Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| endothelial cell | 7 studies | 20% ± 7% | |
| epithelial cell | 6 studies | 31% ± 15% | |
| CD16-negative, CD56-bright natural killer cell, human | 5 studies | 18% ± 2% | |
| CD4-positive, alpha-beta T cell | 4 studies | 22% ± 3% | |
| CD8-positive, alpha-beta T cell | 4 studies | 21% ± 1% | |
| fibroblast | 4 studies | 21% ± 6% | |
| basal cell | 4 studies | 25% ± 10% | |
| B cell | 3 studies | 22% ± 3% | |
| CD16-positive, CD56-dim natural killer cell, human | 3 studies | 18% ± 3% | |
| hematopoietic precursor cell | 3 studies | 25% ± 5% | |
| non-classical monocyte | 3 studies | 34% ± 9% | |
| neuron | 3 studies | 27% ± 13% | |
| precursor B cell | 3 studies | 18% ± 1% | |
| dendritic cell | 3 studies | 37% ± 7% | |
| natural killer cell | 3 studies | 22% ± 1% | |
| plasmacytoid dendritic cell | 3 studies | 23% ± 3% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| esophagus | 100% | 4306.44 | 1445 / 1445 | 100% | 56.97 | 183 / 183 |
| pancreas | 100% | 2857.14 | 328 / 328 | 100% | 45.66 | 178 / 178 |
| skin | 100% | 6158.85 | 1809 / 1809 | 100% | 83.79 | 472 / 472 |
| uterus | 100% | 4117.80 | 170 / 170 | 100% | 72.25 | 458 / 459 |
| thymus | 100% | 3770.22 | 653 / 653 | 100% | 44.24 | 602 / 605 |
| intestine | 100% | 3618.80 | 966 / 966 | 99% | 66.26 | 524 / 527 |
| prostate | 100% | 3962.40 | 245 / 245 | 99% | 62.56 | 499 / 502 |
| breast | 100% | 3834.00 | 459 / 459 | 99% | 59.68 | 1111 / 1118 |
| ovary | 100% | 3432.03 | 180 / 180 | 99% | 41.36 | 427 / 430 |
| lung | 100% | 3405.83 | 577 / 578 | 99% | 57.02 | 1146 / 1155 |
| bladder | 100% | 4414.14 | 21 / 21 | 99% | 70.84 | 498 / 504 |
| stomach | 100% | 3051.67 | 359 / 359 | 99% | 56.05 | 282 / 286 |
| kidney | 100% | 3235.43 | 89 / 89 | 98% | 34.19 | 884 / 901 |
| brain | 98% | 2854.01 | 2595 / 2642 | 100% | 45.40 | 703 / 705 |
| liver | 100% | 2623.33 | 226 / 226 | 98% | 31.79 | 397 / 406 |
| adrenal gland | 100% | 3047.15 | 258 / 258 | 94% | 35.09 | 216 / 230 |
| adipose | 100% | 3551.18 | 1204 / 1204 | 0% | 0 | 0 / 0 |
| eye | 0% | 0 | 0 / 0 | 100% | 59.25 | 80 / 80 |
| lymph node | 0% | 0 | 0 / 0 | 100% | 61.93 | 29 / 29 |
| muscle | 100% | 5401.72 | 803 / 803 | 0% | 0 | 0 / 0 |
| spleen | 100% | 3877.94 | 241 / 241 | 0% | 0 | 0 / 0 |
| tonsil | 0% | 0 | 0 / 0 | 100% | 63.63 | 45 / 45 |
| ureter | 0% | 0 | 0 / 0 | 100% | 45.92 | 1 / 1 |
| blood vessel | 100% | 3368.86 | 1334 / 1335 | 0% | 0 | 0 / 0 |
| heart | 97% | 2681.96 | 836 / 861 | 0% | 0 | 0 / 0 |
| peripheral blood | 85% | 2422.08 | 792 / 929 | 0% | 0 | 0 / 0 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| GO_0034644 | Biological process | cellular response to UV |
| GO_0002903 | Biological process | negative regulation of B cell apoptotic process |
| GO_0000122 | Biological process | negative regulation of transcription by RNA polymerase II |
| GO_0042273 | Biological process | ribosomal large subunit biogenesis |
| GO_0006915 | Biological process | apoptotic process |
| GO_2001243 | Biological process | negative regulation of intrinsic apoptotic signaling pathway |
| GO_0045815 | Biological process | transcription initiation-coupled chromatin remodeling |
| GO_0005730 | Cellular component | nucleolus |
| GO_0030690 | Cellular component | Noc1p-Noc2p complex |
| GO_0005654 | Cellular component | nucleoplasm |
| GO_0030691 | Cellular component | Noc2p-Noc3p complex |
| GO_0005829 | Cellular component | cytosol |
| GO_0005694 | Cellular component | chromosome |
| GO_0005634 | Cellular component | nucleus |
| GO_0140297 | Molecular function | DNA-binding transcription factor binding |
| GO_0042393 | Molecular function | histone binding |
| GO_0003682 | Molecular function | chromatin binding |
| GO_0003714 | Molecular function | transcription corepressor activity |
| GO_0003723 | Molecular function | RNA binding |
| GO_0031491 | Molecular function | nucleosome binding |
| GO_0005515 | Molecular function | protein binding |
| Gene name | NOC2L |
| Protein name | Nucleolar complex protein 2 homolog (Protein NOC2 homolog) (NOC2-like protein) (Novel INHAT repressor) |
| Synonyms | NIR |
| Description | FUNCTION: Acts as an inhibitor of histone acetyltransferase activity; prevents acetylation of all core histones by the EP300/p300 histone acetyltransferase at p53/TP53-regulated target promoters in a histone deacetylases (HDAC)-independent manner. Acts as a transcription corepressor of p53/TP53- and TP63-mediated transactivation of the p21/CDKN1A promoter. Involved in the regulation of p53/TP53-dependent apoptosis. Associates together with TP63 isoform TA*-gamma to the p21/CDKN1A promoter. . |
| Accessions | ENST00000327044.7 Q9Y3T9 |