NCF4 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_0045730Biological processrespiratory burst
GO_0042554Biological processsuperoxide anion generation
GO_0006909Biological processphagocytosis
GO_0032010Cellular componentphagolysosome
GO_0010008Cellular componentendosome membrane
GO_0005829Cellular componentcytosol
GO_0043020Cellular componentNADPH oxidase complex
GO_0005886Cellular componentplasma membrane
GO_0016020Cellular componentmembrane
GO_0005737Cellular componentcytoplasm
GO_0016176Molecular functionsuperoxide-generating NADPH oxidase activator activity
GO_0032266Molecular functionphosphatidylinositol-3-phosphate binding
GO_0005515Molecular functionprotein binding

IV. Literature review

[source]
Gene nameNCF4
Protein nameNeutrophil cytosol factor 4 (NCF-4) (Neutrophil NADPH oxidase factor 4) (SH3 and PX domain-containing protein 4) (p40-phox) (p40phox)
Neutrophil cytosol factor 4 (Neutrophil cytosolic factor 4, 40kDa, isoform CRA_a)
Neutrophil cytosol factor 4 (Neutrophil cytosolic factor 4)
NCF4 protein
Neutrophil cytosol factor 4
Neutrophil cytosolic factor 4
SynonymsSH3PXD4
hCG_40038
DescriptionFUNCTION: Component of the NADPH-oxidase, a multicomponent enzyme system responsible for the oxidative burst in which electrons are transported from NADPH to molecular oxygen, generating reactive oxidant intermediates. It may be important for the assembly and/or activation of the NADPH-oxidase complex. .

AccessionsQ15080
A0A0G2JR51
ENST00000625504.2
B0QY04
ENST00000628938.2
ENST00000614157.1
ENST00000447071.5
ENST00000650827.1
Q6FGM9
A0A217FLJ2
ENST00000626011.2
A0A494BZS1
ENST00000650698.1
ENST00000397147.7 [Q15080-3]
ENST00000248899.11 [Q15080-1]