Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| endothelial cell | 14 studies | 24% ± 8% | |
| astrocyte | 8 studies | 28% ± 13% | |
| macrophage | 7 studies | 23% ± 4% | |
| microglial cell | 6 studies | 23% ± 6% | |
| epithelial cell | 6 studies | 31% ± 11% | |
| classical monocyte | 5 studies | 23% ± 6% | |
| pericyte | 5 studies | 21% ± 3% | |
| smooth muscle cell | 5 studies | 18% ± 2% | |
| cardiac muscle cell | 5 studies | 27% ± 5% | |
| oligodendrocyte precursor cell | 5 studies | 33% ± 17% | |
| interneuron | 5 studies | 37% ± 17% | |
| oligodendrocyte | 5 studies | 26% ± 9% | |
| conventional dendritic cell | 4 studies | 27% ± 11% | |
| hematopoietic precursor cell | 4 studies | 17% ± 1% | |
| non-classical monocyte | 4 studies | 26% ± 7% | |
| myeloid cell | 4 studies | 23% ± 5% | |
| fibroblast | 4 studies | 19% ± 4% | |
| regulatory T cell | 4 studies | 19% ± 1% | |
| GABAergic neuron | 4 studies | 42% ± 15% | |
| glutamatergic neuron | 4 studies | 53% ± 8% | |
| dendritic cell | 4 studies | 28% ± 8% | |
| endothelial cell of lymphatic vessel | 4 studies | 19% ± 2% | |
| monocyte | 4 studies | 19% ± 3% | |
| goblet cell | 4 studies | 24% ± 9% | |
| natural killer cell | 3 studies | 19% ± 1% | |
| ciliated cell | 3 studies | 20% ± 0% | |
| lymphocyte | 3 studies | 19% ± 3% | |
| abnormal cell | 3 studies | 23% ± 7% | |
| transit amplifying cell | 3 studies | 24% ± 10% | |
| adipocyte | 3 studies | 19% ± 3% | |
| neuron | 3 studies | 29% ± 9% | |
| CD8-positive, alpha-beta T cell | 3 studies | 17% ± 1% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| esophagus | 100% | 2732.89 | 1445 / 1445 | 100% | 29.06 | 183 / 183 |
| intestine | 100% | 3019.02 | 966 / 966 | 100% | 23.95 | 527 / 527 |
| liver | 100% | 1960.12 | 226 / 226 | 100% | 21.13 | 406 / 406 |
| ovary | 100% | 3261.77 | 180 / 180 | 100% | 42.62 | 430 / 430 |
| prostate | 100% | 2886.66 | 245 / 245 | 100% | 28.23 | 502 / 502 |
| skin | 100% | 3281.54 | 1809 / 1809 | 100% | 34.01 | 472 / 472 |
| stomach | 100% | 2392.88 | 359 / 359 | 100% | 24.15 | 286 / 286 |
| thymus | 100% | 3688.28 | 653 / 653 | 100% | 33.53 | 605 / 605 |
| uterus | 100% | 3392.53 | 170 / 170 | 100% | 37.88 | 459 / 459 |
| kidney | 100% | 2750.42 | 89 / 89 | 100% | 24.76 | 900 / 901 |
| lung | 100% | 2479.63 | 577 / 578 | 100% | 27.51 | 1155 / 1155 |
| breast | 100% | 3092.27 | 459 / 459 | 100% | 30.53 | 1116 / 1118 |
| bladder | 100% | 2876.00 | 21 / 21 | 100% | 28.35 | 503 / 504 |
| pancreas | 100% | 1650.66 | 327 / 328 | 100% | 23.01 | 178 / 178 |
| brain | 100% | 2139.99 | 2630 / 2642 | 100% | 25.93 | 705 / 705 |
| adrenal gland | 100% | 2434.85 | 258 / 258 | 99% | 17.84 | 228 / 230 |
| adipose | 100% | 2582.77 | 1204 / 1204 | 0% | 0 | 0 / 0 |
| blood vessel | 100% | 2670.34 | 1335 / 1335 | 0% | 0 | 0 / 0 |
| lymph node | 0% | 0 | 0 / 0 | 100% | 31.45 | 29 / 29 |
| muscle | 100% | 3320.38 | 803 / 803 | 0% | 0 | 0 / 0 |
| spleen | 100% | 4113.18 | 241 / 241 | 0% | 0 | 0 / 0 |
| tonsil | 0% | 0 | 0 / 0 | 100% | 31.97 | 45 / 45 |
| ureter | 0% | 0 | 0 / 0 | 100% | 28.76 | 1 / 1 |
| heart | 99% | 2747.24 | 856 / 861 | 0% | 0 | 0 / 0 |
| peripheral blood | 99% | 3854.75 | 923 / 929 | 0% | 0 | 0 / 0 |
| eye | 0% | 0 | 0 / 0 | 99% | 28.57 | 79 / 80 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| GO_0006457 | Biological process | protein folding |
| GO_0006355 | Biological process | regulation of DNA-templated transcription |
| GO_0045944 | Biological process | positive regulation of transcription by RNA polymerase II |
| GO_0006357 | Biological process | regulation of transcription by RNA polymerase II |
