NSF report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_0001921Biological processpositive regulation of receptor recycling
GO_0006813Biological processpotassium ion transport
GO_0006886Biological processintracellular protein transport
GO_0017157Biological processregulation of exocytosis
GO_0045732Biological processpositive regulation of protein catabolic process
GO_0035494Biological processSNARE complex disassembly
GO_0016192Biological processvesicle-mediated transport
GO_0006887Biological processexocytosis
GO_0006891Biological processintra-Golgi vesicle-mediated transport
GO_0043001Biological processGolgi to plasma membrane protein transport
GO_0045026Biological processplasma membrane fusion
GO_0005795Cellular componentGolgi stack
GO_0005886Cellular componentplasma membrane
GO_0043198Cellular componentdendritic shaft
GO_0005794Cellular componentGolgi apparatus
GO_0005829Cellular componentcytosol
GO_0014069Cellular componentpostsynaptic density
GO_0005765Cellular componentlysosomal membrane
GO_0140545Molecular functionATP-dependent protein disaggregase activity
GO_0044877Molecular functionprotein-containing complex binding
GO_0019901Molecular functionprotein kinase binding
GO_0017075Molecular functionsyntaxin-1 binding
GO_0030165Molecular functionPDZ domain binding
GO_0000149Molecular functionSNARE binding
GO_0046872Molecular functionmetal ion binding
GO_0005524Molecular functionATP binding
GO_0035255Molecular functionionotropic glutamate receptor binding
GO_0005515Molecular functionprotein binding
GO_0016887Molecular functionATP hydrolysis activity

IV. Literature review

[source]
Gene nameNSF
Protein nameVesicle-fusing ATPase
Vesicle-fusing ATPase (EC 3.6.4.6)
Vesicle-fusing ATPase (EC 3.6.4.6) (N-ethylmaleimide-sensitive fusion protein) (NEM-sensitive fusion protein) (Vesicular-fusion protein NSF)
Synonyms
DescriptionFUNCTION: Required for vesicle-mediated transport. Catalyzes the fusion of transport vesicles within the Golgi cisternae. Is also required for transport from the endoplasmic reticulum to the Golgi stack. Seems to function as a fusion protein required for the delivery of cargo proteins to all compartments of the Golgi stack independent of vesicle origin. Interaction with AMPAR subunit GRIA2 leads to influence GRIA2 membrane cycling (By similarity). .

FUNCTION: Required for vesicle-mediated transport. Catalyzes the fusion of transport vesicles within the Golgi cisternae. Is also required for transport from the endoplasmic reticulum to the Golgi stack. Seems to function as a fusion protein required for the delivery of cargo proteins to all compartments of the Golgi stack independent of vesicle origin. .

FUNCTION: Required for vesicle-mediated transport. Catalyzes the fusion of transport vesicles within the Golgi cisternae. Is also required for transport from the endoplasmic reticulum to the Golgi stack. Seems to function as a fusion protein required for the delivery of cargo proteins to all compartments of the Golgi stack independent of vesicle origin. .

FUNCTION: Required for vesicle-mediated transport. Catalyzes the fusion of transport vesicles within the Golgi cisternae. Is also required for transport from the endoplasmic reticulum to the Golgi stack. Seems to function as a fusion protein required for the delivery of cargo proteins to all compartments of the Golgi stack independent of vesicle origin. .

FUNCTION: Required for vesicle-mediated transport. Catalyzes the fusion of transport vesicles within the Golgi cisternae. Is also required for transport from the endoplasmic reticulum to the Golgi stack. Seems to function as a fusion protein required for the delivery of cargo proteins to all compartments of the Golgi stack independent of vesicle origin. .

FUNCTION: Required for vesicle-mediated transport. Catalyzes the fusion of transport vesicles within the Golgi cisternae. Is also required for transport from the endoplasmic reticulum to the Golgi stack. Seems to function as a fusion protein required for the delivery of cargo proteins to all compartments of the Golgi stack independent of vesicle origin. .

FUNCTION: Required for vesicle-mediated transport. Catalyzes the fusion of transport vesicles within the Golgi cisternae. Is also required for transport from the endoplasmic reticulum to the Golgi stack. Seems to function as a fusion protein required for the delivery of cargo proteins to all compartments of the Golgi stack independent of vesicle origin. .

