Name | Number of supported studies | Average coverage | |
---|---|---|---|
oligodendrocyte | 8 studies | 42% ± 12% | |
B cell | 7 studies | 18% ± 2% | |
smooth muscle cell | 6 studies | 26% ± 10% | |
CD4-positive, alpha-beta T cell | 5 studies | 19% ± 5% | |
naive thymus-derived CD4-positive, alpha-beta T cell | 5 studies | 19% ± 2% | |
endothelial cell | 5 studies | 19% ± 4% | |
regulatory T cell | 5 studies | 17% ± 1% | |
memory B cell | 5 studies | 16% ± 1% | |
natural killer cell | 4 studies | 18% ± 2% | |
naive thymus-derived CD8-positive, alpha-beta T cell | 4 studies | 20% ± 4% | |
CD16-negative, CD56-bright natural killer cell, human | 4 studies | 19% ± 1% | |
naive B cell | 4 studies | 19% ± 3% | |
epithelial cell | 3 studies | 20% ± 3% | |
CD16-positive, CD56-dim natural killer cell, human | 3 studies | 21% ± 2% | |
lymphocyte | 3 studies | 19% ± 3% | |
CD8-positive, alpha-beta T cell | 3 studies | 15% ± 0% | |
dendritic cell | 3 studies | 30% ± 2% | |
effector memory CD4-positive, alpha-beta T cell | 3 studies | 19% ± 5% | |
astrocyte | 3 studies | 23% ± 5% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
esophagus | 100% | 1720.67 | 1445 / 1445 | 100% | 19.89 | 183 / 183 |
skin | 100% | 2462.98 | 1808 / 1809 | 100% | 26.65 | 471 / 472 |
breast | 100% | 1007.05 | 459 / 459 | 99% | 16.52 | 1109 / 1118 |
intestine | 100% | 1616.09 | 964 / 966 | 99% | 13.96 | 522 / 527 |
lung | 100% | 1101.86 | 576 / 578 | 99% | 15.97 | 1143 / 1155 |
uterus | 100% | 1211.86 | 170 / 170 | 98% | 20.77 | 449 / 459 |
bladder | 100% | 1295.86 | 21 / 21 | 94% | 12.72 | 475 / 504 |
ovary | 100% | 677.79 | 180 / 180 | 94% | 8.34 | 403 / 430 |
stomach | 91% | 749.66 | 328 / 359 | 100% | 13.90 | 285 / 286 |
prostate | 100% | 1482.29 | 245 / 245 | 86% | 5.75 | 433 / 502 |
thymus | 99% | 696.91 | 647 / 653 | 82% | 6.28 | 495 / 605 |
kidney | 97% | 540.51 | 86 / 89 | 83% | 5.78 | 748 / 901 |
brain | 83% | 766.62 | 2192 / 2642 | 97% | 10.58 | 681 / 705 |
adrenal gland | 97% | 547.44 | 251 / 258 | 40% | 2.01 | 92 / 230 |
pancreas | 29% | 106.25 | 94 / 328 | 94% | 10.47 | 168 / 178 |
lymph node | 0% | 0 | 0 / 0 | 100% | 18.57 | 29 / 29 |
spleen | 100% | 1223.88 | 241 / 241 | 0% | 0 | 0 / 0 |
tonsil | 0% | 0 | 0 / 0 | 100% | 25.06 | 45 / 45 |
ureter | 0% | 0 | 0 / 0 | 100% | 4.47 | 1 / 1 |
blood vessel | 100% | 980.05 | 1333 / 1335 | 0% | 0 | 0 / 0 |
adipose | 100% | 901.41 | 1201 / 1204 | 0% | 0 | 0 / 0 |
peripheral blood | 100% | 3408.96 | 926 / 929 | 0% | 0 | 0 / 0 |
eye | 0% | 0 | 0 / 0 | 99% | 10.75 | 79 / 80 |
heart | 95% | 644.76 | 821 / 861 | 0% | 0 | 0 / 0 |
muscle | 85% | 412.72 | 685 / 803 | 0% | 0 | 0 / 0 |
liver | 23% | 90.05 | 53 / 226 | 37% | 2.18 | 151 / 406 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
GO_0007059 | Biological process | chromosome segregation |
GO_0051298 | Biological process | centrosome duplication |
GO_0051642 | Biological process | centrosome localization |
GO_0000132 | Biological process | establishment of mitotic spindle orientation |
GO_0051301 | Biological process | cell division |
GO_0001764 | Biological process | neuron migration |
GO_0007020 | Biological process | microtubule nucleation |
GO_0007100 | Biological process | mitotic centrosome separation |
