Tissue | GTEx Coverage  | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| skin | 100% | 2298.30 | 1809 / 1809 | 100% | 90.54 | 472 / 472 |
| liver | 100% | 1732.63 | 225 / 226 | 100% | 76.31 | 406 / 406 |
| kidney | 100% | 4119.21 | 89 / 89 | 99% | 112.52 | 896 / 901 |
| thymus | 100% | 3703.06 | 653 / 653 | 99% | 102.73 | 601 / 605 |
| breast | 100% | 2578.39 | 459 / 459 | 99% | 78.66 | 1110 / 1118 |
| uterus | 100% | 2044.64 | 170 / 170 | 99% | 56.73 | 454 / 459 |
| pancreas | 100% | 2045.37 | 328 / 328 | 99% | 46.77 | 176 / 178 |
| adrenal gland | 100% | 5755.39 | 258 / 258 | 99% | 77.01 | 227 / 230 |
| bladder | 100% | 2414.62 | 21 / 21 | 99% | 72.68 | 497 / 504 |
| brain | 98% | 1537.95 | 2583 / 2642 | 100% | 39.47 | 703 / 705 |
| ovary | 100% | 2058.79 | 180 / 180 | 97% | 53.24 | 415 / 430 |
| lung | 100% | 3272.05 | 578 / 578 | 94% | 68.55 | 1091 / 1155 |
| prostate | 100% | 3178.76 | 245 / 245 | 93% | 73.22 | 469 / 502 |
| intestine | 100% | 2397.47 | 966 / 966 | 93% | 73.27 | 488 / 527 |
| esophagus | 100% | 1633.95 | 1444 / 1445 | 92% | 43.11 | 168 / 183 |
| stomach | 100% | 2350.61 | 359 / 359 | 80% | 59.07 | 229 / 286 |
| adipose | 100% | 2411.90 | 1204 / 1204 | 0% | 0 | 0 / 0 |
| eye | 0% | 0 | 0 / 0 | 100% | 86.42 | 80 / 80 |
| lymph node | 0% | 0 | 0 / 0 | 100% | 41.69 | 29 / 29 |
| spleen | 100% | 2721.84 | 241 / 241 | 0% | 0 | 0 / 0 |
| tonsil | 0% | 0 | 0 / 0 | 100% | 39.36 | 45 / 45 |
| ureter | 0% | 0 | 0 / 0 | 100% | 48.70 | 1 / 1 |
| blood vessel | 100% | 1829.40 | 1333 / 1335 | 0% | 0 | 0 / 0 |
| muscle | 99% | 1232.33 | 797 / 803 | 0% | 0 | 0 / 0 |
| peripheral blood | 99% | 2293.46 | 920 / 929 | 0% | 0 | 0 / 0 |
| heart | 98% | 1461.09 | 847 / 861 | 0% | 0 | 0 / 0 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| GO_0009313 | Biological process | oligosaccharide catabolic process |
| GO_0006689 | Biological process | ganglioside catabolic process |
| GO_0005576 | Cellular component | extracellular region |
| GO_0005886 | Cellular component | plasma membrane |
| GO_0035580 | Cellular component | specific granule lumen |
| GO_0016020 | Cellular component | membrane |
| GO_0005764 | Cellular component | lysosome |
| GO_0070062 | Cellular component | extracellular exosome |
| GO_0005737 | Cellular component | cytoplasm |
| GO_0043231 | Cellular component | intracellular membrane-bounded organelle |
| GO_0030054 | Cellular component | cell junction |
| GO_0043202 | Cellular component | lysosomal lumen |
| GO_0005765 | Cellular component | lysosomal membrane |
| GO_0016997 | Molecular function | alpha-sialidase activity |
| GO_0052795 | Molecular function | exo-alpha-(2->6)-sialidase activity |
| GO_0052796 | Molecular function | exo-alpha-(2->8)-sialidase activity |
| GO_0052794 | Molecular function | exo-alpha-(2->3)-sialidase activity |
| GO_0005515 | Molecular function | protein binding |
| GO_0004308 | Molecular function | exo-alpha-sialidase activity |
| Gene name | NEU1 |
| Protein name | Sialidase-1 Neurominidase Neuraminidase Sialidase-1 (EC 3.2.1.18) (Acetylneuraminyl hydrolase) (G9 sialidase) (Lysosomal sialidase) (N-acetyl-alpha-neuraminidase 1) Sialidase-1 (EC 3.2.1.18) (Lysosomal sialidase) (N-acetyl-alpha-neuraminidase 1) |
| Synonyms | NANH hCG_43692 |
| Description | FUNCTION: Catalyzes the removal of sialic acid (N-acetylneuraminic acid) moieties from glycoproteins and glycolipids. To be active, it is strictly dependent on its presence in the multienzyme complex. Appears to have a preference for alpha 2-3 and alpha 2-6 sialyl linkage. . FUNCTION: Catalyzes the removal of sialic acid (N-acetylneuraminic acid) moieties from glycoproteins and glycolipids. To be active, it is strictly dependent on its presence in the multienzyme complex. Appears to have a preference for alpha 2-3 and alpha 2-6 sialyl linkage. . FUNCTION: Catalyzes the removal of sialic acid (N-acetylneuraminic acid) moieties from glycoproteins and glycolipids. To be active, it is strictly dependent on its presence in the multienzyme complex. Appears to have a preference for alpha 2-3 and alpha 2-6 sialyl linkage. . FUNCTION: Catalyzes the removal of sialic acid (N-acetylneuraminic acid) moieties from glycoproteins and glycolipids. To be active, it is strictly dependent on its presence in the multienzyme complex. Appears to have a preference for alpha 2-3 and alpha 2-6 sialyl linkage. . |
| Accessions | ENST00000434496.2 Q6IBT5 ENST00000473226.5 ENST00000437432.2 ENST00000460245.5 ENST00000495464.5 ENST00000495201.5 ENST00000439648.2 Q6Q4G9 ENST00000465061.5 Q99519 ENST00000487340.5 ENST00000486127.5 ENST00000473972.5 ENST00000464056.5 ENST00000229725.4 ENST00000491768.5 ENST00000460116.5 ENST00000477637.2 Q6Q4G8 ENST00000475767.5 E9PIF4 Q6Q4G7 ENST00000375631.5 Q5JQI0 ENST00000465246.5 ENST00000473255.5 ENST00000423382.2 ENST00000411774.3 A0A0G2JKS5 ENST00000422978.2 |