FUNCTION: Required for vesicle-mediated transport. Catalyzes the fusion of transport vesicles within the Golgi cisternae. Is also required for transport from the endoplasmic reticulum to the Golgi stack. Seems to function as a fusion protein required for the delivery of cargo proteins to all compartments of the Golgi stack independent of vesicle origin. .

FUNCTION: Required for vesicle-mediated transport. Catalyzes the fusion of transport vesicles within the Golgi cisternae. Is also required for transport from the endoplasmic reticulum to the Golgi stack. Seems to function as a fusion protein required for the delivery of cargo proteins to all compartments of the Golgi stack independent of vesicle origin. .

FUNCTION: Required for vesicle-mediated transport. Catalyzes the fusion of transport vesicles within the Golgi cisternae. Is also required for transport from the endoplasmic reticulum to the Golgi stack. Seems to function as a fusion protein required for the delivery of cargo proteins to all compartments of the Golgi stack independent of vesicle origin. .

FUNCTION: Required for vesicle-mediated transport. Catalyzes the fusion of transport vesicles within the Golgi cisternae. Is also required for transport from the endoplasmic reticulum to the Golgi stack. Seems to function as a fusion protein required for the delivery of cargo proteins to all compartments of the Golgi stack independent of vesicle origin. .

FUNCTION: Required for vesicle-mediated transport. Catalyzes the fusion of transport vesicles within the Golgi cisternae. Is also required for transport from the endoplasmic reticulum to the Golgi stack. Seems to function as a fusion protein required for the delivery of cargo proteins to all compartments of the Golgi stack independent of vesicle origin. .

FUNCTION: Required for vesicle-mediated transport. Catalyzes the fusion of transport vesicles within the Golgi cisternae. Is also required for transport from the endoplasmic reticulum to the Golgi stack. Seems to function as a fusion protein required for the delivery of cargo proteins to all compartments of the Golgi stack independent of vesicle origin. .

FUNCTION: Required for vesicle-mediated transport. Catalyzes the fusion of transport vesicles within the Golgi cisternae. Is also required for transport from the endoplasmic reticulum to the Golgi stack. Seems to function as a fusion protein required for the delivery of cargo proteins to all compartments of the Golgi stack independent of vesicle origin. .

FUNCTION: Required for vesicle-mediated transport. Catalyzes the fusion of transport vesicles within the Golgi cisternae. Is also required for transport from the endoplasmic reticulum to the Golgi stack. Seems to function as a fusion protein required for the delivery of cargo proteins to all compartments of the Golgi stack independent of vesicle origin. .

FUNCTION: Required for vesicle-mediated transport. Catalyzes the fusion of transport vesicles within the Golgi cisternae. Is also required for transport from the endoplasmic reticulum to the Golgi stack. Seems to function as a fusion protein required for the delivery of cargo proteins to all compartments of the Golgi stack independent of vesicle origin. .

FUNCTION: Required for vesicle-mediated transport. Catalyzes the fusion of transport vesicles within the Golgi cisternae. Is also required for transport from the endoplasmic reticulum to the Golgi stack. Seems to function as a fusion protein required for the delivery of cargo proteins to all compartments of the Golgi stack independent of vesicle origin. .

AccessionsP46459
A0A994J5X9
ENST00000706398.1
ENST00000576040.6
ENST00000620290.2 [P46459-1]
ENST00000706396.1
I3L2G1
ENST00000632862.1
ENST00000631254.2
I3L0N3
ENST00000706391.1
ENST00000633834.1
ENST00000632852.1
ENST00000706393.1
ENST00000628506.2
ENST00000465370.2
A0A994J5Y2
ENST00000398238.8 [P46459-1]
ENST00000571864.6
ENST00000627873.2
ENST00000611398.3 [P46459-1]
ENST00000706397.1
K7EQD6
ENST00000706392.1 [P46459-1]
ENST00000632125.1
ENST00000575068.5
ENST00000706395.1
A0A0J9YXN6
A0A994J5C9
A0A994J855
ENST00000706401.1
A0A994J5X2
ENST00000626883.2
A0A994J7T3
A0A0G2JRU0
A0A994J5C5
ENST00000628895.2
ENST00000706399.1
Q96D47
ENST00000628495.1
I3L4Q9
ENST00000706373.1
A0A994J5K9
B4DH19
ENST00000633653.1
ENST00000706400.1
I3L0L3