GO_0051303 | Biological process | establishment of chromosome localization |
GO_0021987 | Biological process | cerebral cortex development |
GO_0016477 | Biological process | cell migration |
GO_0047496 | Biological process | vesicle transport along microtubule |
GO_0007405 | Biological process | neuroblast proliferation |
GO_0005874 | Cellular component | microtubule |
GO_0016020 | Cellular component | membrane |
GO_0031616 | Cellular component | spindle pole centrosome |
GO_0005813 | Cellular component | centrosome |
GO_0000776 | Cellular component | kinetochore |
GO_0005871 | Cellular component | kinesin complex |
GO_0005829 | Cellular component | cytosol |
GO_0045202 | Cellular component | synapse |
GO_0032154 | Cellular component | cleavage furrow |
GO_0042802 | Molecular function | identical protein binding |
GO_0008017 | Molecular function | microtubule binding |
GO_0005515 | Molecular function | protein binding |
Gene name | NDE1 |
Protein name | NudE neurodevelopment protein 1 (NudE nuclear distribution gene E homolog 1 (A. nidulans), isoform CRA_c) Nuclear distribution protein nudE homolog 1 NudE neurodevelopment protein 1 Alternative protein NDE1 Nuclear distribution protein nudE homolog 1 (NudE neurodevelopment protein 1) Epididymis secretory sperm binding protein (NudE neurodevelopment protein 1 isoform B) (NudE nuclear distribution gene E homolog 1 (A. nidulans), isoform CRA_b) NudE neurodevelopment protein 1 isoform A NudE neurodevelopment protein 1 isoform C Nuclear distribution protein nudE homolog 1 (NudE) |
Synonyms | NUDE hCG_38895 |
Description | FUNCTION: Required for centrosome duplication and formation and function of the mitotic spindle. Essential for the development of the cerebral cortex. May regulate the production of neurons by controlling the orientation of the mitotic spindle during division of cortical neuronal progenitors of the proliferative ventricular zone of the brain. Orientation of the division plane perpendicular to the layers of the cortex gives rise to two proliferative neuronal progenitors whereas parallel orientation of the division plane yields one proliferative neuronal progenitor and a post-mitotic neuron. A premature shift towards a neuronal fate within the progenitor population may result in an overall reduction in the final number of neurons and an increase in the number of neurons in the deeper layers of the cortex. . |
Accessions | ENST00000674538.1 ENST00000396354.6 [Q9NXR1-2] ENST00000396355.5 [Q9NXR1-2] ENST00000674581.1 I3L522 A0A0J9YYF5 X5DP35 ENST00000674995.1 ENST00000632288.1 ENST00000631844.1 [Q9NXR1-2] ENST00000577101.6 ENST00000632578.1 ENST00000674900.1 ENST00000570727.5 A0A6Q8PHH1 I3L2S8 ENST00000633132.1 ENST00000574109.5 I3L2T8 ENST00000576502.5 ENST00000674888.1 [Q9NXR1-2] A0A6Q8PEY3 ENST00000572756.6 A0A6Q8PG46 L8E8T4 I3L2R3 A0A0J9YY14 ENST00000572967.1 ENST00000573203.5 X5DRF9 Q9NXR1 I3L533 ENST00000634195.1 X5DR54 ENST00000674588.1 A0A6Q8PGV6 I3L464 ENST00000632452.1 ENST00000631789.1 ENST00000632668.1 ENST00000674554.1 [Q9NXR1-2] ENST00000675171.1 I3L2R9 ENST00000631507.1 ENST00000573694.5 ENST00000675951.1 [Q9NXR1-2] ENST00000631923.1 [Q9NXR1-2] I3L3G9 ENST00000675926.1 [Q9NXR1-2] |