| GO_0090575 | Cellular component | RNA polymerase II transcription regulator complex |
| GO_0032993 | Cellular component | protein-DNA complex |
| GO_0005654 | Cellular component | nucleoplasm |
| GO_0000785 | Cellular component | chromatin |
| GO_0016602 | Cellular component | CCAAT-binding factor complex |
| GO_0005634 | Cellular component | nucleus |
| GO_0046982 | Molecular function | protein heterodimerization activity |
| GO_0003677 | Molecular function | DNA binding |
| GO_0000978 | Molecular function | RNA polymerase II cis-regulatory region sequence-specific DNA binding |
| GO_0001228 | Molecular function | DNA-binding transcription activator activity, RNA polymerase II-specific |
| GO_0003700 | Molecular function | DNA-binding transcription factor activity |
| GO_0005515 | Molecular function | protein binding |
| GO_0000981 | Molecular function | DNA-binding transcription factor activity, RNA polymerase II-specific |
| GO_0000976 | Molecular function | transcription cis-regulatory region binding |
| Gene name | NFYC |
| Protein name | Nuclear transcription factor Y subunit gamma (CAAT box DNA-binding protein subunit C) (Nuclear transcription factor Y subunit C) Nuclear transcription factor Y subunit gamma (CAAT box DNA-binding protein subunit C) (Nuclear transcription factor Y subunit C) (NF-YC) (Transactivator HSM-1/2) Nuclear transcription factor Y subunit gamma |
| Synonyms | |
| Description | FUNCTION: Component of the sequence-specific heterotrimeric transcription factor (NF-Y) which specifically recognizes a 5'-CCAAT-3' box motif found in the promoters of its target genes. NF-Y can function as both an activator and a repressor, depending on its interacting cofactors. FUNCTION: Component of the sequence-specific heterotrimeric transcription factor (NF-Y) which specifically recognizes a 5'-CCAAT-3' box motif found in the promoters of its target genes. NF-Y can function as both an activator and a repressor, depending on its interacting cofactors. . FUNCTION: Component of the sequence-specific heterotrimeric transcription factor (NF-Y) which specifically recognizes a 5'-CCAAT-3' box motif found in the promoters of its target genes. NF-Y can function as both an activator and a repressor, depending on its interacting cofactors. . FUNCTION: Component of the sequence-specific heterotrimeric transcription factor (NF-Y) which specifically recognizes a 5'-CCAAT-3' box motif found in the promoters of its target genes. NF-Y can function as both an activator and a repressor, depending on its interacting cofactors. . FUNCTION: Component of the sequence-specific heterotrimeric transcription factor (NF-Y) which specifically recognizes a 5'-CCAAT-3' box motif found in the promoters of its target genes. NF-Y can function as both an activator and a repressor, depending on its interacting cofactors. . FUNCTION: Component of the sequence-specific heterotrimeric transcription factor (NF-Y) which specifically recognizes a 5'-CCAAT-3' box motif found in the promoters of its target genes. NF-Y can function as both an activator and a repressor, depending on its interacting cofactors. . |
| Accessions | ENST00000453631.5 ENST00000372654.5 [Q13952-2] E9PL11 A0A0A0MT00 Q13952 ENST00000372669.8 ENST00000440226.7 [Q13952-2] Q5T6K5 E9PJA8 ENST00000456393.6 [Q13952-7] ENST00000425457.6 [Q13952-5] H0Y803 ENST00000372651.5 [Q13952-2] ENST00000372653.5 [Q13952-6] ENST00000416859.6 Q5T6K7 ENST00000525290.5 ENST00000372652.5 [Q13952-3] ENST00000414185.1 ENST00000308733.9 [Q13952-1] ENST00000427410.6 [Q13952-4] ENST00000534399.5 ENST00000531464.5 ENST00000530965.5 E9PQR2 ENST00000447388.8 [Q13952-2] E9PI99 |