Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
prostate | 100% | 7759.93 | 245 / 245 | 100% | 81.91 | 502 / 502 |
thymus | 100% | 8177.76 | 653 / 653 | 100% | 71.29 | 605 / 605 |
ovary | 100% | 4984.64 | 180 / 180 | 100% | 50.74 | 429 / 430 |
brain | 100% | 8460.33 | 2635 / 2642 | 100% | 69.72 | 705 / 705 |
adrenal gland | 100% | 8789.79 | 258 / 258 | 100% | 84.34 | 229 / 230 |
kidney | 100% | 7393.61 | 89 / 89 | 100% | 49.68 | 897 / 901 |
breast | 100% | 7929.23 | 459 / 459 | 99% | 45.89 | 1106 / 1118 |
skin | 100% | 5647.26 | 1804 / 1809 | 99% | 48.02 | 467 / 472 |
intestine | 100% | 6622.20 | 966 / 966 | 98% | 31.41 | 519 / 527 |
lung | 100% | 8905.52 | 578 / 578 | 98% | 32.33 | 1135 / 1155 |
pancreas | 98% | 3148.13 | 322 / 328 | 100% | 37.71 | 178 / 178 |
stomach | 100% | 5372.71 | 358 / 359 | 98% | 30.82 | 280 / 286 |
uterus | 100% | 7792.32 | 170 / 170 | 98% | 32.26 | 448 / 459 |
bladder | 100% | 5425.19 | 21 / 21 | 97% | 32.19 | 487 / 504 |
esophagus | 100% | 5474.38 | 1441 / 1445 | 97% | 25.97 | 177 / 183 |
liver | 95% | 2437.61 | 215 / 226 | 97% | 25.93 | 393 / 406 |
adipose | 100% | 8270.18 | 1204 / 1204 | 0% | 0 | 0 / 0 |
eye | 0% | 0 | 0 / 0 | 100% | 78.67 | 80 / 80 |
lymph node | 0% | 0 | 0 / 0 | 100% | 43.61 | 29 / 29 |
spleen | 100% | 12504.62 | 241 / 241 | 0% | 0 | 0 / 0 |
tonsil | 0% | 0 | 0 / 0 | 100% | 30.38 | 45 / 45 |
ureter | 0% | 0 | 0 / 0 | 100% | 23.00 | 1 / 1 |
blood vessel | 100% | 8699.53 | 1334 / 1335 | 0% | 0 | 0 / 0 |
heart | 98% | 3766.39 | 845 / 861 | 0% | 0 | 0 / 0 |
muscle | 98% | 3005.29 | 784 / 803 | 0% | 0 | 0 / 0 |
peripheral blood | 96% | 3041.73 | 888 / 929 | 0% | 0 | 0 / 0 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
GO_0000122 | Biological process | negative regulation of transcription by RNA polymerase II |
GO_0006357 | Biological process | regulation of transcription by RNA polymerase II |
GO_0005654 | Cellular component | nucleoplasm |
GO_0000785 | Cellular component | chromatin |
GO_0000978 | Molecular function | RNA polymerase II cis-regulatory region sequence-specific DNA binding |
GO_0046983 | Molecular function | protein dimerization activity |
GO_0005515 | Molecular function | protein binding |
GO_0000981 | Molecular function | DNA-binding transcription factor activity, RNA polymerase II-specific |
Gene name | MXD4 |
Protein name | Max dimerization protein 4 (Max dimerizer 4) (Class C basic helix-loop-helix protein 12) (bHLHc12) (Max-associated protein 4) (Max-interacting transcriptional repressor MAD4) MAX dimerization protein 4 |
Synonyms | MAD4 BHLHC12 |
Description | FUNCTION: Transcriptional repressor. Binds with MAX to form a sequence-specific DNA-binding protein complex which recognizes the core sequence 5'-CAC[GA]TG-3'. Antagonizes MYC transcriptional activity by competing for MAX and suppresses MYC dependent cell transformation (By similarity). . |
Accessions | ENST00000337190.7 ENST00000513380.1 Q14582 H0Y8Z5 |