 11% | |
monocyte | 4 studies | 31% ± 8% | |
GABAergic interneuron | 3 studies | 19% ± 3% | |
granule cell | 3 studies | 23% ± 5% | |
neuron | 3 studies | 39% ± 19% | |
plasma cell | 3 studies | 29% ± 10% | |
mast cell | 3 studies | 22% ± 7% | |
Mueller cell | 3 studies | 24% ± 7% | |
retinal rod cell | 3 studies | 21% ± 4% | |
endothelial cell of vascular tree | 3 studies | 25% ± 10% | |
hepatocyte | 3 studies | 52% ± 17% | |
B cell | 3 studies | 25% ± 7% | |
alveolar macrophage | 3 studies | 39% ± 7% | |
respiratory goblet cell | 3 studies | 34% ± 14% | |
lymphocyte | 3 studies | 30% ± 6% | |
goblet cell | 3 studies | 39% ± 18% | |
transit amplifying cell | 3 studies | 35% ± 25% | |
mucus secreting cell | 3 studies | 32% ± 11% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
esophagus | 100% | 855.59 | 1445 / 1445 | 100% | 16.48 | 183 / 183 |
liver | 100% | 1398.91 | 226 / 226 | 100% | 17.10 | 406 / 406 |
prostate | 100% | 1052.00 | 245 / 245 | 100% | 39.98 | 502 / 502 |
stomach | 100% | 737.66 | 359 / 359 | 100% | 20.13 | 286 / 286 |
intestine | 100% | 975.19 | 966 / 966 | 100% | 22.37 | 526 / 527 |
lung | 100% | 780.64 | 577 / 578 | 100% | 16.36 | 1153 / 1155 |
thymus | 100% | 1110.16 | 653 / 653 | 100% | 25.82 | 602 / 605 |
breast | 100% | 916.97 | 459 / 459 | 99% | 20.73 | 1111 / 1118 |
uterus | 100% | 819.54 | 170 / 170 | 99% | 15.64 | 456 / 459 |
bladder | 100% | 887.95 | 21 / 21 | 99% | 17.37 | 499 / 504 |
kidney | 100% | 1379.31 | 89 / 89 | 99% | 19.55 | 891 / 901 |
brain | 99% | 457.80 | 2615 / 2642 | 100% | 16.19 | 704 / 705 |
ovary | 100% | 817.43 | 180 / 180 | 99% | 12.96 | 424 / 430 |
pancreas | 99% | 494.24 | 326 / 328 | 99% | 14.39 | 176 / 178 |
adrenal gland | 100% | 2270.86 | 258 / 258 | 96% | 15.98 | 221 / 230 |
skin | 100% | 914.89 | 1808 / 1809 | 95% | 14.95 | 449 / 472 |
adipose | 100% | 881.73 | 1204 / 1204 | 0% | 0 | 0 / 0 |
lymph node | 0% | 0 | 0 / 0 | 100% | 12.81 | 29 / 29 |
spleen | 100% | 700.54 | 241 / 241 | 0% | 0 | 0 / 0 |
tonsil | 0% | 0 | 0 / 0 | 100% | 15.38 | 45 / 45 |
blood vessel | 100% | 785.12 | 1334 / 1335 | 0% | 0 | 0 / 0 |
muscle | 100% | 745.67 | 802 / 803 | 0% | 0 | 0 / 0 |
heart | 97% | 890.61 | 831 / 861 | 0% | 0 | 0 / 0 |
eye | 0% | 0 | 0 / 0 | 84% | 9.33 | 67 / 80 |
peripheral blood | 74% | 406.91 | 691 / 929 | 0% | 0 | 0 / 0 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
GO_0021549 | Biological process | cerebellum development |
GO_0008299 | Biological process | isoprenoid biosynthetic process |
GO_0050878 | Biological process | regulation of body fluid levels |
GO_0006744 | Biological process | ubiquinone biosynthetic process |
GO_0032478 | Cellular component | heterotetrameric polyprenyl diphosphate synthase complex |
GO_0005829 | Cellular component | cytosol |
GO_0005759 | Cellular component | mitochondrial matrix |
GO_1990234 | Cellular component | transferase complex |
GO_0046982 | Molecular function | protein heterodimerization activity |
GO_0052923 | Molecular function | all-trans-nonaprenyl-diphosphate synthase (geranyl-diphosphate specific) activity |
GO_0005515 | Molecular function | protein binding |
GO_0004659 | Molecular function | prenyltransferase activity |
GO_0097269 | Molecular function | all-trans-decaprenyl-diphosphate synthase activity |
Gene name | PDSS2 |
Protein name | Decaprenyl diphosphate synthase subunit 2 All trans-polyprenyl-diphosphate synthase PDSS2 (All-trans-decaprenyl-diphosphate synthase subunit 2) (EC 2.5.1.91) (Candidate tumor suppressor protein) (Decaprenyl pyrophosphate synthase subunit 2) (Decaprenyl-diphosphate synthase subunit 2) (Solanesyl-diphosphate synthase subunit 2) |
Synonyms | DLP1 C6orf210 |
Description | FUNCTION: Heterotetrameric enzyme that catalyzes the condensation of farnesyl diphosphate (FPP), which acts as a primer, and isopentenyl diphosphate (IPP) to produce prenyl diphosphates of varying chain lengths and participates in the determination of the side chain of ubiquinone . Supplies nona and decaprenyl diphosphate, the precursors for the side chain of the isoprenoid quinones ubiquinone-9 (Q9) and ubiquinone-10 (Q10) respectively . The enzyme adds isopentenyl diphosphate molecules sequentially to farnesyl diphosphate with trans stereochemistry . May play a role during cerebellar development (By similarity). May regulate mitochondrial respiratory chain function (By similarity). . |
Accessions | Q5JRD6 Q86YH6 ENST00000369031.4 [Q86YH6-2] ENST00000369037.9 [Q86YH6-1] ENST00000449027.1 |