PALLD report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_0003382Biological processepithelial cell morphogenesis
GO_0007010Biological processcytoskeleton organization
GO_0030036Biological processactin cytoskeleton organization
GO_0007156Biological processhomophilic cell adhesion via plasma membrane adhesion molecules
GO_0003334Biological processkeratinocyte development
GO_0016477Biological processcell migration
GO_0007411Biological processaxon guidance
GO_0070593Biological processdendrite self-avoidance
GO_0001726Cellular componentruffle
GO_0005886Cellular componentplasma membrane
GO_0030018Cellular componentZ disc
GO_0005739Cellular componentmitochondrion
GO_0002102Cellular componentpodosome
GO_0005884Cellular componentactin filament
GO_0005925Cellular componentfocal adhesion
GO_0001725Cellular componentstress fiber
GO_0015629Cellular componentactin cytoskeleton
GO_0005829Cellular componentcytosol
GO_0030426Cellular componentgrowth cone
GO_0060076Cellular componentexcitatory synapse
GO_0030424Cellular componentaxon
GO_0030027Cellular componentlamellipodium
GO_0005634Cellular componentnucleus
GO_0098632Molecular functioncell-cell adhesion mediator activity
GO_0051371Molecular functionmuscle alpha-actinin binding
GO_0003779Molecular functionactin binding
GO_0005515Molecular functionprotein binding

IV. Literature review

[source]
Gene namePALLD
Protein namePalladin, cytoskeletal associated protein
Palladin (SIH002) (Sarcoma antigen NY-SAR-77)
Alternative protein PALLD
SynonymshCG_2026123
CGI-151
KIAA0992
DescriptionFUNCTION: Cytoskeletal protein required for organization of normal actin cytoskeleton. Roles in establishing cell morphology, motility, cell adhesion and cell-extracellular matrix interactions in a variety of cell types. May function as a scaffolding molecule with the potential to influence both actin polymerization and the assembly of existing actin filaments into higher-order arrays. Binds to proteins that bind to either monomeric or filamentous actin. Localizes at sites where active actin remodeling takes place, such as lamellipodia and membrane ruffles. Different isoforms may have functional differences. Involved in the control of morphological and cytoskeletal changes associated with dendritic cell maturation. Involved in targeting ACTN to specific subcellular foci. .

AccessionsA0A3B3ISX8
ENST00000704822.1
ENST00000510998.5
A0A994J7A4
ENST00000504519.5
ENST00000649826.1
ENST00000512127.5 [Q8WX93-8]
F8WA26
ENST00000505667.6 [Q8WX93-9]
D6RBH5
H0Y952
B2RTX2
D6R9Z5
ENST00000503457.1
Q8WX93
ENST00000261509.10 [Q8WX93-2]
ENST00000507735.6 [Q8WX93-4]
ENST00000511948.1
H0YA05
ENST00000513245.5
D6RBB1
D6R948
D6R9F5
L0R8B3
ENST00000393726.7
ENST00000503290.1
ENST00000508898.5