PARD6B report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_0007043Biological processcell-cell junction assembly
GO_0007163Biological processestablishment or maintenance of cell polarity
GO_0051301Biological processcell division
GO_0060341Biological processregulation of cellular localization
GO_0065003Biological processprotein-containing complex assembly
GO_0007098Biological processcentrosome cycle
GO_0007409Biological processaxonogenesis
GO_0030334Biological processregulation of cell migration
GO_0045197Biological processestablishment or maintenance of epithelial cell apical/basal polarity
GO_0016324Cellular componentapical plasma membrane
GO_0070160Cellular componenttight junction
GO_0005886Cellular componentplasma membrane
GO_0070062Cellular componentextracellular exosome
GO_0005829Cellular componentcytosol
GO_0005938Cellular componentcell cortex
GO_0120157Cellular componentPAR polarity complex
GO_0005923Cellular componentbicellular tight junction
GO_0005634Cellular componentnucleus
GO_0005515Molecular functionprotein binding

IV. Literature review

[source]
Gene namePARD6B
Protein namePartitioning defective 6 homolog beta (PAR-6 beta) (PAR-6B)
SynonymsPAR6B
DescriptionFUNCTION: Adapter protein involved in asymmetrical cell division and cell polarization processes. Probably involved in formation of epithelial tight junctions. Association with PARD3 may prevent the interaction of PARD3 with F11R/JAM1, thereby preventing tight junction assembly. The PARD6-PARD3 complex links GTP-bound Rho small GTPases to atypical protein kinase C proteins.

AccessionsQ9BYG5
ENST00000371610.7 [Q9BYG5-1]
ENST00000396039.1 [Q9BYG5-2]